Conserved Protein Domain Family
PE-PPE

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pfam08237: PE-PPE 
PE-PPE domain
This domain is found C terminal to the PE (pfam00934) and PPE (pfam00823) domains. The secondary structure of this domain is predicted to be a mixture of alpha helices and beta strands.
Statistics
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PSSM-Id: 369775
View PSSM: pfam08237
Aligned: 21 rows
Threshold Bit Score: 208.34
Threshold Setting Gi: 119955068
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Mvan_1238  75 ADPDLVGipYPA---------SFWP-----LSFLpgwcvpgrceKWDVSVGEGTENLLAALSPFL--------------- 125 Mycolicibacter...
P9WHX5        242 TTPEVVS--YPA---------TIGVls-gsLGAV----------DANQSIAIGQQMLHNEILAATa-------------- 285 Mycobacterium ...
O07801        106 ATRHVVS--YPG---------SFWPvt--gLNSP----------TVGSSVSAGTNNLDAAIRS----------------- 145 Mycobacterium ...
Q9CC62         78 VNRKLID--YPArapf-ryvpTFLVpg--pRDEV----------TIGEAIAVATKNLNQAIHR----------------- 125 Mycobacterium ...
O50440         81 AKHDLID--YPAgaafswwptMLLPpg-shQDNM----------TVGVAVKDGTNSLDNAIHH----------------- 130 Mycobacterium ...
Q73XS5         74 QQRQIVR--YPAgqvq-ghvlERLFpgigkLDESfpglg-mngpSVGESVAEGIDNLDAAIRT----------------- 132 Mycobacterium ...
jgi:Mvan_1011  77 SPYEQIL--YNA---------GFWPfsrggFADP----------TFNKAVSQGVESLEAEQLA----------------- 118 Mycolicibacter...
jgi:Mvan_4726  79 CSLVATY--TPA---------QIRFvn--gIFDM----------TYDESVAVGQANLNDCIQGSDctatlapy--setgp 133 Mycolicibacter...
jgi:Mvan_4815  84 TNAVAVY--TPE---------QFFP-----IGQL----------TFARSVAEGLVNLHRCLGAETdcvfnddpairphav 137 Mycolicibacter...
SUA33185       21 YNAVAVI--TPA---------QFNSge-pgDTSL----------TFDDSVAAGAGKLATCIESGDecdined----lgsd 74  Mycolicibacter...
jgi:Mvan_1238 126 ---AAESaeeVFVFGYSQGGAVVANALTQLTDLSEDVK---SRLNVVTIGGIENP----DGGMWQRLAWlrYLLGEpvpi 195 Mycolicibacter...
P9WHX5        286 ---SGQP---VTVAGLSMGSMVIDRELAYLAI--DPNAppsSALTFVELAGP-------ERGLAQTYLPvgTTIPI---- 346 Mycobacterium ...
O07801        146 ---TDGP---IFVAGLSQGTLVLDREQARLAN--DPTApppGQLTFIKAGDP-------NNLLWRAFRPg-THVPI---- 205 Mycobacterium ...
Q9CC62        126 ---GTEP---AAVVGLSQGSLALDTEQEQLAT--DPTApppDQLTFNTFGDPSGYhgfgKSVLASIFRPg-DYIPL---- 192 Mycobacterium ...
O50440        131 ---GTDP---AAAVGLSQGSLVLDQEQARLAN--DPTApapDKLQFTTFGDPTGRhafgASFLARIFPPg-SHIPI---- 197 Mycobacterium ...
Q73XS5        133 ---TGRP---GTAIGLSEGAFVVDGEQARLAN--DPTApppNTLNFATFGDPIGRhafgQSFLTAMFGVg-SVVPA---- 199 Mycobacterium ...
jgi:Mvan_1011 119 ---AGDM-----IFGFSHGAVVASRYKATH-----------TGNTYILVGNPSRP----NGGIMQRFKG--ITVPI---- 169 Mycolicibacter...
jgi:Mvan_4726 134 htvADST---YVIYAYSQSATVAANQKLQLIA--HPVA---STVSFLLVANPNRP----DGGILERFVG--AYIPL---- 195 Mycolicibacter...
jgi:Mvan_4815 138 aprAGDA---MMAFGYSQSAVIASLAKLDLIQRYQPGD---PSVSFMLVANPMRP----NGGILMRLHGw-PTIPI---- 202 Mycolicibacter...
SUA33185       75 rpaPGDN---LVVFGYSQSAAIATLEKARLAALYPYGEg--PDVSFILTANGNRP----NGGFLARGPKg-VTIPLgtpg 144 Mycolicibacter...
jgi:Mvan_1238 196 LDLSFDPAMPTDT------G--IP----TTTIGFEYDPV-VYAPLYWGNPFAIVNMIAA-FDTVHGyylapnqNNDNPMp 261 Mycolicibacter...
