6AGB


Conserved Protein Domain Family
RNase_P_pop3

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pfam08228: RNase_P_pop3 
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RNase P subunit Pop3
This family of fungal proteins form a subunit of RNase P, the ribonucleoprotein enzyme that cleaves the leader sequence of precursor tRNAs to generate mature tRNAs. The structure of Pop3 has been assigned the L7Ae/L30e fold. This RNA-binding fold is also present in human RNase P subunit Rpp38, raising the possibility that Pop3p and Rpp38 are functional homologs.
Statistics
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PSSM-Id: 400504
View PSSM: pfam08228
Aligned: 5 rows
Threshold Bit Score: 158.443
Threshold Setting Gi: 74582454
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6AGB_C  14 KRRQVYKPVLDNPFTNEAHMWPRVHDQPLIWQLLQSSIINKLIHIQSk---ENYPWELYTDFNEIVQYLSgaHGNSDPV- 89  Saccharomyces cerevis...
Q753G4  13 KKKQVYKPILDNPYTNEAELWPHVREQSVVVELLLNAVLRPLRHAREl--gGAPPFEVHTGYNDVMERLG--CAESGTA- 87  Eremothecium gossypii
Q6CTJ8  13 KRRQVYKPILENPFTNEAKLWPHVTDQKLVLELLEEKVLKRWKLLQDm---GNNEESITVGFNEIVDLLS---HGKDEY- 85  Kluyveromyces lactis
Q6FQW2   3 KRGGRVIPVLEDPYSNEK--WPYCTPE--QLELLDTYMDKSVLRALKns-kPGEETGVVFDIAEILRVLQ---SESADV- 73  [Candida] glabrata
O74450   7 KVKQTVKLVLRNPLSIS---WPIVDAN------TQEKLAQTLVQWLPashkDILDSKLTVGLNSVNELLErcCQNAKDVt 77  Schizosaccharomyces p...
6AGB_C  90 ----CLFVCNKDpDvPLVLLQQIPLLCYMAPMT----VKLVQLPKSAMDTFKSV----SKY---GMLLLRCDDRVDKKFV 154 Saccharomyces cerevis...
Q753G4  88 ----LLFVCTRDgT-PAVLLSQVPLAAHVSALD----VAVVQLPCGTLARFDEHlpgtPHD---GMLLVPETAAVDPAFV 155 Eremothecium gossypii
Q6CTJ8  86 ----MLFVCNKD-L-PSVLISQLPILCETSDHT----VTLVQLPRLSSAKFDDAf---RDVvhdGMCLVRTHAHYQ-DFA 151 Kluyveromyces lactis
Q6FQW2  74 ----YVLALWND----SMLMRQLRLLVAVKN------VPLIPINKKINNKLLEHvg-dSYA---DVLLLKKTASLDQSLA 135 [Candida] glabrata
O74450  78 qpavVFILHDQD----SMLVTHMPQLVANANFYgsskCRLVPLGFSAQALIAKKlg-lSRA---GAIAVQDDSPLWKYLK 149 Schizosaccharomyces p...
6AGB_C 155 SQIQKNVDLLQFPWLNA 171 Saccharomyces cerevisiae S288C
Q753G4 156 QKVRASVERRAIPWLEP 172 Eremothecium gossypii
Q6CTJ8 152 KMISTKVEPLSIPWLHS 168 Kluyveromyces lactis
Q6FQW2 136 NLLDS-IEQPPTPFLEP 151 [Candida] glabrata
O74450 150 DLVMN-IEEPQARWLSE 165 Schizosaccharomyces pombe 972h-
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