6CUD,8WPL


Conserved Protein Domain Family
TRP_2
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pfam08344: TRP_2 (This model is not part of the current CDD release)
Transient receptor ion channel II
This domain is found in the transient receptor ion channel (Trp) family of proteins. There is strong evidence that Trp proteins are structural elements of calcium-ion entry channels activated by G protein-coupled receptors. This domain does not tend to appear with the TRP domain (pfam06011) but is often found to the C-terminus of Ankyrin repeats (pfam00023).
Links
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Statistics
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PSSM-Id: 518199
Aligned: 30 rows
Threshold Bit Score: 84.1681
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6CUD_A        182 CKCGDCMEKQRHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEF 243  human
XP_009017364  181 CMCVECMNNRETDSLKRSKSRLNTYKALVSPAYMALSSPDPIMTTFQLRQEMKKLAQVEKEF 242 
2_pfamImport    1 CQCADCTHMRRNDALNYCLSRLNAYKGLASPVYLSLITADPVRLALKLSHELTRMADVEKEF 62  
4_pfamImport    1 CQCKTCSEQRRHDSFSHSQSRINAYKGLASPAYLCLSSEDPVMAALELSNELAVLANTEKEF 62  
XP_006629229  245 CKCNECMEKQKKDSFSHSRSRINAYRGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEF 306 
XP_009009132  159 CSCSKCRKETFEDSLRYSLQRIQIFRALSSPAWISLTSFDPVLTAFRLSWELEHLAMKENEF 220 
EFO98458      193 CICETCDRERLYDSLQYSLKRINTYRALASPAYMSLTSSDPINEAFKLSWDLQKLAFEEHEF 254 
XP_009029465   46 CTCPECEMMEDV-SLIEAKTRYTEFKCLASPPYVILSTFDPLLYMFRLNSVLKAESKTEPEF 106 
XP_009029493  186 CDCEDCKNISER-SLIEALSRQHEYRALASSAYITVSSIDPIIHTFRLYSDLLEESELDPEY 246 
XP_029687673  174 CDCLECRNGRQYDLLKFSLSRINTYRGIASRAYLSITSDDPMLKAFGLSKELRKLSQKEPEF 235  torafugu
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