4JRP


Conserved Protein Domain Family
Exonuc_X-T_C
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pfam08411: Exonuc_X-T_C (This model is not part of the current CDD release)
Exonuclease C-terminal
This bacterial domain is found at the C-terminus of Exodeoxyribonuclease I/Exonuclease I (pfam00929), which is a single-strand specific DNA nuclease affecting recombination and expression pathways. The exonuclease I protein in E. coli is associated with DNA deoxyribophosphodiesterase (dRPase).
Links
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Statistics
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PSSM-Id: 518245
Aligned: 83 rows
Threshold Bit Score: 125.729
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4JRP_A           215 RNKHKLMALIDVPQMKPLVHVSGMFGAWRGNTSWVAPLAW----HPENRNAVIMVDLAGDISPLLELDSDTLRERLYTAK 290 Escherichia...
WP_013388911     205 RDKDFVKSELSK--DELFLHIDFGYGYDRGYASIIYKIGDf--iNQGDKNAFLFIDILSDVENLEKMDFDEIKEYLYYSN 280 Ilyobacter ...
Q056Y2           212 KKKYISSFLLNNIN-KPFFYISSFFGSINYNFGCIMYIGL----HPLYKNNIVIFDLSSDFKKIFNLYKKYSTCLISIK- 285 Buchnera ap...
Q89A43           212 RTKKAILTLIDVNSLNPIVYISRFFGVVNRYISYIVPILW----HPINSNILVSIDLSQDVQKILNFFKRNSILNVNYK- 286 Buchnera ap...
eebua:ZICARI_019 207 RNKKNIIKNILFK-KKVFLYLSNKYPFFEKEIFILLPLFI----DNKNKNKLICLNINSNFNNFFDFKKKYNFKKINNY- 280
Q5QZ62           210 RRKQKLLNLFNWQAPEPLAHVSGFYGTANRYLSAILPLGF----HPKQNSNVVAWDLRVPPMDFADKSVEELTELTYTSR 285 Idiomarina ...
WP_013607747     213 RAKTQVKKVVQTPFGEPVLYTAAFFSKNEGCSRLITPITH----MKSNANAIICFDLSKDVAPLLQATEETLLKt----- 283 Sphaerochae...
WP_013255611     206 RIKDHARQLIDLHKRRPFLHTSAMLSNEYGYTSILAPVAP----HPANQNAILCFDLRQDPEPLIERSVDELRRLIFAPS 281 Sediminispi...
jgi:Spiaf_1282   202 RSRDKVRSLLDIGVRRPVLHTDGIHTRQAGCTTAVAPVGV----NPENPKAVIAADLRYDPTPIIELPTEEVRRRIFTSS 277
WP_024266805     206 RKKDELRKLFNLNSRPALVHSSPLLTRKEGATTLICPLGVpgegARQGRDTMLCADLRYDPSRILDLSVEEIRKRVFLP- 284 Salinispira...

4JRP_A           291 TDL--GDNAAVPVKLVHINKCP-VLAQANTL--RPEDADRLGINRQHCLDNLKILREN-PQ-VR--EKVVAIFa----EA 357 Escherichia...
WP_013388911     281 EKLeeIGITRPGLKQIRINQSP-LVIPYNNLreKPKFLEEISVNLKYKMEKIKKLSAKrK------EEFLNVF-----TR 348 Ilyobacter ...
Q056Y2           286 ------KLFNVGIKVVSISKSPlFFS-YNSV--SLKHCIRLNIDYLKCQKNFFLLKNN----FLikNWIISCF-----SY 347 Buchnera ap...
Q89A43           287 ------EIFLMGIRFIYVNRCP-ILIPTNVI--RMKDRIRLRINYKLFQNNLVLLRKN----IFlkKKLKK-FlcsiaEA 352 Buchnera ap...
eebua:ZICARI_019 281 ------------IKIININKYPiIFFNIKKIlkKIN----FKINFNLIKKNITKINNNiKLiLNiyKKFNYNY------- 337
Q5QZ62           286 RELeeQGLQKSGIQNIHLGRCP-FLAPIKTI--SAEAADSAALDTAALETNAKWLQENsD--FR--DKLMQVFe----QT 354 Idiomarina ...
WP_013607747     284 -----EGVFTLSI-----NKCP-FVSPLNVL--TDQLAIKLGIDKELALFRHQQIVNq-TK-LL--MTARNIE-----EK 341 Sphaerochae...
WP_013255611     282 EELs-LEESRIRLIPIHINRSP-VLAPLSTL--DPDTAKRLGLDVTLCGKRAAKLAEAsL--LT--QKIMEVF-----RR 348 Sediminispi...
jgi:Spiaf_1282   278 EILapE--QRIHVTEIHENRSP-VLTPVAAL--DPESSRRLDIDIELCTERARMLYRNtL--LI--QKFQKVYg----ER 344
WP_024266805     285 SAMedETHRRYPVYSIKINRAP-FVAPLNSL--KPERADALNIDIQKCLDNRDTLLRn-QD-IT--AKIRQVFn----DP 353 Salinispira...

