1K7G,1KAP


Conserved Protein Domain Family
Peptidase_M10_C
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pfam08548: Peptidase_M10_C (This model is not part of the current CDD release)
Peptidase M10 serralysin C terminal
Serralysins are peptidases related to mammalian matrix metallopeptidases (MMPs). The peptidase unit is found at the N terminal while this domain at the C terminal forms a corkscrew and is thought to be important for secretion of the protein through the bacterial cell wall. This domain contains the calcium ion binding domain pfam00353.
Links
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Statistics
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PSSM-Id: 518334
Aligned: 13 rows
Threshold Bit Score: 324.333
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1K7G_A       260 ANMTTRTGDSVYGFNSNTDRDFYTATDSSKALIFSVWDAGGTDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVT 339 Dickeya chrysan...
Q6D3F9       258 ANMDTRTGDTVYGFNSNTGRDFYTTNSNSQKLIFSVWDAGGNDTFDFSGYKDNQIIDLNEGRFSDVGGLKGNVSIAHGVT 337 Pectobacterium ...
WP_046493259 218 ANLETRTGNTIYGFNSNSGRPYLSAENADDPLIFCVWDAGGIDTFDFSGYRQNQRINLKSSQFSDVGGLKNNVSIAYRVI 297 Candidatus Hami...
1_pfamImport   1 ANLHTRTGDTVYGFNSTSYRDHFTATHASDALIFCVWDAGGNDTFDFSGYKQNQMINLNELCFSDVGGLKGNVSIAADVT 80 
2_pfamImport   1 ANMETRKGDTVYGFNSNTDRDFMTATDANSKLIFSVWDAGGEDTFDFSGFTQNQRINLNAGSFSDVGGLKGNVSIARGVV 80 
Q7N8R3       255 ANNTIRADDTVYGFNSNTDRDFYTAKDENSKLLFTAWDTGGNDTFDFSGFTQDQRINLNEASFSDVGGLKGNVSIARGVT 334 Photorhabdus la...
Q03023       257 ANLTTRTGDTVYGFNSNTERDFYSATSSSSKLVFSVWDAGGNDTLDFSGFSQNQKINLNEKALSDVGGLKGNVSIAAGVT 336 Pseudomonas aer...
Q87ZU2       257 ANLSTRATDTVYGFNSTAGRDFYSATSASSKVVFSVWDGGGKDTLDFSGFTQNQKINLNAASFSDVGGMVGNVSIAKGVV 336 Pseudomonas syr...
WP_013317956 258 ANMSTRTGDTVYGFHSNSGRDFYTATDSKTPLIFSVWDAGGNDTFDFSGYSANQRISLISGTFSDVGGLKGNVSIAAGAV 337 Dickeya dadantii
WP_013317949 258 ANMTTRTGDTVYGFNSNTDRDFYTATSSSKALIFSVWDAGGNDTFDFSGYSNNQRINLNEGSLSDVGGLKGNVSIAHGVT 337 Dickeya dadantii
WP_013317950 260 ANMTTRTGDSVYGFNSNTDRDFYTATDSSKALIFSVWDAGGNDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVT 339 Dickeya dadantii
WP_004236000 260 ANYNIRTDDTVYGFDSNTGRDYYSAQNATDKLIFTVWDGGGNDTLNFSRYKQDQKISLREGDFSDVGGLTGNVSIAHGVV 339 Morganella
1KAP_P       257 ANLTTRTGDTVYGFNSNTERDFYSATSSSSKLVFSVWDAGGNDTLDFSGFSQNQKINLNEKALSDVGGLKGNVSIAAGVT 336 Pseudomonas aer...

