pfam08063: Zn_ribbon_PADR1 (This model is not part of the current CDD release)
PADR1 domain, zinc ribbon fold
This is the zinc ribbon fold of the PADR1 domain found in poly(ADP-ribose)-polymerases, referred to as the third zinc-binding domain of these proteins. The PADR1 domain is involved in protein-protein interactions that orchestrate PARP-1 activation and are critical to the DNA-dependent stimulation of PARP-1. PADR1 consists of an N-terminal helical region, the central zinc ribbon fold and a C-terminal tail.
Jiyao W et al.(2023). "The conserved domain database in 2023.",