5M6S


Conserved Protein Domain Family
Tna_leader

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pfam08053: Tna_leader 
Tryptophanase operon leader peptide
This family consists of the tryptophanase (tna) operon leader peptide. Tna catalyzes the degradation of L-tryptophan to indole, pyruvate and ammonia, enabling the bacteria to utilize tryptophan as a source of carbon, nitrogen and energy. The tna operon of E. coli contains two major structural genes, tnaA and tnaB. Preceding tnaA in the tna operon is a 319 -nucleotide transcribed regulatory region that contains the coding region for a 24-residue leader peptide, TnaC. The RNA sequence in the vicinity of the tnaC stop codon is rich in Cytidylate residues which is required for efficient Rho -dependent termination in the leader region of the tna operon.
Statistics
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PSSM-Id: 369671
View PSSM: pfam08053
Aligned: 3 rows
Threshold Bit Score: 36.9817
Threshold Setting Gi: 83287857
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5M6S_A 147 NILHISVTSKWFNIDNKIVDHRP 169
P0AD89   2 NILHICVTSKWFNIDNKIVDHRP 24  Escherichia coli K-12
P0AD89   2 NILHICVTSKWFNIDNKIVDHRP 24  Escherichia coli K-12
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