8FKW


Conserved Protein Domain Family
NOP2_rpt

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pfam08062: NOP2_rpt (This model is not part of the current CDD release)
NOP2 repeat
This entry represents a characteristic repeat found in 28S rRNA (cytosine-C(5))-methyltransferase (NOP2, also known as proliferating cell nuclear antigen p120, which it is found in three copies. NOP2 is involved in ribosomal large subunit assembly. It is also a SAM-dependent methyltransferase that specifically methylates the C5 position of cytosine 4447 in 28S rRNA.
Statistics
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PSSM-Id: 518049
Aligned: 6 rows
Threshold Bit Score: 23.5926
Created: 14-Feb-2025
Updated: 25-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
8FKW_SY      749 LGRAKGVEK---QQLPEQPFEKA 768 human
Q922K7       663 AGNADVNSKrkrSEKLKQRGPKW 685 house mouse
Q922K7       609 TKKARGAVKa-kQQLLRQPHSKK 630 house mouse
1_pfamImport   1 LGKAKGTEKv-kQQLPEQPF-KK 21 
XP_003820354 619 AKKAKGAAKt-kQQLQKQQHPKK 640
NP_006161    679 AGKAEGIREpkvTGKLKQRSPKL 701 human
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