2ISM


Conserved Protein Domain Family
GSDH

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pfam07995: GSDH 
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Glucose / Sorbosone dehydrogenase
Members of this family are glucose/sorbosone dehydrogenases that possess a beta-propeller fold.
Statistics
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PSSM-Id: 400382
View PSSM: pfam07995
Aligned: 90 rows
Threshold Bit Score: 265.567
Threshold Setting Gi: 123380600
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2ISM_A         30 LEVP---WAL------AFLPD-G-GM-LIAER-PGRIRLFR---EGRL--STYAEL----------SV-YHRGESGLLGL 80  Thermus thermo...
Q1H3Y7         78 DQYPtgpFEMlgnkhfLFITKcG-EVyFTRINeSGEIEITKn--ADSLtkPGLDEReeskgddydgLV-YCKELAGVKDS 153 Methylobacillu...
Q3IH25         69 LQSP---WSM------VELAN-G-TW-LITER-DGHVVIIKnnaQSRVk-LNLEGL-------------YLAGQGGLLDI 121 Pseudoalteromo...
Q2LUD0         82 LNVP---WSL------VFLPD-K-RA-LVSER-SGKIRLII---NGKLesHPYATV----------DA-VRIGEAGLMGL 134 Syntrophus aci...
Q1CXL1         59 LETP---WGI------AWLP--GgDA-LVTER-PGRIRLLK---DGVLqpRPVATVp----------V-ADAAEGGLLGI 111 Myxococcus xan...
jgi:Noca_2041  50 LDHP---WDV------RPIGD-G-RL-IFTQRdRATVSIWD---GSRT--RLVQGFp--------sDSvWVSGETGLMGL 104 Nocardioides s...
Q0S4Q3         65 LDHP---WDA------VQAPD-G-AV-LTGQR-SGGFFVRRa--NGST--GPVTADl--------sDL-YAQSETGLMGI 118 Rhodococcus jo...
jgi:Nmar_1561  49 LEKP---RSI------AVS-D-N-RI-FVTEK-DGSIVVIE---NDIQleSPLATF----------RS-ANVFDGGLLGI 100 Nitrosopumilus...
ABK78628       76 LDEP---RHL------AFYGD---RV-FLTEK-AGRVRVVQ---DDVLleEPLAVL----------RV-ADELDSGLLGI 127 Cenarchaeum sy...
jgi:Nmar_0371  47 LKIP---WGI------DFAQD-G-RI-FFTER-PGTVNVIE---DGQV--SQIMSR----------GV--GGGEGGMLGI 96  Nitrosopumilus...
2ISM_A         81 ALHPRFPQEPYVYAYRTVA---EGGLRN-QVVRLRHLGE--RGVLDRVVLDGIPA-RPH--GLHSGGR-IAFGPDG-MLY 149 Thermus thermo...
Q1H3Y7        154 LLVGN-----TLYVVYTTWdheANGARL-AVSAFELDQEqsELTFSKDIFLTYPAvKEPflGHQVGGK-LVLGADDdTMF 226 Methylobacillu...
Q3IH25        122 VLSPDYSNSKEVIFTYAqg--dANANWL-VVAKATFNGT--RFSKPQIIYKVATN-KNT--PQHYAGRaLVLP-DN-TLL 191 Pseudoalteromo...
Q2LUD0        135 AMHPRFPAEPYIYAMYTEQk--KGALRN-RVVRFRDhg--rTGSFDRVILDDIPG---G--RFHDGGR-IAFGPDG-MLY 202 Syntrophus aci...
Q1CXL1        112 AAHPNFANNRQFYIYVTTDa--GGTEEN-RIERWTLSEDhtTATHERVIFGGIAS---A--KYHDGGR-LRFGSDG-MLY 181 Myxococcus xan...
jgi:Noca_2041 105 EVDPSFASNRTFYTCQGGFt-aGGGHDV-RIIRWTLRDDlvSISGSKRLLGGLPA--TS--GRHGGCRlLAVGK---RLY 175 Nocardioides s...
