Conserved Protein Domain Family

pfam07835: COX4_pro_2 
Bacterial aa3 type cytochrome c oxidase subunit IV
Bacterial cytochrome c oxidase is found bound to the to the cell membrane, where it is involved in the generation of the transmembrane proton electrochemical gradient. It is composed of four subunits. Subunit IV consists of one transmembrane helix that does not interact directly with the other subunits, but maintains its position by indirect contacts via phospholipid molecules found in the structure. The function of subunit IV is as yet unknown.
PSSM-Id: 400267
View PSSM: pfam07835
Aligned: 38 rows
Threshold Bit Score: 38.502
Threshold Setting Gi: 123252671
Created: 11-May-2020
Updated: 7-Aug-2020
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
Format: Row Display: Color Bits: Type Selection:
Q0BXF1           8 RG-------EMDIHAQKATWDGFMAGSTWGSLIIIMTVGYATLAI 45  Hyphomonas neptunium ATCC 15444
jgi:Astex_1553  11 KG-------EMNIHEQSETYDLFMGLTKWGSLIIAVGILFFVLLF 48  Asticcacaulis excentricus CB 48
Q9A398           7 RG-------EMDIQEQAATYDAFGKMTKWGSLAISVLLLFFTLLF 44  Caulobacter vibrioides
WP_012284956     7 RG-------EMDIHEQAATFEGFGKMTKWGSLAIAVLLLTITLWF 44  Caulobacter sp. K31
zuci:PHZ_c3104  57 RG-------EMDIAEQRSTYHLVMLMTKWGSLYTAALILLLTMWF 94  Phenylobacterium zucineum HLK1
Q3IZW6          16 HPahgHVAGSMDITQQEKTFAGFVRMVTWAAVVIVAALIFLALAN 60  Rhodobacter sphaeroides 2.4.1
jgi:Pden_0432   28 HG-------EMDIRHQQATFAGFIKGATWVSILSIAVLVFLALAN 65  Paracoccus denitrificans PD1222
WP_020949009    12 HG-------EMDIRVHQKTFAGFIRLATWVCGISAAVLVFMALVN 49  Paracoccus aminophilus
Q163D7           6 HG-------EMDIEAQEKTFDGFMRWSMRTVIAIIVLIIWMAIFI 43  Roseobacter denitrificans OCh 114
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