Conserved Protein Domain Family
MFMR

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pfam07777: MFMR 
G-box binding protein MFMR
This region is found to the N-terminus of the pfam00170 transcription factor domain. It is between 150 and 200 amino acids in length. The N-terminal half is rather rich in proline residues and has been termed the PRD (proline rich domain), whereas the C-terminal half is more polar and has been called the MFMR (multifunctional mosaic region). It has been suggested that this family is composed of three sub-families called A, B and C, classified according to motif composition. It has been suggested that some of these motifs may be involved in mediating protein-protein interactions. The MFMR region contains a nuclear localization signal in bZIP opaque and GBF-2. The MFMR also contains a transregulatory activity in TAF-1. The MFMR in CPRF-2 contains cytoplasmic retention signals.
Statistics
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PSSM-Id: 400228
View PSSM: pfam07777
Aligned: 39 rows
Threshold Bit Score: 93.1928
Threshold Setting Gi: 695030726
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q84LG2         1 MGSSEMEKSGKEk-ePKTTPPSTsssapatvvsqepssAvSAGVAVTQDWSGFQAY-----SPMPPHGY----VaSSPQP 70  thale cress
P23922         1 MGSNDPSTPSKA---SKPPEQEQpp-----------atTsGTTAPVYPEWPGFQGY-----PAMPPHGFfpppVaAG-QA 60  bread wheat
Q6Z2L2         1 MGTNDPGTPSKA---TKASEPEQsp-----------atTsGTTAPVYPEWPGFQAY-----SAIPPHGFfpppVaASPQA 61  Japanese rice
XP_004960729   1 MGSSGADTPSKT---TKASAPQEqqp---------patSgAATPAVYPDWSSFQAY-----PPIPPHGFfpspVaSSPQG 63  foxtail millet
XP_009385711   1 MGSGEGEASAKS---PKPLAGQEqsp----------ttSsAAAVSVYPDWSNFQAC-----PPIPPHGLfpspVpSSPQA 62  wild Malaysian ...
ERN15534       1 MGNGEVDTSAK----PKTSAPQEqpp----------asTaT----VYPDWSAIQAFynpgtPPIPPPGFfhssVaSSPQA 62  Amborella trich...
XP_006599195   1 MGSSDMDKTPKEe--SK-TPPATsqe---------qssTtGMPTT-NPDWSNFQTY-----SPIPPHGF----LaSSPQA 58  soybean
XP_004244410   1 MGSSEMDKSSKEakeAKESKPPNsqe---------qtsTtTAGPV-NQDWSGFQAY-----SPMPPHGF----MaSSPQA 61  tomato
XP_009400763   2 GGS---ETDCKG---AKTSATQEqpp----------aaSsSPGAAVYPDWSGFQAY-----SPVLPHGFfhspVvSSPQS 60  wild Malaysian ...
XP_009395315   1 MGSSEADPSAKA---PKTSAAQEqtp----------atSsTPAVTVYPDWSSFQAY-----SPIPPHGFfhspVaSNPQP 62  wild Malaysian ...
Q84LG2        71 HPYMWGVQHMMPPYGTPPhPYVTMYPPGGMYAHPSL 106 thale cress
P23922        61 HPYMWGPQHMVPPYGTPPpPYM-MYPPGTVYAHPTA 95  bread wheat
Q6Z2L2        62 HPYMWGAQPMVPPYGT-PpPYM-MYPPGTVYAHPST 95  Japanese rice
XP_004960729  64 HPYMWGAQPMIPPYGTPPpPYV-MYPP-GVYAHPSM 97  foxtail millet
XP_009385711  63 YPYMWGAPHLMPPYGTPLpPYL-TYPPRGLYSHPSV 97  wild Malaysian banana
ERN15534      63 HPYMWGPQHIIPPYGTPPhPYVAMYPHGGLYAHPSM 98  Amborella trichopoda
XP_006599195  59 HPYMWGVQHIMPPYGTPPhPYVAMYPHGGIYAHPSI 94  soybean
XP_004244410  62 HPYMWGVQQFMPPYGTPPhPYVAMYPHGGIYAHPSI 97  tomato
XP_009400763  61 HPYMWGAQHLMPHYGTPPpPYV-MYPH-GIYAHPSM 94  wild Malaysian banana
XP_009395315  63 HPYMWGPQHLMPPYGTPPpPYV-MYPPGGLYSHPSM 97  wild Malaysian banana
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