5HOU


Conserved Protein Domain Family
P53_TAD

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pfam08563: P53_TAD (This model is not part of the current CDD release)
P53 transactivation motif
The binding of the p53 transactivation domain by regulatory proteins regulates p53 transcription activation. This motif is comprised of a single amphipathic alpha helix and contains a highly conserved sequence.
Statistics
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PSSM-Id: 518344
Aligned: 19 rows
Threshold Bit Score: 30.2264
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5HOU_A         9 SDPSVEPPLSQETFSDLWKLLPENN 33  synthetic construct
XP_006112199   5 LDTGLDLPLSQESFSDLWKTLSPLA 29 
1_pfamImport   1 LALGQDLPDSQDSFAELWGNVVSPP 25 
XP_025761189   9 LQLSQNLPLSQDSFKELWDKIIPST 33 
2_pfamImport   1 METNFPLPLSQDTFHELWNTVVLST 25 
Q92143         2 EEADLTLPLSQDTFHDLWNNVFLST 26  southern platyfish
KPP69315     112 EEDMPSLPFSQESFQELWKDLMPAP 136
XP_009057946  10 GNTNSQPPMSQDTFDFLWKTLGDAT 34 
EMP41147       2 LDPGLEPPLSQESFSDWWSMMLQPT 26 
XP_005999863  56 SESGLE-PLSQESFADLWNLLPTSM 79  coelacanth
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