3ADB


Conserved Protein Domain Family
KTI12

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pfam08433: KTI12 
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Chromatin associated protein KTI12
This is a family of chromatin associated proteins which interact with the Elongator complex, a component of the elongating form of RNA polymerase II. The Elongator complex has histone acetyltransferase activity.
Statistics
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PSSM-Id: 400643
View PSSM: pfam08433
Aligned: 18 rows
Threshold Bit Score: 244.127
Threshold Setting Gi: 301598429
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3ADB_B    13 LIILTGLPGVGKSTFSKNLAKILSK--NNIDVIVLG-SDLIR------ESFP--VW-KEKYEEFIKKSTYRLIDSALKN- 79  Methanocaldococcus ...
Q86H29     3 LIVLSGPPCSGKTTRAKELYEHFTN--LGKKVIIIN-EESLLi-----NKNEg-YK-DSLTEKMTRGSLKGATDRNLSKd 72  Dictyostelium disco...
O46079     3 LVVITGLPASGKSTRARQLRDHFVE--RGRKVHLISeNEAVPka--gfGKNS--HTgDSQKEKVVRSDLKSEASRHLNQe 76  fruit fly
Q7Q9K5     3 LIVITGLPRSGKTSRAKELEKYFTEl-GKGPVHIVS-EADCIarsgcgVKES--FT-DTGKEKQIRASLKSEAMKLLTKs 77  Anopheles gambiae s...
Q5I0L7     3 LVVVCGLPSSGKSRRTEELRRALTG--EGRSVYVVD-DASVLg-----AQDStvYG-DSAGEKALRAALRAAVERRLSRq 73  Norway rat
Q6FME7     3 LVLMCGFPLSGKSTVARELAGYLRE--KGANVVVHS-DETLGhkgretREED--YN-DTHAERKLRNEIMSAVRRDLSRs 76  [Candida] glabrata
Q96EK9     3 LVVFCGLPYSGKSRRAEELRVALAA--EGRAVYVVD-DAAVLg-----AEDPavYG-DSAREKALRGALRASVERRLSRh 73  human
Q6LX62     2 LIILTGLPSVGKSTFSKAFSKKMAE--KNIDNIILG-TDLIR------ESFP--VW-KESYEEFIRDSNNYLIKEALENk 69  Methanococcus marip...
Q9LMH0     3 LVVICGQPCSGKSIAAVTLAETLKEseTKQSVRIID-EASFHl-----DRNQn-YA-NMPAEKNLRGKLRSDVDRSVSTg 74  thale cress
CAP38298   3 LIIVTGHPASGKSTIVDRLAQKFSE--SQKECQIIR-DDAYGs----fSRKN--YE-FANKEKDLRSWIRSEVQQNLTKn 72  Caenorhabditis brig...
3ADB_B    80 YWVIVDDTNYYNSXRRDLINIAKKYNKNYAIIYLKAS-----------------LDVLIRRN-----IERGEK------- 130 Methanocaldococcus ...
Q86H29    73 TVVISDSLNYIKGYRYELYCIARAAGTRLLVLYCNTP-----------------RDLAKKWN-----QERDQSv------ 124 Dictyostelium disco...
O46079    77 DLVILDAGNYIKGYRYELYCMSKVSRTTQCTVFTCIP-----------------QEEAWTFN-----SQRTAPdelpgds 134 fruit fly
Q7Q9K5    78 TLVIMDGTNYIKGYRYEIFCMSKNARTTQCTVHCAMT-----------------VEQRNARR-----EEIVQSsss---- 131 Anopheles gambiae s...
Q5I0L7    74 DVVILDSMNYIKGFRYELYCLARAVRTPLCLVYCIRPgwpsrglpvpgacessdPAVSVSWRpradyGEKTQAvgaveqr 153 Norway rat
Q6FME7    77 TIVIVDSLNYIKGFRYQLHCECKNSNTGFMLVHCMAT-----------------YADILKRD-----ENGEESp------ 128 [Candida] glabrata
Q96EK9    74 DVVILDSLNYIKGFRYELYCLARAARTPLCLVYCVRPggpiagpqvaganenpgRNVSVSWRpraeeDGRAQAagssvlr 153 human
Q6LX62    70 FSVIVDDTNYYNSKRRDLMNIAKECDTNYVTIYLKAP-----------------LNLLLKRN-----IERGQK------- 120 Methanococcus marip...
Q9LMH0    75 EIVIVDSLNSIKGYRYELWCIARAAGIRYCVVYCDVD-----------------EAHCRQWN-----KERSDRge----- 127 thale cress
CAP38298  73 KVVICDGLNYIKGYRYELFLAAKMSKTTYCVIQVTPS-----------------SDTCHWLN-----EQKPEGe------ 124 Caenorhabditis brig...
3ADB_B   131 --------------------------------------------------IPNEVIKKXYEKFDEPGKKYKWDEPFLIID 160 Methanocaldococcus ...
Q86H29   125 -------------------------------------------------aYSEKLLDELTNRFEVPNPKNRWDSPLFTLE 155 Dictyostelium disco...
O46079   135 erv--------------------------------------qpvdnsdvpYTRETFDALCQRYEEPQSNNRWDSPLVVVL 176 fruit fly
Q7Q9K5   132 ------------------------------------------------geLDAETFDALCQRYEEPQDTSRWDRPLFTVY 163 Anopheles gambiae s...
