Conserved Protein Domain Family
YGR210-like_G4
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pfam08438: YGR210-like_G4 (This model is not part of the current CDD release)
Obg-like GTPase YGR210-like, G4 motif-containing domain
This domain is part of the G domain found at the C-terminus of pfam01926 in archaeal and eukaryotic GTP-binding proteins. Members of this entry form a subfamily within the Obg family of GTPases and includes YGR210 from yeasts and its homologues from archaea. This domain seems to be necessary for the complete activity of the protein for binding of both adenine and guanine nucleotides, with a preference for guanine nucleotides. This domain contains the NKxD motif, known as the G4 motif.
Links
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Statistics
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PSSM-Id: 518263
Aligned: 123 rows
Threshold Bit Score: 76.4106
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_002140680  228 VLNKADKvnKNTSNNIIRIHEKYGds-cKIVVASSLAECFLKKMVKQSYIRYIEDDNDdsfsnkvtFVT-SNDsgklynk 305 
XP_004990426  761 ALNKADK----TLDYVDAVRATFPnd--lVVPMCAKLEWQLCTLRRKGLVDYQTGGSG--------AVVlKKDp------ 820 
XP_002950891  812 ALNKADM--ASSPDHIARVRQALPyd--pAVPVSAATERWLCNQRRAGRVSYADAAGD--------VVA-ISD------- 871 
Q9HP92        221 AANKMDT--PEAQANWAAITDDDEydhlEFVPVSAHAEQALTQADQGGVVDYRAGDDA--------FTI-VGE------- 282  Halobacterium...
WP_015301435  221 AANKMDT--PAAQDNWDEITTDPAyehlEFVPVSAHAEKALKNAKEQGVVEYTPGERD--------FAItTED------- 283  Halovivax ruber
Q5V136        222 AANKMDT--PAAQENWEPITEDPEyehlTFVPVSAHAEKALKNGNEQGVLDYRPGDEE--------FTV-TAD------- 283  Haloarcula ma...
5_pfamImport    1 AANKMDT--PAAQENFEEITDDPDydhlTIVPTSAHAEKALKNGDEQGVLDYLPGDSE--------FEI-VED------- 62  
WP_006054269  222 AANKMDK--PVAQENFEEITSDPEydhlTFVPASAHAEKALKNAEEAGIVEYEPGSSD--------FDI-VGD------- 283  Halogeometric...
WP_004044771  222 AANKMDK--PVSQENYEEITADSDyehlTFVPTSAHAEKALKKADEGGVVDYRPGDDD--------FDI-VGD------- 283  Haloferax vol...
WP_179260255  224 AANKMDT--PEAQENYEEITNDSDydhlTIVPCSAHAEKALKSADKAGVVDYRPGDAD--------FEI-TGD------- 285  Natrinema hal...

XP_002140680  306 ddekplkeLDDKLKNRLENIKDMV--LFRY------GVTGIKEAINAAV-ELLDIIPVYPVRN 359 
XP_004990426  821 -------pTTKKEEELMSNVHKAVdlLHTLassehlQGSGVLAVIDTAVhQLRPPLLVYPVTs 876 
XP_002950891  872 ---------SPELAQQLAKVRTAV--LSRY------GSTGAALALTCAV-AMRPPRPVFPVTD 916 
Q9HP92        283 --------PSDDQRAGLESIRE-F--VTEY------GGTGVQSAIEAALfDALGVKPVFP--G 326  Halobacterium salinarum
WP_015301435  284 --------LPAEQEAGLEQIRE-F--VDEF------DGTGVQQVLETATfDVLDLKAVFP--G 327  Halovivax ruber
Q5V136        284 --------LPEEKAAGLEQIRE-F--VTDF------GGTGVQQALETALfEELGAIAVFP--G 327  Haloarcula marismortui
5_pfamImport   63 --------VPGEKATALEQISE-F--VGEY------GGTGVQQAIETALfDELGSIAIFP--G 106 
WP_006054269  284 --------VSGEQEEGLEQIRE-F--LNAY------DGAGVQASLETALfDVMGAIAIFP--G 327  Halogeometricum borinquense
WP_004044771  284 --------VSDKQEAGLEQIRE-F--VTEF------GGTGVQQSLENALfDVMGAIAIFP--G 327  Haloferax volcanii
WP_179260255  286 --------ISSEQEAGLEQIRD-F--LADY------GATGVQAALEAALfDVLGVTPVFP--G 329  Natrinema halophilum
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