Conserved Protein Domain Family
RPAP1_C

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pfam08620: RPAP1_C 
RPAP1-like, C-terminal
Inhibition of RPAP1 synthesis in Saccharomyces cerevisiae results in changes in global gene expression that are similar to those caused by the loss of the RNAPII subunit Rpb11. This entry represents the C-terminal region that contains the motif GLHHH. This region is conserved from yeast to humans.
Statistics
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PSSM-Id: 400786
View PSSM: pfam08620
Aligned: 102 rows
Threshold Bit Score: 64.8621
Threshold Setting Gi: 145348090
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EDK45600      356 DMRFDFKGNLVQInidkedvtdSlnggsregKGEIPTY---------LG-----LHHHSENPHMAGYTLSELAHLSRSTQ 421  Lodderomyces ...
XP_004231458  379 ELRFSLDGNIVK----------S--------EFDVSKSgntssyaeqNLserdyLRTEG-DPGAAGYTIKEAVALARSLV 439  tomato
XP_002438609  355 SCRFTLDGDILG-------------------FQFSHEQqdgkkmhseSVaerdfLRTEG-DPAAVGYTIKEAVALTRSMV 414  sorghum
XP_002968364  220 SMRFSLDGEVIS----------------------SSNTdmqddsdlsSVaqrdyLRAEG-DPSALGYTIKEAALLSRSTV 276  Selaginella m...
XP_002503780  529 SVRFTLEGVPLN--------------------ADEQPAagrqasrlgSAverdpLRSGTQNPADLGYTTRECLELARSSV 588  Micromonas co...
XP_003057932  311 STRYALDGTALS--------------------AEAHADasalanaagSAvtrdpLRA---DGADAGYTLSEALDLSRSSV 367  Micromonas pu...
XP_001418489  296 HVRFALDGSPLL---------------------DATVDvatgsapapLPterdpLRAG--EGSDIGYTFQEACALTRSSV 352  Ostreococcus ...
EGG22506      402 NWRFGFRGELIVN------------------SEDIPTH---------LG-----LHHHGQDAAEAGYTIQELSLLIRSTN 449  Cavenderia fa...
EFA78094      400 EWRFDFNGVVIQS------------------GQDIPVH---------QG-----LHHHGDEAAEAGYTINELIQLAKSTN 447  Heterostelium...
Q54VP8        380 EWRFNFTGEIIQR------------------GSSTPTS---------QG-----LHHHGSEAGEAGYTLNEIIMLIKSSN 427  Dictyostelium...
EDK45600      422 PGQRCISIQTLGRLLHK 438  Lodderomyces elongisporus NRRL YB-4239
XP_004231458  440 PGQRTFAFHLIASVLDR 456  tomato
XP_002438609  415 PGQRVLALQLLASILNR 431  sorghum
XP_002968364  277 PAHRAAGVQLLGTIFSN 293  Selaginella moellendorffii
XP_002503780  589 PAQRSVGLNVLTRVLAH 605  Micromonas commoda
XP_003057932  368 PAQRVAGLTLLARVLAR 384  Micromonas pusilla CCMP1545
XP_001418489  353 ASQRTIGLQIIGKILKL 369  Ostreococcus lucimarinus CCE9901
EGG22506      450 HSQKTTALRILSDIFAN 466  Cavenderia fasciculata
EFA78094      448 IGQSSVTLRTISFILQK 464  Heterostelium album PN500
Q54VP8        428 HSQKCIALKTLTFILQK 444  Dictyostelium discoideum AX4
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