Q0S4Q3        119 ALASNFANTRTLYTCQGFQ---GGGVTDiRIQSWTVDAGwtTLTRGSAILTGIPV--NE--GRHGGCR-ILTAADG-TLF 189 Rhodococcus jo...
jgi:Nmar_1561 101 DLHPNFAENHYLYVFLTYEe--DEALWN-KILRITESEN--KLQDAETIFDKIPG---S--SFTNGGF-IKFGPDG-KLY 168 Nitrosopumilus...
ABK78628      128 AVHPDFGENHKLYVYHSYIe--DGAAWN-RILQITERDN--KLEDAETVLDKIPG---S--RFSNGGV-IKFGPDG-KLY 195 Cenarchaeum sy...
jgi:Nmar_0371  97 ALDPEFEKNHYVYVYYTYNe--LLGIKN-RLVQYVESDN--KLNHEKILLEDIPG---A--PYHDGGR-IKFGPDE-MLY 164 Nitrosopumilus...
2ISM_A        150 VTTGEVYE-RELAQDLASLGGKILRLT-PEGEPAPGNPFLgr-rgARP-EVYSLGHRNPQ-GLAWHPKtGELFSSEHGPS 224 Thermus thermo...
Q1H3Y7        227 LSVGDFSK-PDGVQDPSTALGKMIKINlKDASA----------------EIYASGLRSPSgGLYFDRDsNELWETEHGPK 289 Methylobacillu...
Q3IH25        192 VSTGDGFDfREQAQVITSQLGKILRIN-LNGSIPTDNPFInh-tnPNAhAVYSLGHRNPQ-GLVYDYDtQQIISHEHGPA 268 Pseudoalteromo...
Q2LUD0        203 VTTGENFN-ADLAQDRSSLAGKILRIS-PDGEIPADNPF------KDS-PVYSYGHRNPQ-GLAWQPEtGRLFESEHGPS 272 Syntrophus aci...
Q1CXL1        182 AGTGDARD-PDRSQNANDPAGKLLRLT-PEGAVPQDNPI------PGS-PAFLTGIRNLQ-AFDWR-DaSTLYIADHGPS 250 Myxococcus xan...
jgi:Noca_2041 176 AGTGDAAT-GSTPENKKSLGGKTLCLLaATGKPCGSNPFAgsknhNKR-YVHTYGHRNVQ-GLDRRRD-GTLWSVEQGSY 251 Nocardioides s...
Q0S4Q3        190 IGTGDTAQ-PTVSQDPNSLGGKTLHIN-TDGTPAAGNPD------PAS-PVYTLGHRNAQ-GLAQQPGtGRIYAVDQGTT 259 Rhodococcus jo...
jgi:Nmar_1561 169 VGTGATSDsSHLPQDLDSLSGKILRIN-DDGSIPDDNPF------SNS-PVYSLGHRNPQ-GMTWDNN-GNLYVSEFGPE 238 Nitrosopumilus...
ABK78628      196 VGTGSVSDtLHLSQEMDSLGGKILRIN-DDGSIPSDNPF------EGS-PVYSLGHRDPQ-GMAWSSD-GTMYASDLGPS 265 Cenarchaeum sy...
jgi:Nmar_0371 165 VTTGDAVE-PELSQNLNSVAGKILRIK-SDGTIPEDNPF------GSA--IYSIGHRNPQ-GIAWD-KsGNLIATEHGPS 232 Nitrosopumilus...
2ISM_A        225 GEqgy-ghDEVNLIVPGGNYGWPRVV----------GR--------GNDPR-YRDPLY-FWPQG---FPPGNLAFF---- 276 Thermus thermo...
Q1H3Y7        290 GG------DEINLIKQGRNYGWPLVSygtlyeregmGNyyg--nkyNSHED-FEKPAF-VFNPS---IGVGAIAKYpktg 356 Methylobacillu...
