4BL0


Conserved Protein Domain Family
Mad3_BUB1_II

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pfam08171: Mad3_BUB1_II 
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Mad3/BUB1 homology region 2
This domain is found in checkpoint proteins which are involved in cell division. This region has been shown to be necessary and sufficient for the binding of MAD3 to BUB3 in Saccharomyces cerevisiae. This domain is present in BUB1 which also binds BUB3.
Statistics
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PSSM-Id: 400476
View PSSM: pfam08171
Aligned: 16 rows
Threshold Bit Score: 71.1518
Threshold Setting Gi: 74610036
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4BL0_E          7 KTSIYAD----------------------QKQSNNP--VYKLIN---TPGRKPERIVFNFNLIYPENDE---EFNTEEIL 56   baker's yeast
Q6FQ60        247 KIPIFHDsesp---------------eknSKSNKSQ--VLKVVE---MKGKKPQKIVCNFKLLFPDDSQ---EYCIEEIL 303  [Candida] gla...
CCF60444      241 KLNVFNDnnndnnnnni---nsntttnnnNNNDNIP--VYKIVN---IENRKPEKIDCNFDLIYNSS-----EFNFDQIL 307  Kazachstania ...
XP_003673647  292 KLPVFTDnii----------------eenNKTSTLPkkVHKIIE---VSGRKPEQVDCNFDLLYVNDDQ---EFCIEEIL 349  Naumovozyma c...
CCK68931      307 KMAIFHD----------------------SLGRSDP--VYTTLP---SCDDKSEKIDCNFALVYDQDE----EYSIEMIL 355  Kazachstania ...
Q6FSY2        304 KMILFQD----------------------NLGRSEP--VYKLIK---NNSGKLEKIDYNTNLLIYEGR----EICLEEIL 352  [Candida] gla...
CCK70631      226 KLPIFKDaeddephmlrvntnleplssikEGERENP--IYKIVK---LPNRKPERIDCNFNLLYTQNGE---EFSIEQIL 297  Kazachstania ...
XP_003013793  330 KMTVFKDet-------------------iNVSRNNK----ERVD---PRTGKIERVVVNLEAIYPDSHNpavEMSLDELR 383  Trichophyton ...
CAZ83185      318 KMMIFRDes-------------------sLPKQNVPpvQQNVLPtylPSNKRPERVAVNLELIYADEENpteELSFDELR 378  Perigord truffle
CCE41201      303 KLQIYCDdssntaiiqvedtgthrsiqscKDSRH----VYTLIE---APGKRPEKVMLNMELLYSNVDS---EISSVELL 372  Candida parap...
4BL0_E         57 A---MIKGL------YKVQRR 68   baker's yeast
Q6FQ60        304 AkssISRDI------LRKKQD 318  [Candida] glabrata
CCF60444      308 A---LSRNV------YHKNNY 319  Kazachstania africana CBS 2517
XP_003673647  350 A---LSRGL------YYKTRE 361  Naumovozyma castellii CBS 4309
CCK68931      356 A---VSRGLlaagycHKRRRL 373  Kazachstania naganishii CBS 8797
Q6FSY2        353 T---MMKSN--------TQNN 362  [Candida] glabrata
CCK70631      298 A---KKRDL------YDKRST 309  Kazachstania naganishii CBS 8797
XP_003013793  384 A---IRRGW------MSKDWS 395  Trichophyton benhamiae CBS 112371
CAZ83185      379 A---IKRGQ------YGIDWN 390  Perigord truffle
CCE41201      373 A---MQRRT------LQTRES 384  Candida parapsilosis
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