6GCS,7ZM8,5GUP


Conserved Protein Domain Family
NDUF_B12

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pfam08122: NDUF_B12 (This model is not part of the current CDD release)
NADH-ubiquinone oxidoreductase B12 subunit family
This family consists of the NADH-ubiquinone oxidoreductase B12 subunit proteins. NADH is the central source of electrons in the mitochondrial and bacterial respiration. NADH-ubiquinone oxidoreductase is involved in the transfer of electrons from NADH to the electron transport chain. This oxidation of NADH is coupled to proton transfer across the membrane, generating a proton motive force that is utilized for the synthesis of ATP. The function of this subunit is unclear.
Statistics
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PSSM-Id: 518077
Aligned: 79 rows
Threshold Bit Score: 47.1754
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6GCS_c         6 KDPWARREAWRYQTNFTRANRFKGAA-PGFGIAVVAFGAYLAAEKFLFeKKDDHHH 60  Yarrowia lipolytica
NP_001232802  40 RDPWARNEVWRYQGSFARPITVIEIFtRGLKWGAAAFVIALGIEYSLFpPKKNGGH 95 
XP_028925633  40 RDPWGRNEAWRYSGQYAKSPTFLGAItRGFKWGFAAFVVAVGVEYYLTaGEKTESH 95 
XP_003765926  42 RDPWARNEAWRYMGRFGKTPTLWTALtRGFKWGFGAFLLAVGVEYYLTaPKNEEEH 97 
XP_006153084  44 RDPWARNEAWRYMGGFANNVSFIGALlKGFKWGFAAFVVAVGTEYFLEsSNKDKKH 99 
XP_003507076  43 KDPWARNEAWRYMGGFAENITFMHVLlKGFKWGSAAFVAAIGIEYFLTsQNDKKNH 98 
Q9CQZ6        48 RDPWARNEAWRYMGGFAGNITFPSVIlKGFKWGFAAFVVALGAEYFLDsQNGDKKH 103 house mouse
5GUP_Z        42 RDPWGRNEAWRYSGGFANNVSFVGALlKGFKWGFAAFVVAVGAEYYLEsQNKDKKH 97  pig
Q0MQD0        38 RDPWGRNEAWRYMGGFTKSVSFFDVFfKGFKWGFAAFVVAVGAEYYLKsLNKDKKH 93  Bornean orangutan
XP_038953324  48 RDPRTYNEAWRYMGDFASNITSMSVIvKGFKLGFAAFVVALGAEYFLAsQNEDKNP 103 Norway rat
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