6AHR


Conserved Protein Domain Family
Ribonuc_P_40

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pfam08584: Ribonuc_P_40 
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Ribonuclease P 40kDa (Rpp40) subunit
The tRNA processing enzyme ribonuclease P (RNase P) consists of an RNA molecule and at least eight protein subunits. Subunits hpop1, Rpp21, Rpp29, Rpp30, Rpp38, and Rpp40 (this entry) are involved in extensive, but weak, protein-protein interactions in the holoenzyme complex.
Statistics
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PSSM-Id: 400757
View PSSM: pfam08584
Aligned: 51 rows
Threshold Bit Score: 189.439
Threshold Setting Gi: 514655564
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6AHR_L               75 HELITPEFISTFIKK-GSCYALTYNTHIDEDNTVALLPnGKLILSLDKDTYEET--GLQGH-------PSQFSGr--kIM 142 human
Q6C7H2               65 predgSSFSASVFQK-SDAWIIS-KSRIDSDNVFAVWR-GNVHMSLTRSTYQTS--GLNGK-------KSRYGD------ 126 Yarrowia...
WGS:AATM:SJAG_00955  70 sCLLSSSLYESFVQN-GTITLLS-DSLPDSSSSIALYN-GTIWISMDKDTYLCA--GLSAK-------ASGNQPk---NT 134 Schizosa...
XP_001603266         80 vELINKEFIESFVKK-GELNLLAIEKRIDVDNSAAILPtGHLLLILDRESYQRL--GLEGK-------PSYFERe--nPS 147 jewel wasp
EGI64413             75 SDLLNIEFIEAFVKK-GEINLLTLENKIDLENSICVTPtGYLILSLLTDDYQAL--GLEGK-------PSVFSHk--sHT 142 Panamani...
XP_019884111         74 cDLLSTEFIEAFVKK-GEVSLMTIENKIDLQNSICVTPtGYLLLSLLTEDYQAL--GLEGK-------ASSFNCk--pHT 141 Florida ...
2_pfamImport          1 -MFLSPAFIKEYLQDgGSVFMVAKNVAVDAAQSAMLLPsGQLLLLVDADTYQQL--GIVGEkygralpATSRTr---rGQ 74 
EEY62536             97 DMFLSPTFIRDYLMDgGAVFMVAKNTAVDASQSAMLLPsGQLLLLVDADTYQQL--GIVGEkygkavpATSRSAhvkqAQ 174 Phytopht...
5_pfamImport          1 TMFLLPAFIRTYLMDgGAVFMVAKNVAVDASQSAMLLPsGHLLLLVDADTYHQL--GIVGGkygkaapASSRTAhekqGQ 78 
XP_311176            80 IELLKNEFVEAFVKR-GTLYAVSTNINLESGGCLVITPqGELEMSLSRETYQMVkgNLDGSvi-------------skRG 145 Anophele...
6AHR_L              143 KF-IVSIDLMELSLNLDSKK----YERISWSFKEKKpLKFDFLLAWHK---TGS---EES-T--MMSYfskyqiq----- 203 human
Q6C7H2              127 KY-LISFNLRNPNFHIGTKQ----HNRFLFGLEQLDkLHPDLEYSVTVhanDARyvsEYLsNvkEVPLk----------- 190 Yarrowia...
WGS:AATM:SJAG_00955 135 RW-DALFNISDTPFKYGSKN----FERLRKGLERL--PDFNFI--------------ATCpSdkIQDFleaapftv---- 189 Schizosa...
XP_001603266        148 RY-VVTIDLKEEKLTPGKKY----YERIHNSLDKLLdLTFNVIVAWEPpe------eKLCpSsvAAWFqkrgyav----- 211 jewel wasp
EGI64413            143 RY-IVRIDLTNENFIPGKKN----YERIRIALEERLtQKFDVIVSWDPpd------iSMCpSsiAAWFyarnynv----- 206 Panamani...
XP_019884111        142 RY-VVTINLKSENFVPGKKN----YERTRIALEQRLkQSFDVIVSWDPpn------tNLCpSsiAAWFyarnyev----- 205 Florida ...
2_pfamImport         75 KY-VITLDLTSSAFAEEGENa--fRDRVRECLSSRLeDLEMLLCAYNArgsARTilfGDDdTvpRKRVel---------- 141
EEY62536            175 KY-VITLDLTSSTFAGEEVNt--fRDRVRKCLSTKLeDLEMLLCAYNQrgsARTilfGDDdQipRSRVel---------- 241 Phytopht...
5_pfamImport         79 KY-VITLDLTSLMFLAEEGNhhhlGERVRRLLSTKLdHLEMLLCAYNQrgsPRTilfGEDdTvpRVRVel---------- 147
XP_311176           146 DMvVIKLDLKSPKCREQLGHvnlaFD-----------ITLRWIPPKSTttkENN---VPDpQvhGSSIaeylrvvcrlqv 211 Anophele...