P9WHX5        347 --AGYTVGNAPES------Q--YN----TSVVYSQYDIW-ADPPDRPWNLLAGANALMG-AAYFHD-------LT-AYAa 402 Mycobacterium ...
O07801        206 --IDYTVPAPAES------Q--YD----TINIVGQYDIF-SDPPNRPGNLLADLNAIAAgGYYGHSa-----tAF-SDPa 264 Mycobacterium ...
Q9CC62        193 --IDYTMPQRMDS------Q--YD----SNRVVAAYDGL-SEFPDRADNLLAQLNCFAG-GAISHTp-----sGF-FNPe 250 Mycobacterium ...
O50440        198 PFIEYTMPQQVDS------Q--YD----TNHVVTAYDGF-SDFPDRPDNLLAVANAAIG-AAIAHTp-----iGF-TGPg 257 Mycobacterium ...
Q73XS5        200 --LDYTMPPPYES------Q--YD----TNRFVAAYDSI-ADFPDRPDNMFALANTLMG-LATGHTa-----vAF-TNPs 257 Mycobacterium ...
jgi:Mvan_1011 170 VDFTFSGATPDNG---------DL----TYDVVRQYDGW-ADFPTYLWNPIAVANAVVG-ILLVHG-------NTQFELt 227 Mycolicibacter...
jgi:Mvan_4726 196 LGITFNGSTPTFS------P--QPrpltTVDVARQYDGW-ADFPTNPLNLLADLNAIMG-TILLHP-------NY----- 253 Mycolicibacter...
jgi:Mvan_4815 203 LEIPFPGASPTDSavlpdgRhvYP----TVDVARQYDGLgGDFPVRPLNLVATVNALLG-YALLHgs------------- 264 Mycolicibacter...
SUA33185      145 GGVTFNGSTPTDTq--------YS----TIDVAIQYDGW-ADQPINPANLLAVANANAG-QRLLH--------PHYADY- 201 Mycolicibacter...
jgi:Mvan_1238 262 ygytdatlapqLdcglsPANCR-----TDSFGNSYIMIPATSLPLTDLVRSL-AdslgigwLAEPFIDLAEPVLREFVDL 335 Mycolicibacter...
P9WHX5        403 p---------qQ-----GIEIAav-tsSLGGTTTTYMIPSPTLPLLLPLKQI-G-------VPDWIVGGLNNVLKPLVDA 459 Mycobacterium ...
O07801        265 r---------vA-----PRDITtt-tnSLGATTTTYFIRTDQLPLVRALVDMaG-------LPPQAAGTVDAALRPIIDR 322 Mycobacterium ...
Q9CC62        251 d---------vP-----PQNIRtt-vnSRGAKTTTYLIPVNHLPLTLPLRYL-G-------WSDALVDQIDAVLQPKIDA 307 Mycobacterium ...
O50440        258 d---------vP-----PQNIRtt-vnSRGATTTTYLVPVNHLPLTLPLRYL-G-------MSDAEVDQIDSVLQPQIDA 314 Mycobacterium ...
Q73XS5        258 m---------vP-----PQNIRtt-inSRGAKDTTIMIPEKHLPLVMPLRYI-G-------IDENTLNKLDAILTPRVNA 314 Mycobacterium ...
jgi:Mvan_1011 228 a---------aDleaakATGDPdyyqfDADSNTHYYVVKTYPVPLLMPVAWL----------PDPIIAALDAPLRWFIEL 288 Mycolicibacter...
jgi:Mvan_4726 254 ------------------SDAGtpqlqGQYQDSTYYLIPAPITPVLVPLTWV-Pi------VGKPLAIALDPAVRVLVEM 308 Mycolicibacter...
jgi:Mvan_4815 265 ----------aV-----DIPLAqarfqGRQGDTGYYLVETDLVPLLQPFAFF---------VPRPILKAIDAPLRVVIED 320 Mycolicibacter...
SUA33185      202 -----------------SLGSPgiidqGQYGDTRYLMIPTDTLPLLYELSQT-Pi------VGSFLADVLDAPLRVLVES 257 Mycolicibacter...
jgi:Mvan_1238 336 GFD 338 Mycolicibacterium vanbaalenii PYR-1
P9WHX5        460 GYS 462 Mycobacterium tuberculosis H37Rv
O07801        323 AYQ 325 Mycobacterium tuberculosis H37Rv
Q9CC62        308 AYA 310 Mycobacterium leprae
O50440        315 AYa 317 Mycobacterium tuberculosis H37Rv
Q73XS5        315 GYS 317 Mycobacterium avium subsp. paratuberculosis
jgi:Mvan_1011 289 AYD 291 Mycolicibacterium vanbaalenii PYR-1
jgi:Mvan_4726 309 GYD 311 Mycolicibacterium vanbaalenii PYR-1
jgi:Mvan_4815 321 AYD 323 Mycolicibacterium vanbaalenii PYR-1
SUA33185      258 GYD 260 Mycolicibacterium smegmatis
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