Conserved Protein Domain Family
AdoMetDC_leader

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pfam08132: AdoMetDC_leader 
S-adenosyl-l-methionine decarboxylase leader peptide
This family consists of the S-adenosyl-l-methionine decarboxylase (AdoMetDC) leader peptides. AdoMetDC is a key regulatory enzymes in the biosynthesis of polyamines. All expressed plant AdoMetDC mRNA 5' leader sequences contain a highly conserved pair of overlapping upstream ORFs (uORFs) that overlap by one base. Sequences of the small uORFs are highly conserved between monocot, dicot and gymnosperm AdoMetDC mRNA species, suggesting a translational regulatory mechanism.
Statistics
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PSSM-Id: 489407
Aligned: 2 rows
Threshold Bit Score: 82.0748
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ERN07116      1 MESKGGLKKKSSSNSRFYEAPLGYSIEDVRPHGGIEKFRTAAYSNCVRKPS 51 
1_pfamImport  1 MESKGGKKKCSSSSSLQHEAPLGYTVEDIRPNGGIKKFQSAAYSNCVRKPS 51 
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