6AHR_L              204 --------ehqpkvALSTLRDLQCPVLqsselegt-----------------pevscraLELFDWLGAVFSNVDLNNe-- 256 human
Q6C7H2              191 --------------TTVSERNVLVPSMtppvvpeltdahsgakvdvsqkyrdhlfeswaLGLQEWVGLASIGAGRIAsd- 255 Yarrowia...
WGS:AATM:SJAG_00955 190 -------rcepirlEHNTLRSQKIPPvlfepnfpyknn---------ddddlstlkenaFDILEYMSLLGLHSPLLQst- 252 Schizosa...
XP_001603266        212 -------sachqqmMQRVEYTLDIPLLedn--------------------------fdrDEFFEWLGIFSIGGNLVNed- 257 jewel wasp
EGI64413            207 -------clccqkfSQKIKYSLTIPTYedtc------------------------nntdIDFFEWLGVFSIDGDLSTk-- 253 Panamani...
XP_019884111        206 -------clchqtfSQRTKYSMALPTLqeg--------------------------cnlDKFFEWLGIFSIGGDLSNg-- 250 Florida ...
2_pfamImport        142 ------------dgQTTTFNEVFLPKFdafyavlkkkger-------edgdndklrtslQEAYDWLGLVAC--RLTDlle 200
EEY62536            242 ------------naKMTTFSDVFLPKFdafykeiaavekr-------gaedgntlrtslQEAYDWLGVVAC--GLTDllq 300 Phytopht...
5_pfamImport        148 ------------ngKTTTFNDVFLPKFdafykalsasdeh-------gdgrmdtlrtslHEAYDWLGLVAC--RLTNllq 206
XP_311176           212 envpdgykkitrtkecipliDTSNPFkdgeq-----------------------ayirqDQLLEYIGVLALdcn------ 262 Anophele...
6AHR_L              257 ---PNNFISTY---C-CPEPStv---vaKAYLCTITGFILPEKICLLLEHLCHYFDEPKLA-PWVTLSVQGFADSPVSWE 325 human
Q6C7H2              256 -dnVNNLFSQYqveDgQPA---------NVTNIQVVGM------CPLLASKLKILGEQTNA-PFFAFTVYGVQDTPYSWD 318 Yarrowia...
WGS:AATM:SJAG_00955 253 -naTDPYVSTY---T-IPMKNagepqtgDITQITVSGLLTPDICLCLYSRIQSP--------EWFFTGLVGYPCTPVSWI 319 Schizosa...
XP_001603266        258 --rEAEYVSSY---K-NSNPKme---vgQVQYLQFTGFLTRQKIEKIFNMLREYATANNETlPWCSLDVQGFADSPVSWG 328 jewel wasp
EGI64413            254 --rEDNYANTY---Q-CPSPSih---vkQVQYLQWTGFFTRQKIQEVYNVLKQYILSRDSL-PWISLDIQGFADSAISFD 323 Panamani...
XP_019884111        251 --eTDNYVNTY---E-CPPLSid---igQVQHLQWTGFFTRQKMHEMYNALKEYVLSRKTL-PWVSLDVQGFADSPTSWD 320 Florida ...
2_pfamImport        201 rqkLEEYVSTF---SgIPDSFece-pdsEITTVRWRGLVAAPFCSTVVEKVQRAVKNREV--PWGAVTVWGFPDVFVSWV 274
EEY62536            301 rqkLEEYVSTF---TgIPDSFesv-pgdEITTVRWRGLLAAPFCSTIVEKVQRSVKNAEL--PWAAVTVWGFPDVFpq-- 372 Phytopht...
5_pfamImport        207 rekLEEYVSTF---AgIPDSFece-pdgEITTVQWRGLLAAPFCSAIAEKVQLAVKNGDL--PWGAVTVWGFPDVFVSWV 280
XP_311176           263 -saPIEYVSSY---R-LDECKkk---tdTVTILHRQGVITPEEADGSIMRLVELVGECDTI-PWVGMHFQGFSHTPVDLI 333 Anophele...
6AHR_L              326 K----------------NEHGFRKGGEHL-YNFVI 343 human
Q6C7H2              319 N----------------KEHQYDNGGEND-YTIID 336 Yarrowia lipolytica
WGS:AATM:SJAG_00955 320 G----------------KVHVHNYSGENAiYTLsr 338 Schizosaccharomyces japonicus yFS275
XP_001603266        329 L----------------KEHNFYTDGDNS-YTIVL 346 jewel wasp
EGI64413            324 L----------------KEHTFLTDGDNS-YTIVF 341 Panamanian leafcutter ant
XP_019884111        321 L----------------KEHMFFTDGDNS-YTIIf 338 Florida carpenter ant
2_pfamImport        275 QpvktgkgstrksesqrREHGYLGNGSNN-YTLLM 308
EEY62536            373 ----------------rREHGYLGNGSNN-YTLLI 390 Phytophthora infestans T30-4
5_pfamImport        281 QqtklnkstkgtngsqrREHGYLGNGSNN-YTILM 314
XP_311176           334 Yr---------------GDQGVSLNQDSA-YTMVI 352 Anopheles gambiae str. PEST
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