1K7G_A       340 IENAIGGSGNDILVGNSADNILQggagn---------------------------------------------------- 367 Dickeya chrysan...
Q6D3F9       338 IENAIGGSGNDIIIGNSADNILQ--------------------------------------------------------- 360 Pectobacterium ...
WP_046493259 298 IENAISGSGDDEIIGNEVDNVLRggkgadliygeqgcdrlfgdegndrlyggegadklvggrgsdqlwggkdndyllgge 377 Candidatus Hami...
1_pfamImport  81 IENAIGGSGHDDIIGNHTNNILT--------------------------------------------------------- 103
2_pfamImport  81 IENAIGGSGDDILVGNSADNILKggagd---------------------------------------------------- 108
Q7N8R3       335 IENAIGGSGNDVLIGNDAANTLKggagd---------------------------------------------------- 362 Photorhabdus la...
Q03023       337 VENAIGGSGSDLLIGNDVANVLKggagn---------------------------------------------------- 364 Pseudomonas aer...
Q87ZU2       337 VENAIGGSGNDLLIGNAAANDLKggagn---------------------------------------------------- 364 Pseudomonas syr...
WP_013317956 338 MENAIGGSGHDVIVGNLSDNRIDggagn---------------------------------------------------- 365 Dickeya dadantii
WP_013317949 338 IENAIGGSGNDLLIGNNADNILRggagd---------------------------------------------------- 365 Dickeya dadantii
WP_013317950 340 IENAIGGSGNDILVGNSADNILQggagn---------------------------------------------------- 367 Dickeya dadantii
WP_004236000 340 IENAFGGRGNDVIIGNDADNILMgnggn---------------------------------------------------- 367 Morganella
1KAP_P       337 VENAIGGSGSDLLIGNDVANVLKggagn---------------------------------------------------- 364 Pseudomonas aer...

1K7G_A       368 -----------dvlyGGAGADTLYG---------------------------GAGRDTFVYGSGQDST-VAAYDWIADFQ 408 Dickeya chrysan...
Q6D3F9       361 ---------------GGAGADTLTG---------------------------GAGKDIFVYASASDSSnTTGYDTITDFQ 398 Pectobacterium ...
WP_046493259 378 dqdflfggqgndrlvGGRGRDQLWGekgddtllgemgddwlsggtgadkltgGPGRDIFVYQTCDDSS-TLSTDTICDFE 456 Candidatus Hami...
1_pfamImport 104 ---------------GNGGSDQLWG---------------------------NGGNNTFRYASARDSM-TTSPDTIHDFK 140
2_pfamImport 109 -----------diiyGGLGGDHLWG---------------------------GEGNDIFVYLSGKESL-KNNPDWIHDFV 149
Q7N8R3       363 -----------diiyGGLGADNLWG---------------------------GEGNDTFVYLSAKESP-PLERDWIHDFV 403 Photorhabdus la...
Q03023       365 -----------dilyGGLGADQLWG---------------------------GAGADTFVYGDIAESS-AAAPDTLRDFV 405 Pseudomonas aer...
Q87ZU2       365 -----------diiyGGGGADSLTG---------------------------GAGADIFVFGASSDSN-RAAQDTIRDFV 405 Pseudomonas syr...
WP_013317956 366 -----------dvlyGDGGADILTG---------------------------GAGKDIFVYAWEKDSL-SSAPDTITDFQ 406 Dickeya dadantii
WP_013317949 366 -----------dilyGGGGADRLYG---------------------------GSGRDTFVYTAVSDSK-VAAPDWILDFQ 406 Dickeya dadantii
WP_013317950 368 -----------dvlyGGAGADTLYG---------------------------GAGRDTFVYGSGQDST-VAAYDWIADFQ 408 Dickeya dadantii
WP_004236000 368 -----------dvlyGGAGQDQLWG---------------------------GTGNDIFVFSAVTDSL-YDHPDHIRDFS 408 Morganella
1KAP_P       365 -----------dilyGGLGADQLWG---------------------------GAGADTFVYGDIAESS-AAAPDTLRDFV 405 Pseudomonas aer...

