8Q84


Conserved Protein Domain Family
DASH_Hsk3
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pfam08227: DASH_Hsk3 (This model is not part of the current CDD release)
DASH complex subunit Hsk3 like
The DASH complex is a ~10 subunit microtubule-binding complex that is transferred to the kinetochore prior to mitosis. In Saccharomyces cerevisiae DASH forms both rings and spiral structures on microtubules in vitro. This family also includes several higher eukaryotic proteins. However, other DASH subunits do not appear to be conserved in higher eukaryotes.
Links
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Statistics
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PSSM-Id: 518130
Aligned: 41 rows
Threshold Bit Score: 39.0695
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
8Q84_Q         6 QRQYNQLAHELRELQTNLQETTKQLDIMSKQCNEnlVGQLGKVHGSW 52  brewer's yeast
EDO19611       6 QRQYARLAEQLELLQHNLLNTTEHLDVMSRQCNNniVDQLGKVSASW 52 
XP_003670256   6 QRQYAHLAQQLKLLNQNLEKTTEELNIMSSQCNKniVGQIGKIHSSW 52 
XP_022462523   6 ERQYTYLANQLQSLQSNLQTTRDELEMLSLQCDKnlVGQLGKINASW 52 
XP_003957074   6 kRQYAYLAQQLQQLQTNLQTTKDEMSVLSSQCNKniVGQLGKINASW 52 
NP_001138275 179 AREKNHLILENETLCRNLSHTAEQLERMSIQCDVwrSKFLASRVMAe 225
Q753W8         6 RRHYSQLSQQLQLLQKNLEATTQHVETMSVQCNEhlVNKLGKIQASW 52  Eremothecium gossypii ATCC 10895
Q5KFQ3         8 QRHYSALASRIRSLHANLAETEGLLDMMTHQLDA--TAKIGVHCGSQ 52  Cryptococcus neoformans
XP_003686553   6 QRQYSRLAEQLSQLQDNLEEATQHLDTMSKQCNTniINQLGKLHASW 52 
XP_002999405   5 QRQYARLAAHLKQLRENLDETTAQVEIMANQSNM--ITKLGAVQAST 49  Kluyveromyces lactis
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