5T0C


Conserved Protein Domain Family
Rpn3_C

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pfam08375: Rpn3_C (This model is not part of the current CDD release)
Proteasome regulatory subunit C-terminal
This eukaryotic domain is found at the C-terminus of 26S proteasome regulatory subunits such as the non-ATPase Rpn3 subunit which is essential for proteasomal function. It occurs together with the PCI/PINT domain (pfam01399).
Statistics
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PSSM-Id: 518223
Aligned: 60 rows
Threshold Bit Score: 69.5394
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5T0C_AV      464 DIYSTREPQLAFHQRISFCLDIHNMSVKAMRFPPKSY--NKDLESAEERREReqqDLEFAKEMAE--DDDD 530 human
XP_006684642 403 DIYSTKLPQDEFDQRIKFCLSLHNDSVKSMRYPSENL--KDDTKNSETFED----EFELLKAIEE--GDLD 465
XP_002770091 418 DIYSTKLPQGEFDQRIKFCLSLHNDSVKSMRYPSDNNk-LDSNKNSLESKEE---EIDLLKAIEE--GDLD 482
XP_001487379 403 DVYSTKLPQDDFDQRIKFCLSLHNDSVKSMRYPSADNr-SDINKHNLAAKED---EMDLLKAIEE--GDLD 467
XP_001383755 414 DVYSTKLPQNEFDQRIKFCLSLHNDSVKSMRYPNDSDdkADAVKN--ESKED---EMDIMRAIEE--GDLD 477
XP_007372335 414 DVYSTKLPQTEFDQRIKFCLSLHNESVKAMRYPNDND--KQNVTKEVEASE----EIELLKAIEE--GDLD 476
XP_036664041 410 DVYSTRLPQTEFDHRIKFCLSLHNDSVKSMRFPNDDD--KQPVNKEVEPSD----EVELLKAIEE--GDLD 472
XP_001526739 412 DVYSTNLPQAEFDQRIKFCLSLYNDSVKSMRFPDDNE--NKAITKDAEPSD----EVELLKAIEE--GDLD 474
Q75D59       433 NVYATMQPQQAFDDRINFVNQLHDECVMAMRYPGSREkkKNVKTDD---HEGe-iDPDIMD-LSDygSDIE 498 Eremothecium gossypii
Q6CR95       436 NVYSTKQPQQVFDERIRFVNHLHSDYVTGMRFPDSREedNSKKLSDESLETTm--DLNSMN-LSDfdSDLD 503 Kluyveromyces lactis
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