Conserved Protein Domain Family
NPCC

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pfam08058: NPCC 
Nuclear pore complex component
Proteins containing this domain are components of the nuclear pore complex. One member of this family is Nucleoporin POM34, which is thought to have a role in anchoring peripheral Nups into the pore and mediating pore formation.
Statistics
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PSSM-Id: 400412
View PSSM: pfam08058
Aligned: 23 rows
Threshold Bit Score: 116.999
Threshold Setting Gi: 156117568
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_710621    218 GSWENPIVKEAISRQ-INL--EYQMKSLIRNIIYLM-----------------IFILFKSSISKLLvlllnarSISS--- 274 Candida albican...
CCK73026      80 GSFENPVLDKVISRT-INK--ESEFQVVVTNVLIFF-----------------LWNLLYKSTQLLLehsaygrKLSKqcm 139 Kazachstania na...
XP_003676217 139 GNFESPVLVNLLQRS-VSK--EQETQTIIANLVFFF-----------------VWNLIVKFVGLYFkhttngrMVLLkin 198 Naumovozyma cas...
CCF60168     138 GNFENPILGKLVKRS-ISK--EFEIQKIIINVISIA-----------------LFNLLSKFSILFInhskvgrRFHLfys 197 Kazachstania af...
Q6FW38        87 GFFENPVLEKLAERS-VNK--SLEVQKIINNVLLYL-----------------LWNLITKFILLYLdhtssgqKVRKnwl 146 [Candida] glabrata
Q75FA1       129 GNYENPALAAFTRRV-VNK--EQEIKRIIANVWTLL-----------------IWNLVYKFLGLFLqssrtgrFIYQsls 188 Eremothecium go...
Q12445        40 GNFESPVLKELSRRT-VNK--EMETQRIMTNVIAFA-----------------FWNLLVKFIKFFWnnthvgrQFCNrls 99  Saccharomyces c...
EJT44035      40 GNFESPVLKELSRRT-VNK--ELETQRIMTSAIAFA-----------------LWNLLMKFIRFFRdnthvgtQFCNrls 99  Saccharomyces k...
EDU44108      30 GSWKHPQFEEIARRQyATTfdERNIRAIILNTGILFlsvwgnamtekvklleyAATPINALVKAVP-------------- 95  Pyrenophora tri...
EOA84322      30 GAWRHPQFDEIARRQyATVfdERNVRAIVLNSGLLFlsiygrgvtekvklleyAATPIHALARAVP-------------- 95  Exserohilum tur...
XP_710621    275 -------------------TKESDSqlynyshnnhmiipqssssssisvsntstiaFYFVLITKLIIGYFIISIIIAGFK 335 Candida albican...
CCK73026     140 qtlwslqrahprwgplwqlFQDASV-------------------------------VKADYLNHLVGIVLGFNIVTALFK 188 Kazachstania na...
XP_003676217 199 kklw--------slgwltkLFNNSYfrsm------------------------flwITWDHVEHLVHIIVALNVIISIWK 246 Naumovozyma cas...
CCF60168     198 nviq--------sclnnfwNVDGMKkiyffwikvny----------nyfnnklsfhLTAEHLIHGFYLLVAYNIILSMWK 259 Kazachstania af...
Q6FW38       147 qtdq--------ilallhmPNNKAAenai------------------------dllFSVSSFNKAFRGLVLYNVLMSIFA 194 [Candida] glabrata
Q75FA1       189 hffy--------anvvfklNPHARLdsgw------------------------frfWTLENISHLIHMLLLINIALSLYM 236 Eremothecium go...
Q12445       100 rihl--------ymltfhtLKKANIiyht-----------------------tfswLNAELLDYLFHLLISLNILFSLWK 148 Saccharomyces c...
EJT44035     100 rihl--------ylltfhaVKQVNIiyys-----------------------tfswLTAELVDYLFQLAISLNILFSLWK 148 Saccharomyces k...
EDU44108      96 ---------------------------------------------------------YSHWGVLLIRFLFVANIVIAFLP 118 Pyrenophora tri...
EOA84322      96 ---------------------------------------------------------FSAWAIVLVRLVFAANIVIAFLP 118 Exserohilum tur...
XP_710621    336 LLKGq--DQCYDLPLTIHQRKLLGLKVNdvpe-----dyiIDEKAEMILKQRRY 382 Candida albicans SC5314
CCK73026     189 LRSR---INTRDLELTQRQRELLGLDPRnh---------pQGDTKGGHITKPHV 230 Kazachstania naganishii CBS 8797
XP_003676217 247 LFTK---VKTNDLNLTPKQKTLLGIDDEmskmnlptrlvgiSSDNKRRIEKPHv 297 Naumovozyma castellii CBS 4309
CCF60168     260 LFMT---INMNDINLNEKQRTLLGLNAAs----------iTQQNHATPIMKPhi 300 Kazachstania africana CBS 2517
Q6FW38       195 LVGK---VKISDLKLNQRQKNLLGFIGQ-------------GETSNLRRIEPSN 232 [Candida] glabrata
Q75FA1       237 LLVKaqhITVGDLGLNERQKELLGVSASs----------dTRNSIIEDVTNPRP 280 Eremothecium gossypii
Q12445       149 LLST---VKVSDLNLTDRQKKLLGVDMQs-----------SVDTGLQP-QHPHY 187 Saccharomyces cerevisiae S288C
EJT44035     149 LLST---VNVSDLNLTRKQRRLLGVDIQp-----------LVNDGLQP-QQPHY 187 Saccharomyces kudriavzevii IFO 1802
EDU44108     119 LVRRyypDDMADIALTPSQRAAMGLKADvnap----ptpgSVYASPNYVTPPRY 168 Pyrenophora tritici-repentis Pt-1C-BFP
EOA84322     119 LVRRyypDDIADIPLTPSQRASMGLKTDvhap----ptpgSAYASPNYVTPPRY 168 Exserohilum turcica Et28A
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