Conserved Protein Domain Family
OapA_N

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pfam08525: OapA_N (This model is not part of the current CDD release)
Opacity-associated protein A N-terminal motif
This family includes the Haemophilus influenzae opacity-associated protein. This protein is required for efficient nasopharyngeal mucosal colonisation, and its expression is associated with a distinctive transparent colony phenotype. OapA is thought to be a secreted protein, and its expression exhibits high-frequency phase variation. This motif occurs at the N-terminus of these proteins. It contains a conserved histidine followed by a run of hydrophobic residues.
Statistics
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PSSM-Id: 518316
Aligned: 28 rows
Threshold Bit Score: 34.7222
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_012073825 171 VMQKLPHKHRRLFLAIAAAVVILAALlllkP 201 Actinobacillus succinogenes
WP_013319292  78 WMEPLPYFHRRCILILLCLLLLVLLW----P 104 Dickeya dadantii
Q6D140        73 WMEPLPLLHRRWILIAIAVLLIVLLW----P 99  Pectobacterium atrosepticum
P44415       129 ILQVLPAKHRRLFMAIFVLVILLIIFfalkP 159 Haemophilus influenzae Rd KW20
Q9CPE6       115 FLQILPQRHRRLFVALFGLILLLIIFfalkP 145 Pasteurella multocida
WP_014107880   5 tIKQLPKQHRWTLGCVALVLVSLILF----P 31  Glaciecola nitratireducens
Q6LUS0         5 kLTKLPRMHQILIALISAAVVMLILL----P 31  Photobacterium profundum
Q9KU93         4 LFNRLPWLHRVLITAFSAIIVFAIFFl---P 31  Vibrio cholerae
Q87LY7         4 IFVRLPLLHKVLIGFFSALIIIALFFl---P 31  Vibrio parahaemolyticus
WP_009847553   4 IFARLPILHRAFIAFFSAVIFIAIFLl---P 31  Vibrio
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