4JRP_A           358 EPFtPSDNVDAQLY-----NGFFSDADRAAMKIVLETEPRNLPAL----DITFV--D-------------KRIEKLLFNY 413 Escherichia...
WP_013388911     349 EKDkVKIDADLDIY-----GSFASQWDKKEMAAMHRENYQYIP--------KFK--D-------------KKYKELYFRF 400 Ilyobacter ...
Q056Y2           348 KKKeKINDIDLMLY-----NNFFLNSDRCLLSFIHKNEPKKWMGW----SANFL--D-------------NRIKKLFFRL 403 Buchnera ap...
Q89A43           353 PKYn-GSNVDLKMY-----NSFFSYIDNNVIKNIHSTLPKRI-------KINFMkyD-------------NRINQLFILF 406 Buchnera ap...
eebua:ZICARI_019 338 -KYkKILNINFDLYn----NFFISLNDKYNIKIIKKLNINKIH------NKKFYfyN-------------NNIKILCFFY 393
Q5QZ62           355 KEFaPRTDVDHQIY-----DGFFSPQDKKHMEIIRSSEPHQLAGL----ELDFQ--D-------------KRMPALLFRY 410 Idiomarina ...
WP_013607747     342 --YeGVDDVDFQLY-----DRFFGDADQKRFNLIRQAEPKDKLSL----HLDFE--D-------------NRVAPLLFRH 395 Sphaerochae...
WP_013255611     349 DEAeIRRDPELEIYs----GGFFSDADRQRMERFRELSPEAMLKR----RGDFY--D-------------RRLPELAWRF 405 Sediminispi...
jgi:Spiaf_1282   345 PAReTPEDPELMIYgggpfGGFFADEDKKLFEAIRHAEPGQLLSI----EPKSH--D-------------QRIPVLFRRY 405
WP_024266805     354 PSGsLPDDPDYQIY-----GGFFADGDREQFPFIHRSMEELLSMDdksrETGIR--EfisgvqrmnltqkERVSKLVSRM 426 Salinispira...

4JRP_A           414 RARNFPGTLDYAEQQRWLEHRRQVFTP-E------F-LQGYADELQMLVQQY--ADDKEKVALLKALWQY 473 Escherichia coli K-12
WP_013388911     401 IGRNMPEILTEDEMSEWKRHCYKCISN-Ereg--fqnIDSLKNEILELEKKY--RGEKEKIKILKDIKIY 465 Ilyobacter polytropus
Q056Y2           404 KARNFIKLLNFNEIKKWQFYCKNKINF-Ik-------LEEYFEKIKKFQLKF--NKNDKNFILLEDLFKY 463 Buchnera aphidicola BCc
Q89A43           407 LARYRPDMLDYSEKYFWIQRYLNIFSY-An-------IQKYENKILKLIVKY--KNHVRNVQLLEELFEY 466 Buchnera aphidicola s...
eebua:ZICARI_019 394 KLKKYKKYISNFEKKIWIKYCKINLLKny-----nN-ELNFFEKLFYIKKKYlkCSNKYKKKILYFLINY 457
Q5QZ62           411 RARNYPSTLSDKELNKWRLFCQQRLIEpPeg--llS-AEGFALKLEDLANQH--QEDAHKLRLLKSLYDY 475 Idiomarina loihiensis
WP_013607747     396 VARNWSEVLTDEQKRKWRSFCANRTLN-PpgsikmN-WNFFKRKIEEKLAST--ETSAEEKRVLADLKAY 461 Sphaerochaeta globosa
WP_013255611     406 VCRNHSEILDENERKKWKSFCAGRLLFpPer--liNdFAFFKRKVKELSGDT--NLPAGDKKIIKKLAEW 471 Sediminispirochaeta s...
jgi:Spiaf_1282   406 VWRNAWEALDQAERDRYRAFCAKRLLQpPvts-glT-RETYEKRIKQLWESP--GLDARGTVVLKSLRDY 471
WP_024266805     427 LGRNFGSQLRGKAAQSWKEFCQNRLIFplln-earD-IHSFRREIEKLQSRP--GLQVRDKIVLKELLEY 492 Salinispira pacifica
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