Conserved Protein Domain Family
MMR1

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pfam08505: MMR1 
Mitochondrial Myo2 receptor-related protein
Myo2p, a class V myosin, is essential for mitochondrial distribution, class V being vital for organelle distribution in S. cerevisiae. It is the myosin essential for mitochondrial distribution. The established mechanism for distribution of cellular components by class V myosins is that they interact with the cargo at the C-terminal tail domain and transport it along the actin cytoskeleton using the N-terminal motor domain. Cargo-specific myosin receptors act as the link between the myosin tail and cargo. Myo2 binds with MMR1 (mitochondrial Myo2p receptor-related 1), the receptor on cargo, via the C-terminal domain.
Statistics
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PSSM-Id: 400692
View PSSM: pfam08505
Aligned: 9 rows
Threshold Bit Score: 168.592
Threshold Setting Gi: 254578176
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003670498  62 KLNEINFSGTStttsqlQE--RRKSDT------------------FLPNSPVMLPL-----------FSNnnnpthgasa 110 Naumovozyma dai...
XP_003686226  56 KLNESTRTGRS------RQ--RRGSDI------------------MRSGSPIQFPS-----------IGS---------- 88  Tetrapisispora ...
EDO17047      56 KLNEMTRTGRS------SQ--RRNSDT------------------FRSTSPIRFPL-----------MNN---------- 88  Vanderwaltozyma...
CCK68693      54 KLNDRSRTGRG------RT--ANNNDLgirgasslnfgnkdygggFRSSSPIRFNI-----------LQN---------- 104 Kazachstania na...
XP_002495074  71 KLSELSRRGRS------RQ--RSNSDT------------------FRAASPTRLQF-----------FSN---------- 103 Zygosaccharomyc...
CCE91070      71 KLSELSRTGRS------RQ--RSNSDT------------------LRSNSPIRFQL-----------FNN---------- 103 Torulaspora del...
Q75BP0        53 KLAELTPGGGSasagspVSslRLPAQSl-----------------FRVGSPMRTSM-----------MSQ---------- 94  Eremothecium go...
CAR21560      54 KLTERGRSGRGrtv-----eaKTPTKL------------------LRSNSPIRAML------------NN---------- 88  Lachancea therm...
Q6FY87        50 KLSELSRTGRS------QQrsRRDSDT------------------LRSLSPLRLQFqntgganpgpnFSM---------- 95  [Candida] glabrata
XP_003670498 111 tannnaNKPTMFKREYFspATkHSNTtniskasLPLLSALMKgsivtNSSPTVEpsTRAIENDSIGTKSNN------TNG 184 Naumovozyma dai...
XP_003686226  89 ------AAPKMLKPEYL--NT-QNSA-------IPLLSTIMK-----QSSKTMD--TQKTDQDNTQNNQNSq----rENV 141 Tetrapisispora ...
EDO17047      89 ------IAPKMLKPEYI--AApQASA-------LPLLSTLMK-----HSSKNTKnmSQSNNQQKTSSNQNNnsipppSNS 148 Vanderwaltozyma...
CCK68693     105 ------AKPKMFKKEFIs----QPNN-------LPLFSTLVRga--sNAPSNTAanDVECNDGATSSIKSNpllddnL-- 163 Kazachstania na...
XP_002495074 104 -------APKMLKPEYV--SQ-QPSG-------MPLLSALIG-----NG--------------TTGSHT----------- 136 Zygosaccharomyc...
CCE91070     104 -------APKMLKPEYM--SQ-QPST-------LPLLSTLMK-------------------QSATGMASNSnk---eAKN 144 Torulaspora del...
Q75BP0        95 -------VPKMLRPEYMnvKAgWRDQlfktrnsIPKDGAVTVasaltSSAVPTMprELAHEAPLEGTS------------ 155 Eremothecium go...
CAR21560      89 -------PPKMLKPEYIgiSKlLNNNn-----sSRVGSAVTPsmiltSSKLNFGntKKASSEEVRQPTQTQeakkqvVAP 156 Lachancea therm...
Q6FY87        96 ------GAPKMLKPEFLqkSStSTST-------LPLLSALLM-----KT----GngKAGSQQQGSASNENNsqttsmSGF 153 [Candida] glabrata
XP_003670498 185 LKSKSKSKLTIKESLEQF-------------QQKLESSFKDRQPLSTPIHMEQHSEITNERES--------------NTS 237 Naumovozyma dai...
XP_003686226 142 ETRKLNTSIFAQLQESFInfnrqkekvenipVTTSKETHTEKEILTISKISKEEKHKPQSTMK--------------NNA 207 Tetrapisispora ...
EDO17047     149 EANPFQSRMTIKETLEQInvqkqryqtkeipEMSSRKFQDE---------------------R--------------TEK 193 Vanderwaltozyma...
CCK68693     164 ------PKLSIRETLEKI-------------QQHHQRLNAAKQKTPVVTNTVTTNKTEPILLK--------------SNS 210 Kazachstania na...
XP_002495074 137 ------SRLGIKETLEMFhrg--------lsNDSCPPQEQEKQQRQRHAQQSQS--------Q--------------PSQ 180 Zygosaccharomyc...
