Conserved Protein Domain Family
DUF1648

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pfam07853: DUF1648 
Domain of unknown function (DUF1648)
This domain is found in proteins expressed by bacterial or archaeal species. Some of these are annotated as being transmembrane proteins, and in fact many of these sequences contain a high proportion of hydrophobic residues. One protein containing this domain is immunity protein SdpI from Bacillus subtilis, which provides protection for the cell against the toxic effects of its own SdpC killing factor, and also functions as a receptor/signal transduction protein.
Statistics
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PSSM-Id: 489240
Aligned: 185 rows
Threshold Bit Score: 34.2637
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_011522205   13 WLGLVAMVYEIWsVYDRLPAVIASHFNAAGVPNGWAPKgQFFTVIVPIA 61  Candidatus Korobacter versatilis
WP_015623236   20 TVLVVTAAVGAW-RYPHLPPSTVLHFDTGGTPDWTVPT-SPAVAFLPVy 66  Actinoplanes sp. N902-109
Q8Y8J1        148 LIFIITLAITVV-FYSTAPVDFPIHFDMSGTVTDTVAKsPRVVLLLPMM 195 Listeria monocytogenes
13_pfamImport   1 -IMAITFAVGAV-GYVHMPDMIPMHMGFDGTVNDWAEK-TPLILWMPVL 46 
WP_015256119  147 LVAAATAWICIA-YYDDFSDRIVMQYGMDGTPTNVVDK-SPGIVLFPVW 193 Thermobacillus composti
WP_014096257  142 sVTAATFLMTWL-CYGRIPDRIAMHYDFNGTPTDWVEKsYRTVFELPTV 189 Heyndrickxia coagulans
7_pfamImport    1 FIVLIPIFIGLA-LWNQIPDQVPTHFDFSGNPDDYSSK-FQAVFFLPFF 47 
1_pfamImport    1 LIILFPLIIGLI-LWGELPEQIATHFGANNAPDGWSSK-AMTVLGLPFL 47 
WP_022239530   16 IMILLPMIIGVV-LWDKLPSEIATHFGTDNQANGWSSK-PMTVFGMPLL 62  Blautia hansenii
Q9HK69        142 ILIIAIFSVGIV-YYPHIPAMFATHYGISGAPNQYSAKsPFTVFLLPVL 189 Thermoplasma acidophilum
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