Conserved Protein Domain Family
EAR

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pfam07897: EAR (This model is not part of the current CDD release)
Ethylene-responsive binding factor-associated repression
The EAR motif is the ethylene-responsive element binding factor-associated amphiphilic repression motif. This motif binds to the Groucho/Tup1-type co-repressor TOPLESS (TPL) and TPL-related proteins. The motif is frequently to be find at the N-terminus of NINJA, or Novel INteractor of JAZ, proteins. The EAR motif, defined by the consensus sequence patterns of either LxLxL or DLN xxP, is the most predominant form of transcriptional repression motif so far identified in plants. It is highly conserved in transcriptional regulators that are known to function as negative regulators in a broad range of developmental and physiological processes across evolutionarily diverse plant species. This family is closely related to family AUX_IAA Pam:PF02309 which also has an LxLxL signature.
Statistics
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PSSM-Id: 517953
Aligned: 25 rows
Threshold Bit Score: 41.8137
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6AT41         2 DDENGLELSLGLSLGGTSGKSKARDAplepkaepqVEESSSKGV 45  Japanese rice
XP_020886913  58 EDEKDVELTLGLSLNGQFGTDPRSRKrkn----fdLGRSSSIPE 97 
EEF47754      44 NDKPDINLGLSLSLGGIYCENSNEKT---------LSRSSSSIG 78 
XP_002884637  15 DENVDVELELCLSLGGPFKKTEKSKP---------IGPSESVEC 49 
XP_003562743  28 EAEEAVELSLGLSLGGCFGASSGRDAkkp---rlqLARSSSIGS 68 
XP_002465644  29 EEMEAVELSLGLSLGGRFGLDRKGDK---------LPRSSSVAA 63 
XP_052147488  29 MEAEEVELNLGLSLGGRFGLDRRGEK---------LARSSSVAA 63 
XP_002438161  30 aMEEDVELSLELSLGGLFGPARKRDKd-------kLPRPSSAAA 66 
XP_002887227  41 EEDDEIELNLGLSLGGRFGVDKSNNNk--------LVRSSSVVV 76 
KAH0681637    46 DDINEDELNLGLSLGGRFGIDKSSSNl--------LVRSSSIAA 81 
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