Conserved Protein Domain Family
DC_STAMP

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pfam07782: DC_STAMP 
DC-STAMP-like protein
This is a family of sequences which are similar to a region of the dendritic cell-specific transmembrane protein (DC-STAMP). This is thought to be a novel receptor protein that shares no identity with other multimembrane-spanning proteins. It is thought to have seven putative transmembrane regions, two of which are found in the region featured in this family. DC-STAMP is also described as having potential N-linked glycosylation sites and a potential phosphorylation site for PKC, but these are not conserved throughout the family.
Statistics
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PSSM-Id: 400231
View PSSM: pfam07782
Aligned: 115 rows
Threshold Bit Score: 79.192
Threshold Setting Gi: 532079323
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CUT99402      550 FDNGHITSQFVAQERRAlehgrpTALPLTHSERMNYVALTACKWSKAERNAAVGSLVFLFVGMITLVLIIFADYAMYQVV 629  Echinococcus ...
3_pfamImport    1 FDNLYITEKLEKLALEK------DGSHLLTASRVKLIRSTGLKLSRREIFHCIIRSLILVSFVMFTTVVIATDHITYQFA 74  
XP_015220051  262 FDNVYITRQLERLARR-------NGIEILPGDAKKLISSRGCRMSQQEFLRCVPYLLVITSYLILTLVVIAVDHMVFHFI 334  spotted gar
NP_001014362  252 FDNTYLTSGLRKKAVE-------KGLVVESKDVKNGVKSTSFRITKREFFRCLAPALVITLYLLMTVFLIVLDHFLYSLV 324  zebrafish
XP_005448520  260 FDNGYISKELLQ------------KMPINERPAKNKINLENCKVISQECSSCFLSLIVVTLYFIAITLIVVLDHVVYYIV 327  Nile tilapia
XP_011475821  260 FDNGYISKELLQNEPCE-----------TKRSIRDKTKLGSCLMTNQECTSSFLSLIVVTLYFTAIALIVVLDYVVYYIV 328  Japanese medaka
XP_005057217  266 FDNFYITKKLERLATDR------RAAHLLVGSSKKLIRPTGLRLSWEEVALCLVRAMLVTVALMLMLVLVAMDHFAFSVA 339  collared flyc...
XP_030144637  266 FDNFYITKKLERLAADK------RAAHLLVGSSKKLIRPTGLRLSREEVVLCLVQAMLVTVALMLMLVVVAMDHFAFSVA 339  zebra finch
XP_016848491  278 FDNIYITKKLEYLAQER------KTIHLLSCTSRKLIKPTGLKLTREELMTSLTHIFLLTLVLILTLVIIATDYIAFHLA 351  green anole
XP_005986829  207 YDNIYITKNLEDLAQKN------NTVDILSSCSRKIIKSMGLKMSHQEVLGCLFRMLLISIYLFLTLIIIATDHILFYVI 280  coelacanth
CUT99402      630 LTTSPAF---STGFGEVQQtleegisdqisdfgigaseqvVPEIqgnstmse-----igrsfmnL-ANPlkdiaf----- 695  Echinococcus ...
3_pfamImport   75 LTVGEWVvkvPSVPIVF-----------------------EIDYlitykklh-----lvllvkkTfFVEsnkpisksf-- 124 
XP_015220051  335 VAGGLWLsgdPYVTATI-----------------------DVKYtvrr--------------itpiCSLfhsscdeeilr 377  spotted gar
NP_001014362  325 KSGGPWIsnmPSTNVSV-----------------------NINLkvgtkvpilqltgtdgyn------------------ 363  zebrafish
XP_005448520  328 QMIAPWLldfPPTSAVI-----------------------SVNYkvqw-------------fppAfCIIpqscikrelvn 371  Nile tilapia
XP_011475821  329 QLVMPWVvdfPPTAASISL---------------------NYKVelfvpvlclipsscvtqtltN-FHRdyrwdf----- 381  Japanese medaka
XP_005057217  340 DTAVRKAaqfSAVPVTL-----------------------NIRYkveigpvpflfkifrrpsee---------------- 380  collared flyc...
XP_030144637  340 DTAVRKAaqfSAVPVTL-----------------------SIKYkaevgimpflfkifwrpsea---------------- 380  zebra finch
XP_016848491  352 QAAVSEAtqfPVVPISF-----------------------WIKYdvstkatspktnsllffqvkltfieffgkvfnnafs 408  green anole
XP_005986829  281 RTIADWVfdfPTVPMDV-----------------------TVNYnvkvvsfpiplkeav--------------------- 316  coelacanth
CUT99402      696 ----------------svdatICRPRP-SEPDHETTILIGLALVLTLLSIIVQVYVLRLRHLILAWYYPDGANRRAAWLR 758  Echinococcus ...
3_pfamImport  125 ------------hwdmtfvssQCRTQA-TPPDDSVAITVVIICGVIFAMILMEAYAQRLCRKISASFYKQREDQRVSYL- 190 
XP_015220051  378 hq-------kpyhwsfnlvpgRCVIEP-SKPDSGVVLQLGLLYLMAYILVVFEVYIRRVRRRVSASFFKRQEERRIVFLY 449  spotted gar
NP_001014362  364 ---elfnfnrtytalihsdpnICEAQS-SQLNPGVVTALVFLYLFSYTLLPLDVYARRLRRKVAASFFQQQEERRVEFLi 439  zebrafish
XP_005448520  372 fh-------rdykwnfspgpsLCDVTT-SAPNLGVTLLLGCLWLMSYFLVFLEVYARRLRRKISASFFRKQEEKRIAYLm 443  Nile tilapia
XP_011475821  382 ----------------npepsNCAVTT-SAPNGGVTFLLGCLWLMSYFMVFLEVYAKRLCRKICASFYREQEERRMTYLR 444  Japanese medaka
XP_005057217  381 --lllgdfnktyhhhlvfssaRCRTSApTAPNRSVLLAVGLLFLLLYSTVLLETLARRLCRQIAASFFPSREQRRVLHLY 458  collared flyc...
XP_030144637  381 --lllsdfnktyhhhlifssaRCRISPpTPPNPSVLLVVGLLFCILYGTVFLETYARRLCRSIAASFFQSWEEKRALHLY 458  zebra finch
XP_016848491  409 ieqskspfersyyqnltflsaNCSLRYpKPPNTAVTFAVGLLYCIIYAITFLETYSRRLCRKIAASFFKNQEDQRIQYLY 488  green anole
XP_005986829  317 -------sfqkdyhwnfpfftgCTMKA-SPPNNSVAFVIGLLYLIAYIMVFLEAYASRLRRKIAASFFEHQECQRVDYLY 388  coelacanth
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