2DKH


Conserved Protein Domain Family
Phe_hydrox_dim

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pfam07976: Phe_hydrox_dim 
Phenol hydroxylase, C-terminal dimerization domain
Phenol hydroxylase acts a homodimer, to hydroxylates phenol to catechol or similar product. The enzyme is comprised of three domains. The first two domains from the active site. The third domain, this domain, is involved in forming the dimerization interface. The domain adopts a thioredoxin-like fold.
Statistics
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PSSM-Id: 400366
View PSSM: pfam07976
Aligned: 250 rows
Threshold Bit Score: 98.3708
Threshold Setting Gi: 134082766
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2DKH_A       441 FTAGVGTHYAPSLLtgqakhqALASG--------------FTVGMRFHSAPVVRVCDAKPVQLGHCGKADGRWRLYAFAa 506
XP_002794301 446 LTSGYGVAYQPNIF-------NWGPDhpakspllnsvgvkLVSGRPFPPCTVTRLSDAYKVALEQEVPINGSFRIHIFA- 517 Paracoccidioide...
XP_002487142 409 FTSGYGVAYDPNVI-------NWSPShpaqshlfgidgvkLVPGRAFTPTTVTRLSDANMIHLEQEVPANGSFRVFVFA- 480 Talaromyces sti...
GAD91775     410 FTSGYGVAYNANIF-------NWSPShpaksplfnvpgvkLRVGRAFTPSKVTRLSDANFVNLEQEVPANGAFRIFVFA- 481 Byssochlamys sp...
Q4WZW6       411 FTSGYGVAYKPNVF-------NWSPShpaqsplfdipgikLTPGRAFTPTTVTRLADANFVHLEQEIPANGAFRIFIFA- 482 Aspergillus fum...
CBF79728     413 FTSGYGVAYLPNIF-------NWDPShpaksplfdvpginLVTGKAFTPSTVTRLADSNFVHLEQEIPANGAFRIFIFA- 484 Aspergillus nid...
EHA21143     412 FTSGYGVAYKPNVF-------TWDAThpaqsplfdvpgvrLTPGRAFTPTTVTRLADSNHVHLEQEIPANGAFRIFIFA- 483 Aspergillus nig...
EPS32694     408 FTSGYGVAYKPNVF-------NWDAShpaksslfdisgvrLTPGRAFTPSMVTRLADANFVELEQEVPVNGSFRIYVFA- 479 Penicillium oxa...
XP_002844109 399 FTSGYGIVYPPNVF-------NWDPNhraksplflpggngLIPGRVFPIATVTRVSDAYPVHLEQEIPMNGSFRILIFA- 470 Microsporum can...
EGE01310     399 FTSGYGIIYPPNAF-------NWHPNhraksplfiseakgLKPGRCFPPATVTRLVDSNPVHLEQEIPLNGSFRILIFA- 470 Trichophyton eq...
2DKH_A       507 qNDlaqpE----SGLLALCRFLEgdaaSPLRRFTPAGQd----------iDSIFDLRAVFPQAYTEVALETLPALLLppk 572
XP_002794301 518 -GN----PaktrEAVNDFASHLVkk-lSFYSSYQQRDIdtvsyferhnphSRFFTLTVIFSGQKCAKRIDQLPKVLR--- 588 Paracoccidioide...
XP_002487142 481 -GT----PqkskKALEDFASYIEke-kSFLSVYRRPDIanvsyferhnphSKLFTLNFIFASEKNGVDMQSLPQIVK--- 551 Talaromyces sti...
GAD91775     482 -GV----PaktkQALTDFAASLEke-rSFLSVYRRPDIssvshferhnphSKLFTISVVYASDKNGINLPELPNLLK--- 552 Byssochlamys sp...
Q4WZW6       483 -GK----QantkKAITDFGANLEke-rSFLSSYRRIDeisffe--rhlphSKLFSICLIYAAQKNEVDVEAIPQILR--- 551 Aspergillus fum...
CBF79728     485 -GR----QsrskKAIADFAANLEke-rSFLSAYRRSDIgeisfferhnphSKLFTLCLIYAEKKNDIDMDSIPQILR--- 555 Aspergillus nid...
EHA21143     484 -GK----QdktsKAITDLAANLEke-rSFLSVYRRADIadvsffenhlphSKLFSICLVYAGEKNQIDVDSIPKILR--- 554 Aspergillus nig...
EPS32694     480 -GN----QaktsKAIADFAANLEke-rSFLSAYRRPDIasvsfferhnphSKLFTISVIYAANKNEVDVDSIPQILR--- 550 Penicillium oxa...
XP_002844109 471 -GS----LdksrAALADFCQYLEkp-sSFYSSFATPKLlpdrdfekhnphSRFFTLAVIFIAEKDDVDISALPSPLR--- 541 Microsporum can...
EGE01310     471 -GS----LdrsrTALTDFCQHMEkp-sSVYSLFATPEHspdpyfekhnphSKFFTLAAIFMEEKDNVDISTLPRLLK--- 541 Trichophyton eq...
2DKH_A       573 gqlgmiDY-EKVFSPDLK----NaG-Qd-IFELRGID-RQqG 606
XP_002794301 589 ------DYrHHIYVDDIPdikmP-NaKaaAHSKVGFDaEQ-G 622 Paracoccidioides lutzii Pb01
XP_002487142 552 ------DYhHHIYADDIPdvrvP-HaKysAHEKLGFDpEQ-G 585 Talaromyces stipitatus ATCC 10500
GAD91775     553 ------AYhHHIYADDLPdvrvP-QaKfaAHEKLGFDpTK-G 586 Byssochlamys spectabilis No. 5
Q4WZW6       552 ------DYhHHIYADDIPdvrvP-LaKfaAHEKLGFDpEK-G 585 Aspergillus fumigatus
CBF79728     556 ------DYrYHIYSDDIPdvrvP-NaTyaAHEKLGFDpEK-G 589 Aspergillus nidulans FGSC A4
EHA21143     555 ------DYhHHLYADNIPdvrvP-QaTyaAHEKLGFDvEK-G 588 Aspergillus niger ATCC 1015
EPS32694     551 ------DYhHHLYADDIPdirvP-QaKfaAHEKLGFDvEK-G 584 Penicillium oxalicum 114-2
XP_002844109 542 ------AYhHHVYIDDLIrqrsT-HaMgsVHRKLGFDtDK-P 575 Microsporum canis CBS 113480
EGE01310     542 ------AYnHNIYADDLVhkrdT-RpMgtVHRNLGFDtGR-P 575 Trichophyton equinum CBS 127.97
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