Conserved Protein Domain Family
Dfp1_Him1_M

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pfam08630: Dfp1_Him1_M 
Dfp1/Him1, central region
This is the middle regions described by Ogino et al. This region, together with the C-terminal zinc finger (pfam07535) is essential for the mitotic and kinase activation functions of Dfp1/Him1.
Statistics
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PSSM-Id: 400796
View PSSM: pfam08630
Aligned: 97 rows
Threshold Bit Score: 117.288
Threshold Setting Gi: 328861543
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003645198 200 DVLYRAHKNgYMKIWNYDKAMRFLKNLDVDLDAIEKQQQYGICQTSHgsilmmganqshnsvsvggvitattNATATLSN 279 Eremothecium cy...
CAR65532     187 DIFHDACSL-KIKVWDYEKVFRFLKNLGVNESSYKYDDNTKFNK------------------------------NGDLYN 235 Debaryomyces ha...
CCE73435     182 DIFNDVHNL-KIKVWNYDKVFRFLKNLGVCEPSGKIEKGNK---------------------------------TGDLYN 227 Millerozyma far...
EGW29953     129 DIFSNVASL-KIKVWNYEKVFRFLKNLGVNILTGVDENALNTHTILPpsltt---------------dstskTNRDNLYN 192 Spathaspora pas...
CCE45335     409 DIFSNVPKF-KTKVWSYEKLFRFMKNLGLNNISDDQLSTGASVNANT-------------------------TANNNLYN 462 Candida parapsi...
EDK46964     471 DIFCNVSRL-KVKVWNYDKLFRFMKNLGLGSLTDEQVNAGNAAQRD--------------------------TPTNNLYN 523 Lodderomyces el...
ABN67914     151 DIFSNVSQL-KIKVWDYEKVFRFLKNLGINIVTGIDESV-----------------------------------HHNLYN 194 Scheffersomyces...
EMG47657     182 DIFSNVAKG-TIKVWNYEKVFRFLKNLGINIQTGADELGVNTHTVLPpsltn---------------nnnhdTSKNNLYT 245 Candida maltosa...
Q5A5B4       162 DIFSNVSKA-SIKVWNYDKVFRFLKHLGINIQTGVDELAVNTHTILPpsl-------------------tnnNEKPDLYN 221 Candida albicans
EER31264     157 DIFSNVSKG-GIKVWNYDKVFRFLKNLGINIQTGVDELAVNTHTVLPpsltng--------------tsttnNDKNNLYT 221 Candida tropica...
XP_003645198 280 LLENERLYGPNDRDPRTKRDDVHYFKYPHVYLYDLWQTWAPLITMEWkpseindPeKLPYPNIKPGTFGRCPFVG 354 Eremothecium cymbala...
CAR65532     236 LLKEEKIFGANDRDPNARRDDLHYLERNYLYAYDLAQNFRPIAVREWn--------DTPYPKISNTLDGKCPFIP 302 Debaryomyces hanseni...
CCE73435     228 LLKEEKIFGSTDRDPNAKRDDLHYLEKNYLYVYDLSQNVRPIAVREWa--------DDSYPKLHLTLDGKCPFVS 294 Millerozyma farinosa...
EGW29953     193 LLKEEKIYGSTDRDPNAKRDDLHYLGKNYLFVYDLLQKVRPIAVREW-------HdDHSYTTLNLTMDGKCPFIf 260 Spathaspora passalid...
CCE45335     463 LLKEEKLYGVADRDPNARRDDFHYFSKNYLYVYDLSQTVRPIAIREW-------GnD--YPVLHLTLDGKCPFIE 528 Candida parapsilosis
EDK46964     524 LLKEEKIYGSADRDPNARRDDFHYFGKNYLYVYDLSQAVRPIAVKEW-------GnE--YPTLNLTLDGKCPFIY 589 Lodderomyces elongis...
ABN67914     195 LLKEEKIFGLTDRDPNAKRDDLHYFDKNYLYVYDLSQKVRPIAIREWn--------DSSYPVLNLTLDGKCPFIS 261 Scheffersomyces stip...
EMG47657     246 LLKEEKIYGSADRDPNAKRDDFHYLGKNYLYVYDLTQIVRPIAVREW-------AdD--YPVMSLTLDGKCPFID 311 Candida maltosa Xu316
Q5A5B4       222 LLKEEKIYGSTDRDPNAKRDDLHYLGKNYLYVYDLTQTVRPIAIREW-------SdH--YPVMQLSLDGKCPFIE 287 Candida albicans
EER31264     222 LLKEEKIYGSTDRDPNAKRDDLHYFSKFYLYVYDLTQMVRPIAVREW-------GsN--YPTMRLTLDGKCPFIi 287 Candida tropicalis M...
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