Q3IH25        269 GG------DELNYLTAGNNYGWPVITngd----dysQAris---pfRDYPG-MAKPSL-DWTPS---IAPSGMAYYgskh 330 Pseudoalteromo...
Q2LUD0        273 GEfahfghDEINRIVKGGNYGWPLVI----------GA--------PEIQP-YIDPLI-VWKEA---TPPGGIAFYngtf 329 Syntrophus aci...
Q1CXL1        251 GEtlrrghDEVSVARRGDNLGWPGIY----------SC--------ETREG-QITPSI-TYKDA---MPPGGAAIYtgta 307 Myxococcus xan...
jgi:Noca_2041 252 RD------DEVNRLRKGGDYGWNPVP----------GYdesvpmtdQSLPGrQRAA---VWRSGdptLATSGGGFVygkr 312 Nocardioides s...
Q0S4Q3        260 RD------DEVNLLVAGGNYGYKPDRipg----iydESvp------mTDPSrVPGAVAaAWSSGsttLATGSAAFVtgpg 323 Rhodococcus jo...
jgi:Nmar_1561 239 KN------DEINIILAGKNYGWPEQEc-------------------SGNES-FENAVL-CYDPS---IEPGGILYYtgdk 288 Nitrosopumilus...
ABK78628      266 KN------DEINVIIPGGNYGWPDHE--------------------CSGGG-YEDSIL-CFDPA---IEPGGLVVYsgeq 314 Cenarchaeum sy...
jgi:Nmar_0371 233 GWrgv-ahDEINWIVSGANYGWPDVI----------GD--------ETLEG-ATNPILhSGDDT---WAPSGSTFYygdd 289 Nitrosopumilus...
2ISM_A        277 ------RGDLYVAGLRGQALLRLVL-EgErgrwrVLRVETa------lSGFG-RLREVQVGPDGALYVTTSnrDG---R 338 Thermus thermop...
Q1H3Y7        357 k-neywEGGFFVAGMAANSLLYMR--KeGe---rLVYAEPv--------lHDyRIRALKIDKNGRFFIKTDn-DQflwm 420 Methylobacillus...
Q3IH25        331 aafpslQNHVLITTLVDKKLYAVNL-AnG-----EFTQSHi------fPEATgRLRDVFVTTEGNVAILTDgeDA---K 394 Pseudoalteromon...
Q2LUD0        330 --lphlKGDLFVATLKSRALIRVRF-DgDt---kISRIERwfstdfkkGKYG-RLRDVVTGPDGAIYFTSSnrDG---R 398 Syntrophus acid...
Q1CXL1        308 --ipewKGSLLIGTLGSRHLQRVEF-ApDss--rVTRHEVyl-----rNTYG-RLREVIMGPDGHLYVTTSncDG---R 372 Myxococcus xant...
jgi:Noca_2041 313 --wgalDGSFAVAALKAERVLFLQL-SaSgr-lqRVRVPAal------rQHG-RIRTVVDGPGSVAYVTTDngNG---N 377 Nocardioides sp...
Q0S4Q3        324 --wgpwDGALVMGGLKTKQLIFLRLaAdGq---sVTAQTFgl-----qNQYG-RLRSVTPTADGSLLVTTD--NGstdQ 389 Rhodococcus jos...
jgi:Nmar_1561 289 ---fdfEFPFIMASMRASNVYQVDF-DeG-----LSSQKSi------lSGIG-RVRDVVQGPDGYLYVITSntDG---K 348 Nitrosopumilus ...
ABK78628      315 ---lefGGSLIMTSLRVGSLYGFDPtDgG-----LEDRQSi------lAGLG-RIRDVDEGPDGYLYALTSntDG---R 375 Cenarchaeum sym...
jgi:Nmar_0371 290 --mpmfDGKYFVAALKGQHIHVIEF-DeSy---nVLFHGElf-----sGEFG-RIRDVANGPDG-LYFMTSnqDG---R 352 Nitrosopumilus ...
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