Conserved Protein Domain Family
GCK

?
pfam07802: GCK 
GCK domain
This domain is found in proteins carrying other domains known to be involved in intracellular signalling pathways (such as pfam00071) indicating that it might also be involved in these pathways. It has 4 highly conserved cysteine residues, suggesting that it can bind zinc ions. Moreover, it is found repeated in some members of this family; this may indicate that these domains are able to interact with one another, raising the possibility that this domain mediates heterodimerization.
Statistics
?
PSSM-Id: 400244
View PSSM: pfam07802
Aligned: 28 rows
Threshold Bit Score: 71.1983
Threshold Setting Gi: 297849644
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Q9LZL1        76 EDQKFVEFMKGGGCKESFTAWnDDCNfteEEAEK-NK---DLVTKCAGLFGTFSKCMDTHSDY--YHPILAVKKTTEEHL 149 thale cress
XP_009120280  53 EECSFCTYIKAGECKESWIEL-EKCL---DEAKKkDGe--SDVTKCKEARKMFKTCIYDNPVH--YEPVIAAETYMFAKM 124 field mustard
Q9FKK9        82 GECPLCQFIKGGECKEAFTEL-ENCC---DEAKK-NNe--DHVSKCKEARLIFKTCMYDNPVY--YEPLLAGEARAMAKM 152 thale cress
Q9FKL7        51 GECRLCRFIKGGECKESFIAL-EQCV---DEAEEsGEe--SDFTKCKEVRAKFKTCMYENPVY--YEPILAGEARAIAKM 122 thale cress
EFH69247      74 ieLRVSEFMIKGACKESFTAL-KDCV---DEAK-------SHPKKCDEFFPRLNKCMHAHSDY--YQPILALVKASEEMM 140 Arabidopsis lyr...
XP_002892703 104 kakqVSEFMRD-PCRESIRSF-RR-----RDAEYtRNnntLTFHRKLEAFDTVYKCMEAHSDYnqYQAFLASMKRRYEYY 176 Arabidopsis lyr...
XP_002890572 104 RDEMFTKFMIRGDCKEAFMAW-NDFC---KEAKKnNKs--CLHTPTMD---TLFKCMKAHSDY--YHPLLTVFKNAEEHF 172 Arabidopsis lyr...
EFH66834     102 rDELLGKFITRGGCKEAFMAW-RDSY---EEAKK-NKg--SLYTPALN---TLSKCMEAHSDY--YQPLLAVVKNYEEHY 169 Arabidopsis lyr...
XP_002889961 121 lEEKVLAFMKGGGCEEQCTAW-RDCF---EEAEK-NKe--DVDIKCAGVHAMWFNCMDAHSDY--FHPFLAPLKTAGEDF 191 Arabidopsis lyr...
XP_002892784 178 EEERLLAMLKGGGCKESFMAW-LDCS---EEAEK-NKq--DFITKCAGVSAKLDKCLDAHSEY--YQPYFAVVKTAEEHM 248 Arabidopsis lyr...
Q9LZL1       150 EKE 152 thale cress
XP_009120280 125 LSD 127 field mustard
Q9FKK9       153 LSE 155 thale cress
Q9FKL7       123 LNG 125 thale cress
EFH69247     141 KKE 143 Arabidopsis lyrata subsp. lyrata
XP_002892703 177 DKE 179 Arabidopsis lyrata subsp. lyrata
XP_002890572 173 KKE 175 Arabidopsis lyrata subsp. lyrata
EFH66834     170 SKE 172 Arabidopsis lyrata subsp. lyrata
XP_002889961 192 EKK 194 Arabidopsis lyrata subsp. lyrata
XP_002892784 249 ENE 251 Arabidopsis lyrata subsp. lyrata
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap