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FBD This region is found at the C-terminal of F-box domain containing proteins (pfam00646) from plants; its precise function is unknown, but it has been associated with nuclear processes. Proteins in this entry are involved in the ubiquitin-proteasome pathway. They function as components of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes. They have a F-box domain at the N-terminal (pfam00646). AtMIF1 (also known as F-box protein AT3G62230) from Arabidopsis, physically interacts with MYB domain protein 5 (MYB5), which results in MYB5 degradation representing a new regulatory pathway, 26S proteasome-AtMIF1-MYB5 that regulates oil content of seeds, increasing their oil content without affecting plant growth. This domain has a LRR-like fold. |
Jiyao W et al.(2023). "The conserved domain database in 2023.",