Conserved Protein Domain Family
Fungal_lectin

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pfam07938: Fungal_lectin 
Fungal fucose-specific lectin
Lectins are involved in many recognition events at the molecular or cellular level. These fungal lectins, such as Aleuria aurantia lectin (AAL), specifically recognize fucosylated glycans. AAL is a dimeric protein, with each monomer being organized into a six-bladed beta-propeller fold and a small antiparallel two-stranded beta-sheet. The beta-propeller fold is important in fucose recognition; five binding pockets are found between the propeller blades. The small beta-sheet, on the other hand, is involved in the dimerization process.
Statistics
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PSSM-Id: 369605
View PSSM: pfam07938
Aligned: 4 rows
Threshold Bit Score: 450.462
Threshold Setting Gi: 406861932
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EGE03468  35 TLPGTGIAAVNSVNL----LRIYSQDTSGGIREARFEG---YWSGGLAndTIAKARANSSIA-AASDDLELIRVYYLLPN 106 Trichophyton equinu...
EKD14984   9 IVNRTSIAAVGKTGKgagvMRVYTQDVYGGIREAGYNGsgsSWWGGDT--VIATGKISSPIAvAATPGLEHIRLYYITTD 86  Marssonina brunnea ...
CAP95833   9 IVFRTSIAACNASSH----LRVYMQDVMGKIRESRYED---KWSNGTEknAIASAKLYSPVA-CTSSDLENIRVYYLSTD 80  Penicillium rubens ...
EED49774   9 VLFRTGIAAVNSTNH----LRVYFQDSHGSIRESLYES---GWANGTAknVIAKAKLGTPLA-ATSKELKNIRVYSLTED 80  Aspergillus flavus ...
EGE03468 107 NTLGEAASDS---QSRWYTGSLNHYNFQVASHSRLAAVFVPSTQPPrLRIYAQLGDNTIQEFGYDVGrgWQHLANFGPAL 183 Trichophyton equinu...
EKD14984  87 FKLAELCYDEsdsGKGWFSGELSGKNYPIAPYSQIAATYLAVDDLK-IRVYVQAPDNSVQEYSNDGS--WYKDQHLGTAC 163 Marssonina brunnea ...
CAP95833  81 NTMKDMAYDK---SKGWYEGTLGKKRFMTAPYSKLAACQLKGPDMT-LRVYCQMADNTIQEYGVKDNgnWEKMSTLGSAM 156 Penicillium rubens ...
EED49774  81 NVLQEAAYDS---GSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALqLRIYAQKTDNTIQEYMWNGDg-WKEGTNLGVAL 156 Aspergillus flavus ...
EGE03468 184 PGTGIAALTYTt-GLRRSTTRVYFQTTDRHVVERVYD-NESWSDGGIV-VRTAKPHTPLAATSFLLTPGNpqSIRVYYGT 260 Trichophyton equinu...
EKD14984 164 PGSSIAVTAYK--GGPNASLRVYYQAPNLDLMEKAHDdGGHWETGKFS-VSSASPRAAISATSWTSSSGT--GIRVYYTG 238 Marssonina brunnea ...
CAP95833 157 PGTDIACTVFK---TSEPKIRVYYQHMEHGIIEKCYDsKRGWYDGAVK-FPKVQPRTSIACTSYMTSSEVv-GIRVFY-N 230 Penicillium rubens ...
EED49774 157 PGTGIGVTCWRytDYDGPSIRVWFQTDNLKLVQRAYDpHTGWYKELTTiFDKAPPRCAIAATNFNPGKSSi-YMRIYFVN 235 Aspergillus flavus ...
EGE03468 261 EDNRILEKGTEggTYWYDGAFEHSAIPGSQVAAVDW--GNGGVFNIRLYIQDGAFKNGISEWAWFRRs-WRRGILAIPPA 337 Trichophyton equinu...
EKD14984 239 PDDTILEKCND--GSWYDGAFNQESIPGSQVGCLSWyaASSKAPEIRVYFQNGIQVTAVSEWKWQDG--WNAGITALPPA 314 Marssonina brunnea ...
CAP95833 231 TSNMMREMVYDg-KSWTESQFHADCIPGTQIACVSW--MNGARPDVRVYFQAGHEISAITEYVWTQGr-WSSGKLALPPA 306 Penicillium rubens ...
EED49774 236 SDNTIWQVCWDhgQGYHDKRTITPVIQGSEIAIISW--EG---PELRLYFQNGTYVSAISEWTWGKAhgSQLGRRALPPA 310 Aspergillus flavus ...
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