Conserved Protein Domain Family
PRD_Mga
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pfam08270: PRD_Mga 
M protein trans-acting positive regulator (MGA) PRD domain
Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This corresponds to the PRD like region.
Links
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Statistics
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PSSM-Id: 429889
Aligned: 3 rows
Threshold Bit Score: 234.016
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q8DNN5 193 SEPLSQLL---ELVYKETSFPMNLSTHRMLKLLLVTNLYRikFGHFMEVDKDSFNDQSLDFLMQAEGIEGVAQSFESEYN 269 Streptococcus pneumon...
Q8DYW7 170 EVMIRDFIeysNFKGCDYDLKDLSEEYYYFYILVNLVWKR--KEYKVEIPQTESFNQLKKSILYMELSKAAQKSIAIHLG 247 Streptococcus agalact...
Q8DP24 182 EEDLTEFA---DFFYKITNYPMRFSIYRMYKLMIAISIHRvkNGHFIDLPNHFY-KEYYPLLKSIPNFQETLAYFSKHFG 257 Streptococcus pneumon...

Q8DNN5 270 ISLDEEVVCQLFVSYFQKMFFIDeSLFMKCVKKDSYVEKSYHLLS--DFIDQISVKYQIEIENKDNLIWHLhntAHLYRQ 347 Streptococcus pneumon...
Q8DYW7 248 IELNEGLLDYLYLVFCISDGPLF-SNRDDININEEFIFASYKISKskAFKNFCGRLLGREFIDSQHFKDIN---AYFLRH 323 Streptococcus agalact...
Q8DP24 258 LEMTPDTIAQIFISFLQNDIFLDpQEFFNSLEDNSQARYSYQLLS--QILEGLSKQYKITFTNHDELIWHLhntAFFERQ 335 Streptococcus pneumon...

Q8DNN5 348 ELFT-EFILFDQKGNTIRNFQNIFpKFVSDVKKELSHYLETLEVcsSSMMVNHLSYTFITHTKHL 411 Streptococcus pneumoniae R6
Q8DYW7 324 FICYcYYFIPDFYFLNTSRLSYSK-DLYHLLDKGLADIFNLKGG--NLTFSKHETVLLTMQLSNL 385 Streptococcus agalactiae serogroup V
Q8DP24 336 EIFS-TPILFEQKALTIKKFEVYFpDFMGSARQELAQYRQAIGQhdHPEQLEHLMYTILTHAENL 399 Streptococcus pneumoniae R6
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