4UD8,5D79


Conserved Protein Domain Family
BBE

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pfam08031: BBE 
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Berberine and berberine like
This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine.
Statistics
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PSSM-Id: 369658
View PSSM: pfam08031
Aligned: 44 rows
Threshold Bit Score: 54.8707
Threshold Setting Gi: 81709687
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4UD8_B   475 AYVNYRDLDLGtnegetdarEWGAKYYK-GN-FERLVKIKGEFDPDNFFRHEQSVP 528 thale cress
Q7V3Z6   524 SYVNEGNFFEP---------NWKQEFWG-PN-YERLLGIKRRYDPTNLFRVHHGVG 568 Prochlorococcus marinus str. MIT 9313
M1W0X9   412 SYRNLGDPQEK---------EFQARYWGaDN-YARLAATKAAWDPSHLFMTSLGVg 457 Claviceps purpurea 20.1
Q7SB35   597 GYLNEGDVMEP---------EFGEAYFG-SN-YERLSQIKKAVDPTGLLWAPTAVG 641 Neurospora crassa
EED46866 503 AYLNEADFRQP---------NFQKYFYG-DN-YATLRKIKAKYDPDNLFYATTAVg 547 Aspergillus flavus NRRL3357
EAA32028 507 AYMNEGNFQQP---------DFQHQFFG-SN-YNNLLCIKKKYDPTNLFYATAAvg 551 Neurospora crassa OR74A
Q7RV07   419 TYAGYVDPELK---------DAPQQYWG-SN-YEELRRVKKVWDPKEVFWNPQSVR 463 Neurospora crassa
Q7S1P7   453 mYINYADPTMKr-------aEAVGNYYR-SS-LSRLQKVKAQYDPNEVFYYPQSVE 499 Neurospora crassa
Q8Y3D0   458 CYINYPDVDMLay------pFWPQLYYGdGDlYAFLQRVKRRYDPNNIFHHAMSVR 507 Ralstonia solanacearum
Q9EX55   495 CYINYADADLAdpalnrsgiPWHELYFK-GN-YPRLQRVKATWDPRNVFSHRLGIR 548 Streptomyces coelicolor
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