2O3B


Conserved Protein Domain Family
NuiA

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pfam07924: NuiA 
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Nuclease A inhibitor-like protein
This family consists of protein sequences that are similar to the nuclease A inhibitor expressed by bacteria of the genus Anabaena ((NuiA). This sequence is organized to form an alpha-beta-alpha sandwich fold, which is similar to the PR-1-like fold. NuiA interacts with nuclease A by means of residues located at one end of the molecule, including residues making up the loop between helices III and IV and the loop between strands C and D. The mechanism of inhibition of nuclease A by NuiA is as yet incompletely understood.
Statistics
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PSSM-Id: 400328
View PSSM: pfam07924
Aligned: 28 rows
Threshold Bit Score: 115.423
Threshold Setting Gi: 504944592
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2O3B_B                   7 SEILEQLKQASDGL-LFMSESEYPFEVFLWEGSAP-PVTHEIVLQQTG------HGQDAPFKVVDIDSFFSRATTP-QDW 77  Nosto...
WP_012234558             4 EELLASLAEAAQGL-LFPSESDHELRPFRSRGD---ASSPAALLAAEG------LGAATPVEVTTAGDFFAPVIDV-PGD 72  Soran...
jgi:Cha6605_0717         4 AAIIDLLKQVTTDL-LWSSESDYPFEIVTWDRGV--AMTPTALFSKLA------NP-DAAIETISLTDLFAPVLTV-ENW 72  Chama...
WP_015151590             6 TPLTEQLAELTNRL-FWLSESEFPFQVIIWDTD---RVTIEQLLKLTY------HPPNTPVQTLTIHEFFAPALEGlGSF 75  Oscil...
jgi:Oscil6304_5860       3 QSITEELANLTQDL-LWMSEADYPWEVVSYDCS---NVTPENLLEQSN------LPSDTLIKTVTIERFFAPALRE-QSW 71  Oscil...
WP_015131694             6 ANLLAQLEELTPGIcLYYSDSDYTFKPIIWEVDTKgELTIENLLREVTppfdeyRPGGKIIKSANLDNYLQMIYQEaRKY 85  Calot...
PRJNA234054:Hsw_2589   170 DPALATLRDMTTGL-VYMSEGDAPLEPVSFAAPAG-SLTDATLAQLAG------LPADTKVEKQELTYFLRNHTAD-NGV 240 Hymen...
jgi:Cyan7425_4638       46 lriYRDLNTLTEGL-LYPSESDYALNLIRLPLNA--IPTNERLADLLG-------LGNKTVTSEQLDRFIRRRFTD-FAG 114 Cyano...
PRJNA61269:NIASO_17520   4 SNFLTQLQTQAQGV-LFMSESEYPFEPQNLGVLEA-AAIPAAVATHSG-------TANATVKTIAPEQFMAQLERS-ADP 73  Niabe...
jgi:Haur_4973           24 ETSVEKITAAANGL-LMMSETDAPFTPFAWDAAT--PFSPEALAN------------GQPIQTISLEQFLGNATTV-QEW 87  Herpe...
2O3B_B                  78 YEDEENAVVAKFQKLLEVIKSNL--KNPQV------------YRLGE-VELDVYVIGETPAGNLAGISTKVVET 136 Nostoc sp. ...
WP_012234558            73 AGDAALAEAGRYRRLVDLLERHL--TDVRV------------YRVGR-VAIDVYVVGRHPSGAWLGLVTKVVET 131 Sorangium c...
jgi:Cha6605_0717        73 YEDAELAQVKRFTDLLHAIESNL--ADVKV------------FRVGE-VEIAIYIVGKTPDGEPIGLKTHAVET 131 Chamaesipho...
WP_015151590            76 SYLLDQALIGRYRILYNYLTYYL--DNIKV------------YRVGT-HPIYIYIMGITRDENLAGIATQIIET 134 Oscillatori...
jgi:Oscil6304_5860      72 HNEEERATRNRFQQLFNFLNEQL--NDLIV------------YRFGE-VEIDVYVLGTVEDKT-VGLKTTLVET 129 Oscillatori...
WP_015131694            86 DPDIAVEIAQIYQTVIKLLQSSL--TFLEVaeirelndpnstFRI---------IFGSTKSGEWIGIapqleae 148 Calothrix s...
PRJNA234054:Hsw_2589   241 LGNPELA--NRFKALQMYLKQEL--SGTQV------------YRLGTgPQVPVLVLGEAEGGKLQGFKTVLTET 298 Hymenobacte...
jgi:Cyan7425_4638      115 IDPETRTTYRRFRELGAYFNRTFgaTNCHA------------YRIDT-IQVKVLFLGFKPGCGYIGIQTVAIET 175 Cyanothece ...
PRJNA61269:NIASO_17520  74 GDAPIVANLQKIKNLYAFLNSQL--SGLQV------------YRVEAgVQVPIYILGFLPDQTVAGVKTTSIEs 133 Niabella so...
jgi:Haur_4973           88 HGEAEKATVSQFQQLVEVLKAEL--TDIQV------------YRVGE-INIDAYIVGKDSAGNLVGLKTQLVET 146 Herpetosiph...
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