1K7G_A       409 KGIDKIDLSAFR----Ne---GQLSFVqDQFTGKGQ-EVMLQWDAANSITNLWLHEAGH------SSVDFLVRIVG-QAA 473 Dickeya chrysan...
Q6D3F9       399 RGIDKIDLSALNq---N----KDLQFV-DSFTGLGN-EALLDWDAGSNTTNLWLNFAGQ------TTPDFLVHIVG-QPS 462 Pectobacterium ...
WP_046493259 457 VGIDKIDLSRITn---Ni---KNIQFV-DRFHFKGQtEIQQRHNSILNITYLMIDFSDSieknslNNNDMMIKFTGnKKL 529 Candidatus Hami...
1_pfamImport 141 SGRDKIDLSQLMp---St---DRVIFV-DRLSFNGQtEMGQQYNEVADITYLMIDFDAQv-----SECDMMIKFTGrHHF 208
2_pfamImport 150 SGEDKIDLSDFNf---Gg--dGDIKFV-DSFSGKAG-EVLFTYDEENDVTDLEISLGGDl-----AGNDFLVKVIG-QPL 216
Q7N8R3       404 SGKDKIDVSLFDl---GeagkGGVKFV-REFTGEVG-EAVLRYNTVDKVNDFAINLGGEf-----SYDDFWVKIVG-EPI 472 Photorhabdus la...
Q03023       406 SGQDKIDLSGLDa---FvnggLVLQYV-DAFAGKAG-QAILSYDAASKAGSLAIDFSGD------AHADFAINLIG-QAT 473 Pseudomonas aer...
Q87ZU2       406 SGQDKIDVSAISt---L----SALQFV-NAFSGHAG-EAILNYNQSSNLGSLAIDFTGQ------GAGDFLVGTVG-QAF 469 Pseudomonas syr...
WP_013317956 407 RGEDRIDLSAFNk---N----HDLRFV-DNFSGKGN-EVVLNWDSQSHQTNMWLHLSGH------ETADFLVNIVG-AAL 470 Dickeya dadantii
WP_013317949 407 TGVDKIDLSALNt---G----NNLHFV-NQFSGSGG-EILLNWDSSASVSNLYLNLDNN------TSPEFLVKIVG-QVS 470 Dickeya dadantii
WP_013317950 409 KGIDKIDLSAFRn---E----GQLSFVqDQFTGKGQ-EVMLQWDAANSITNLWLHEAGH------SSVDFLVRIVG-QAA 473 Dickeya dadantii
WP_004236000 409 TGLDSIDLQGLNq---NsageKFIYFT-DEFTGAAG-AAELRYNEGLNLTELLINISGDp-----YNYDFRVDITG-QVN 477 Morganella
1KAP_P       406 SGQDKIDLSGLDafvnGg---LVLQYV-DAFAGKAG-QAILSYDAASKAGSLAIDFSGD------AHADFAINLIG-QAT 473 Pseudomonas aer...

1K7G_A       474 Q-SDIIV 479 Dickeya chrysanthemi
Q6D3F9       463 AaTDFIV 469 Pectobacterium atrosepticum
WP_046493259 530 TaNDFIF 536 Candidatus Hamiltonella defensa
1_pfamImport 209 TaNDFI- 214
2_pfamImport 217 TeADFIV 223
Q7N8R3       473 LeSDFIl 479 Photorhabdus laumondii subsp. laumondii TTO1
Q03023       474 Qa-DIVV 479 Pseudomonas aeruginosa PAO1
Q87ZU2       470 At-DIVV 475 Pseudomonas syringae pv. tomato
WP_013317956 471 QpSDVIV 477 Dickeya dadantii
WP_013317949 471 QtADFVV 477 Dickeya dadantii
WP_013317950 474 Qs-DIIV 479 Dickeya dadantii
WP_004236000 478 VhTDFIV 484 Morganella
1KAP_P       474 Qa-DIVV 479 Pseudomonas aeruginosa PAO1
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