Q5I0L7   154 aisplanggvptavpkeldp----kdilpsnppavmtpeseksaepapcaFPPELLESLALRFEAPDSRNRWDRPLFTVV 229 Norway rat
Q6FME7   129 -------------------------------------------------rWGKELLDQLIQRFEEPDASNRWDSPMATVV 159 [Candida] glabrata
Q96EK9   154 elhtadsvvngsaqadvpkelereesgaaespalvtpdseksakhgsgafYSPELLEALTLRFEAPDSRNRWDRPLFTLV 233 human
Q6LX62   121 --------------------------------------------------IPNEVIKNMYEKFDTPGTKYAWDLPDITVD 150 Methanococcus marip...
Q9LMH0   128 ------------------------------------------------dgYDDGIFEDLVRRFEKPERRNRWDSPLFELY 159 thale cress
CAP38298 125 -------------------------------------------------rYSREIIDQLLMRYEKPDTKFRWEQPLFEVK 155 Caenorhabditis brig...
3ADB_B   161 ------TTKDIDF----------------------NEIAKKL-------------IEKSKEIPKFYVLEENKnKNNNISD 199 Methanocaldococcus ...
Q86H29   156 ------PQHTLPH----------------------ELLFKTL-------------FEVQELRPNYATQSQSL-SPANFVH 193 Dictyostelium disco...
O46079   177 ------PKDTLDM----------------------EAIYKAL-------------YESQPLPPNQSTYNAPL-GTTNYLF 214 fruit fly
Q7Q9K5   164 ------GGEEMEL----------------------ARIHSAL-------------YEQAPLPPNLATQNMPL-SATNFLF 201 Anopheles gambiae s...
Q5I0L7   230 g-----LEEPLPL----------------------AEIRSAL-------------FENRAPPPHQSTQSQPL-ASGSFLH 268 Norway rat
Q6FME7   160 spetllPTHKQLV----------------------DQVLLGIsdksssrngspspGPMNRLSQNNPTLLKAA-TGADFVR 216 [Candida] glabrata
Q96EK9   234 g-----LEEPLPL----------------------AGIRSAL-------------FENRAPPPHQSTQSQPL-ASGSFLH 272 human
Q6LX62   151 ------TTEKIDY----------------------NEILNEIle----------iNENKNLKIEEDKIPKSE-PVESDLV 191 Methanococcus marip...
Q9LMH0   160 psr-evIDKSSPV------------------------ILEAVtyltkt--vdsktQDVRILQPSIATQAARF-SEANSLY 211 thale cress
CAP38298 156 ig---kAEKALPTeidddmsidleypaprfanifdDEIVEWI-------------CNGTQLTENQSTQTVPL-APTNFLH 218 Caenorhabditis brig...
3ADB_B   200 KIDKETRKIVSEYIK----SKKLDKDK-----------------------------IKEVVELRKEFLKKIKk------X 240 Methanocaldococcus ...
Q86H29   194 ELETKTQEITSVISDalqsSMVGDYIKvpgtekrv--------------vihsklnLVELRNQRRQFYKFAQ-------L 252 Dictyostelium disco...
O46079   215 ELDKIVQAIIKEILGav-kIKAFGQLRipgsrnpv--------------kvatsmnALQLNRLRQKFITSTCha---sqT 276 fruit fly
Q7Q9K5   202 ELDKSTQTIIDQIAAar-kIGLDGPVEipqagmra--------------evpanmsVAQLNRHRRQFLNYVKmh----tN 262 Anopheles gambiae s...
Q5I0L7   269 QLDQATSQVLTAVMEaqksAVPGDLLTlpgttehl--------------rftrpltLAELSRLRRQFISYTKm-----hP 329 Norway rat
Q6FME7   217 LLDAKLTETVRIIVRecqaAQAIGGPQriivsedvrdinddrclfldipadapqltLPRLNRLKRQFVQMNKn------L 290 [Candida] glabrata
Q96EK9   273 QLDQVTSQVLAGLMEaqksAVPGDLLTlpgttehl--------------rftrpltMAELSRLRRQFISYTKm-----hP 333 human
Q6LX62   192 KIDSLTRNIVGNLIK----TGKIDKKD-----------------------------IKLLSEIRKSFLKDCKki----eS 234 Methanococcus marip...
Q9LMH0   212 ELDRATQEIINAIVEqqslGAAISRVTlgnelppi--------------eicrpigLPELRRLRRTFVKLMGqsslsgpP 277 thale cress
CAP38298 219 ELDRCTQDVVTVLLNaqrtAVRGQNLTipgasegsn-----------qvkflklrtLPELNRLRHQFVNMSKk------D 281 Caenorhabditis brig...
3ADB_B   241 EEVDADRVLKEFKDLLN 257 Methanocaldococcus jannaschii DSM 2661
Q86H29   253 HPPQPHLIADSFVDFLN 269 Dictyostelium discoideum
O46079   277 SPTPLEQVPHLFVQFIN 293 fruit fly
Q7Q9K5   263 VSSDISKIPAIFVQFLN 279 Anopheles gambiae str. PEST
Q5I0L7   330 NNENLPQLANMFLQYLN 346 Norway rat
Q6FME7   291 RDVDLERAAPLFVAYIG 307 [Candida] glabrata
Q96EK9   334 NNENLPQLANMFLQYLS 350 human
Q6LX62   235 EKLDFEKIEKDFLDYLN 251 Methanococcus maripaludis S2
Q9LMH0   278 LPTDADSAKRRFVDYLN 294 thale cress
CAP38298 282 PMSDKEKIINGFVDFLN 298 Caenorhabditis briggsae
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