CCE91070     145 HQAEIATRAGIRETLKKYqd---------qqLQLSKQTDESKQQRQVDAKVEQQPKVPEAMIQ--------------PVP 201 Torulaspora del...
Q75BP0       156 -------------AWEQAgdgaqvaeasgktGQARPSAFNSYNKGSAAKHSSTHTPKVGNGSK--------------SKH 208 Eremothecium go...
CAR21560     157 PPTPTPVPQTEEPALPQAtta--------sqQMPPPSAQPRTQKHPEPAVHSHHGEKVPQPKQrhhsqmlshkdsrgSKH 228 Lachancea therm...
Q6FY87       154 EQVSM-----IKESLDQLrqev-----ivpkRNKNRDSTSTRRDRATTTKDETL--------A--------------VSD 201 [Candida] glabrata
XP_003670498 238 ERtnnddirdvkqqqivtEINEPSSTISSSSLLPLQ-MEptyERDTLNPLYSDYLKeai--------------------- 295 Naumovozyma dai...
XP_003686226 208 LR----------------KISHTESTLSGSTMHEQDgIS---EIESLEANNCNVEK------------------------ 244 Tetrapisispora ...
EDO17047     194 FR----------------NVSNTDSTLSGSTLN--DnISnniEPEPLKLEQKIQQE------------------------ 231 Vanderwaltozyma...
CCK68693     211 KS-------------------------SDMLIPPLE-------------------------------------------- 221 Kazachstania na...
XP_002495074 181 QS----------------NGSDRQS--SEATLNEEAdKQfrfQGETDNNNNNSNNNnnsnndnhanesnndklhiqnqnq 242 Zygosaccharomyc...
CCE91070     202 ER----------------NISESASAISGMTLCDKQrdpde--------------------------------------- 226 Torulaspora del...
Q75BP0       209 AR----------------ELS-VISCLSGKTLFEPDsLQpptGSISQPPSGSVYQF------------------------ 247 Eremothecium go...
CAR21560     229 AR----------------GLSSTSTAISGSTACELRt----eHAAALPTPGSVEEI------------------------ 264 Lachancea therm...
Q6FY87       202 DK----------------DARKVSDANSEKTLYEEQhLRk---------------------------------------- 225 [Candida] glabrata
XP_003670498 296 ----------------------peKPNVNVYRGNSMRMSSTAtTlytP-------LEEQHENQIQQDL-------VDMNG 339 Naumovozyma dai...
XP_003686226 245 ------------------------LPAVHPAKIVQKRIVSEH-A---T-------IQESELHEVPKDInvd-alpTDRNG 288 Tetrapisispora ...
EDO17047     232 ------------------------IPVTQASK-QNNRIVSHG-Sa-gN-------INQMEFDDIPQEInvd-clpTDRNG 276 Vanderwaltozyma...
CCK68693     222 ------------------------IDIMEKTDSPRDRIVSNTsTvcaPdnldsvvPLETKMQGRGENVean-nfaTDHNG 276 Kazachstania na...
XP_002495074 243 nqgditttatttttaadvdgtlkgNPSSPREN-PGTRMASNS-SvasS-------TMTVNFNDMSKEMeld-slpTDKNG 312 Zygosaccharomyc...
CCE91070     227 --------------------tmkvKATTPKPNEEEVRVISSS-SlvsS-------AVSIDFNNLPKELdld-alaSDKNG 277 Torulaspora del...
Q75BP0       248 ---------------------------------PSASPVSSS-SsanLay------------------------aVDENG 269 Eremothecium go...
CAR21560     265 -----------------------------ATKTPGYRFPSTT-StasS-------SSTFDLKEFPEALnlnfevpNDKEE 307 Lachancea therm...
Q6FY87       226 -----------------------qVPASHSKEVGSSRIFSTE-Ta-tS-------AKDVDSQQLRDGLdve-alpTDRNG 272 [Candida] glabrata
XP_003670498 340 FAKpyntlsthgnqlrnagmnenIRsgyNNSKNRYSFIS---STSTD-YDIDWYD 390 Naumovozyma dairenensis CBS 421
XP_003686226 289 FVQ--------------------LN---NHKNNRYSFIS---SASTD-FELDWYN 316 Tetrapisispora phaffii CBS 4417
EDO17047     277 FVQ--------------------LN---N-KGNRYSFIS---SASTD-FEIDWYN 303 Vanderwaltozyma polyspora DSM 70294
CCK68693     277 FLQyvrng----------nvpnyKKgssSSNVNRYSFIS---STSTD-YDApelf 317 Kazachstania naganishii CBS 8797
XP_002495074 313 FVE--------------------LV---DGKSNRCSFIS---SSSTD-IDADWYN 340 Zygosaccharomyces rouxii
CCE91070     278 FVQ-------------------------SDDFKRCSFIS---STSTD-YDADWYN 303 Torulaspora delbrueckii
Q75BP0       270 FVM-------------------------SNNKHRDSVLS---ATMEDrFWMDYQD 296 Eremothecium gossypii
CAR21560     308 FVL-------------------------ATQSKRSSYISsigSANED--DLNGWF 335 Lachancea thermotolerans CBS 6340
Q6FY87       273 FVQ--------------------IDh-kNINTNRYSFIS---ATSTD-YDMEWYE 302 [Candida] glabrata
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