Conserved Protein Domain Family
Whi5

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pfam08528: Whi5 
Whi5 like
In metazoans, cyclin-dependent kinase(CDK) dependent phosphorylation of the retinoblastoma Tudor suppressor protein (Rb) alleviates repression of E2F and thereby activates G1/S transcription. The cell size regulator Whi5 appears to be an analogous target of CDK activity during G1 phase.
Statistics
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PSSM-Id: 400712
View PSSM: pfam08528
Aligned: 74 rows
Threshold Bit Score: 36.9401
Threshold Setting Gi: 205831279
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EOA86221     158 QLKTRLSYAMVKVQNGWEKQSLDEL 182 Exserohilum turcica Et28A
Q2H6R4       197 iIRLRLGLASYKVRTGQTDVPLDRL 221 Chaetomium globosum CBS 148.51
CCE31714     147 ILRLRLGLASYKLRTGQTNVPLADL 171 Claviceps purpurea 20.1
EFX00111     173 ILKLRLGLASYKLRTGQVSVPLDQL 197 Grosmannia clavigera kw1407
XP_007279965 129 iLRLKLGLANYKLQTGQEDVPLDRL 153 Colletotrichum gloeosporioides Nara gc5
CDP32564     171 ILRLRLGLANYKVRTGQEDVSLDQL 195 Podospora anserina S mat+
Q0U942       199 NMRTRLKFALYKVRTNQEAKRGKDI 223 Parastagonospora nodorum SN15
XP_002175491 132 NLRLRLQLAMYKVQVNQPYSPLREl 156 Schizosaccharomyces japonicus yFS275
O42913       136 NLRLRLELAMYKVQVNQTFSPLQDL 160 Schizosaccharomyces pombe 972h-
CCA78048      51 QLRLRLSYAGYKAQNKLSSLPFSTL 75  Serendipita indica DSM 11827
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