Conserved Protein Domain Family
RIX1

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pfam08167: RIX1 
rRNA processing/ribosome biogenesis
Rix1 is a nucleoplasmic particle involved in rRNA processing/ribosome assembly. It associates with two other proteins, Ipi1 and Ipi3, to form the RIX1 complex that allows Rea1 - the AAA ATPase - to associate with the 60S ribosomal subunit. More than 170 assembly factors are involved in the construction and maturation of yeast ribosomes, and after these factors have completed their function they need to be released from the pre-ribosomes. Rea1 induces the release of the assembly protein complex in a mechanical fashion. This family is usually associated with NUC202, pfam08166.
Statistics
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PSSM-Id: 400472
View PSSM: pfam08167
Aligned: 90 rows
Threshold Bit Score: 84.1705
Threshold Setting Gi: 301121945
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EKV10786        5 TLRAVTHRLITT---------PVEQLPSIASFLATSLNDCAELLSTPQTqksgksdsdnavqIHKLKTRLASLLQDRSVE 75   Penicillium d...
XP_004920840   15 ITGLLERDLSEG------------ELAETIRGLREHGALRGEGLPAAMSg---------------LLSSCNSRLISA--G 65   tropical claw...
XP_006627570   19 LLSALQEEQPGH-------------LPGLLASYREHGGV-SAQSAGVVGn---------------LIGFSNARLSST--K 67   spotted gar
XP_002908699   21 LALAFPSELEND-------------HAALESFLTQQAALREALERHNVFglvt-----dgkaLTKWQTRLLQLVEGS-SA 81   Phytophthora ...
XP_004952309   18 KPRLLRAVVAERlpqpggaelPPVELASVLDAVRTHGLLTEALPDRApadpkla--eawraaVDSWVERVVALVVSDSAY 95   foxtail millet
XP_015693103   18 LRLXGGGGGGRRpkpg--galPPAELATVLDAVRTHGLLTERLPGthdpkla----eawraaVDAWVERIGELVQSDMPC 91   malo sina
XP_010234184   17 KPRLLRAVVSERlpka-gstvPPAELFSILEAVRTHGLLTESHLDaldhkla----eawraaVDSWVDRVVELMASDSPY 91   stiff brome
ERN20386       16 RPRLLRSLMADRvpdekrplsSPLELSNVVSCIKLHKLLSETYPVkvdksnf----ndwksaVDSWIERLLSLASSEMPD 91   Amborella tri...
XP_009109604   16 KPKILRNLLSEYvpnekqplvDFQSLSKVVSTISTHKLLSESPSSsadqkkiq--akpsksaVDEWVERLLALVSSDMPD 93   field mustard
XP_004249969   16 KPRLLRSLLKEYvpdlkhqfrNPSVLSYVVSAIKTHQLLSESAPPesdekli----enwtaaVDSWINRVVGLASSDTPD 91   tomato
EKV10786       76 GRWTAVVLVKATVEAGQw-EILRGYEPIVRSLISILAKPd--------pISTRKMCIVTLTRIFH-LTYQYPTLVREITT 145  Penicillium d...
XP_004920840   66 TRVEGLSLLALAVEESPtgVFEQHCVSWLRSILQIIQSQd--------pPRVVSLAVFVLRSLLA-HSSALPELSREIST 136  tropical claw...
XP_006627570   68 TRFQGLCLLSVLVRDSSsdVFQQHCLSWLRAVQQVIQSQa--------pLPSVQLAVTILQDLLQ-YSSQLPELSREIGL 138  spotted gar
XP_002908699   82 ARRVGWELLQTTVRQSPleRLEALAVKLLERIVKVLKQQqssktqdddaEYATAAACGVAQALLLhVDKFNPDTRREVLE 161  Phytophthora ...
XP_004952309   96 SCWLGTCFLGVTFQECSneRFAESYSNWYEKILPNLQQEps------tlQLVTVISCTSMSDLFV-RLAKFSNLKKEASS 168  foxtail millet
XP_015693103   92 SRWLGICFLGLTFQECSneRFAESYSNWFEKILSNLQGPss-------eQLVIIVSCTSMSDLFV-RMARCLNLKKEASS 163  malo sina
XP_010234184   92 SCWLGTCFLGVTFQECSnmRFLQSYSDWFEKILRNLQEQss-------lELVTAVSCTSMSDLFV-RLANFLNLKKEASS 163  stiff brome
ERN20386       92 KCWAGVCLLGLTIQECSldRFVASYSNWFQRLLVHLKPAsg-------sHFIKVTACASLLDLFT-RLGGIPNVKKEGTS 163  Amborella tri...
XP_009109604   94 KCWGGVVLIGVTCRECCsdRFFSSYSVWFNSLLSHIKNPes-------sRIVLVASCTSVSDLLT-RLSRFTNTKKEAVS 165  field mustard
XP_004249969   92 KCWAGICLLGVTSQECSreRFIASYAAWFNKLLVHLQSPad-------sQFVKVATCASLSDLFT-RLSGLPNAKKDGIA 163  tomato
EKV10786      146 PQLPGFITAALNLVSTItktpsgsvrkpkpntpfMEIVLHALLELIPRHTTIFRPFGAQLRTLLAEVIGSSSPAY 220  Penicillium digita...
XP_004920840  137 NHIPGLLTSLLGLRRQC-----------------LVPALEGIRSCFISYPRACGSLRGKLTAFLLSLIDAENQQI 194  tropical clawed frog
XP_006627570  139 NSIPGILTSLLGLKQEC-----------------HLGAMEGMTACMTYYPRACGSLREKLGAYFLSKMDSDNPKI 196  spotted gar
XP_002908699  162 L-LGKLLQPLVALLRQTsns------------plVIAQLDLVATLLRSSPNSLRSYAIKIESACVDLLFTCERDN 223  Phytophthora infes...
XP_004952309  169 F-AGRIIESVLRLLNENgl--------------vADEAIDLLCTVIKLYPSSVNRHYNKVESTIAAKVMSTEVNV 228  foxtail millet
XP_015693103  164 F-AGRVVEPVLLLLNGNgp--------------vANEAVDLLRTVIKLYPSSVNRHYNKVESSIATNVMSSEVNV 223  malo sina
XP_010234184  164 F-AGRVVELLLLLLNENgp--------------vVDEAVDLLTTVIKLYPSSVNRHYNRVESAIAAKIMSTEVNV 223  stiff brome
ERN20386      164 L-AGKLIQPILQLLSEDcse------------tvCEGVVDLLCTLITFFPSSIHHHYDNVEAAIASKIISGTCST 225  Amborella trichopoda
XP_009109604  166 H-ASKVVLPIIKLLEEEsse------------alWESIVHLLSTIVILFPAAFHSSYDKVESVIASKIFSTKTSS 227  field mustard
XP_004249969  164 L-STKLIQPLLKQLNEDkfd------------asWEEAIFLLCSILDIFPSSIQRHYDGVEEAIVSRLLSGKCNP 225  tomato
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