Conserved Protein Domain Family
RED_C
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pfam07807: RED_C (This model is not part of the current CDD release)
RED-like protein C-terminal region
This family contains sequences that are similar to the C-terminal region of Red protein. This and related proteins are thought to be localised to the nucleus, and contain a RED repeat which consists of a number of RE and RD sequence elements. The region in question has several conserved NLS sequences. The function of Red protein is unknown, but efficient sequestration to nuclear bodies suggests that its expression may be tightly regulated or that the protein self-aggregates extremely efficiently.
Links
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Statistics
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PSSM-Id: 517901
Aligned: 11 rows
Threshold Bit Score: 149.138
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EFX85643     390 YAECYPGFEEMNDALE-DSDDE-ADYSKMDLGNK-KG-PVGRWDFDTAEEYGDYMNKKEALPKAAYQYGIKMAD-GRKTR 464
XP_009028213 399 YAECYPGMMESVDALG-DSDDE-ADYTKMDQGNK-KG-PVGRWDFETQEEYSTYMSAREAMPKAAFQYGVKMAD-GRKTR 473
3_pfamImport   1 YAECYPGAPENDDAIL-DSDDE-VDFSKMDVGSK-KS-TVGRWDFDTQEEYGEYMSKKEALPKAAFQYGVKMAD-GRKTR 75 
EDO37189     417 YAECYPGAMEVADTTY-DSDDD-ADYTKMDLGNK-KG-PIKRWDFEDEEQYNSYMETREALPKAAFQFGIKMSE-GRKTR 491
XP_002117518 433 YAECYPGAMEVDDAMA-DSDEE-ADYSKMDMGNK-KG-PVGRWDFENEEDYNKYMEKREALPKAAFQFGVKMAD-GRKTR 507
Q9N4U5       428 YDECYPGGLVEMGGAW-DSDEE-ADYSKMDAGPK-KNqAVNRWDFDTEEEYASYMEGREALPKAAYQYGVKNGEgGRKNK 504 Caenorhabditis ...
XP_002952015 546 YAECYPGMAGYVGALV-DSDDEgGDLNHMDSKQA-KG--KTRADFATDEEWQRYKESRETLPRAAFQYGVKRAD-GRKSH 620
EFH57059     450 YSECYPGYQEYNHEIV-GSDEE-ADLSKMDMGGKaKG-GLHRWDFETEEEWEKYNEQKEAMPKAAFQFGVKMQD-GRKTR 525
XP_001954757 433 YAECYPGLEEMNDAID-DSDDE-VDYTKMDLGNK-KG-PIGRWDFDTQEEYSDYMSTKEALPKAAFQYGVKMQD-GRKTR 507
NP_649865    434 YAECYPGLEEMNDAID-DSDDE-VDYTKMDLGNK-KG-PIGRWDFDTQEEYSDYMSTKEALPKAAFQYGVKMQD-GRKTR 508 fruit fly
XP_002129642 411 YAECYPSTQFNIAGLGeDSDDE-ADYSKMDNGHK-KG-PVGRWDFDTQEEYSSYMSKKEAMPKAAFQYGIKMSG-GRKTR 486 vase tunicate

EFX85643     465 NKTvv--ktD-KTEKAELDREWQKIQSILHKRKGGPSGEPQK 503
XP_009028213 474 RAG------P-RDDKKELDREWSKIQNIISKRKPGDDIALGN 508
3_pfamImport  76 RIPt-----K-KDEKAKIDRDLQKINAILSKRKPAESGEASS 111
EDO37189     492 RTG------P-KDEKTKLDRDWQRISRMLATKSKSEEDGERG 526
XP_002117518 508 RQG------V-KDDKSKLDREWQQISNIIKKRKEMGTGGPVS 542
Q9N4U5       505 KQS------A-VSDAKRLDRELNEINKIMDKRKAGGDGAGGG 539 Caenorhabditis elegans
XP_002952015 621 KELekgavvEqRQRDQKLDGQLRKIERLLQDKGHDHGQAFAR 662
EFH57059     526 KQN--------RDRDQKLNNELHQINKILTRKKMEKEGGDVA 559
XP_001954757 508 KNKt-----E-KNEKAELDREWQKIQTIIQKRKMPKDGGGGG 543
NP_649865    509 KNKt-----E-KNEKAELDREWQKIQTIIQKRKLPkdggggg 544 fruit fly
XP_002129642 487 RTR------E-QNEKQKLNRELQQIQQIITKRKGGPSSSGDY 521 vase tunicate
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