Conserved Protein Domain Family
DUF1620

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pfam07774: DUF1620 
Protein of unknown function (DUF1620)
These sequences are mainly derived from predicted eukaryotic proteins. The region in question lies towards the C-terminus of these large proteins and is approximately 300 amino acid residues long.
Statistics
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PSSM-Id: 400226
View PSSM: pfam07774
Aligned: 154 rows
Threshold Bit Score: 104.925
Threshold Setting Gi: 74777681
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_014171554  791 FENTFMCTFFADyrvddsaniaaTIKGYHLTVSDLYESLEPNERGWGaaaaavrhssssnetaawfsSSLEPveaeegaa 870  Grosmannia cl...
Q5CTP8        734 FQNIILITSFHS-----------NYKVPVILILELFQFIKDETSTGInmldkfiflvssk----------------knvk 786  Cryptosporidi...
A0E6E8        116 DDHKVFVTYQNQ-----------AKMIFEIWTVEIYHMKRSVHLQKCqsiiislkiqqiniim--------------kqn 170  Paramecium te...
A0CJK9        666 DEHQVFVTYYNK-----------AQMMFEIWTVEIYHAKIEVSFIKMlenyyftktp---------------------ii 713  Paramecium te...
Q245W3        775 DENGVFVSYYNP-----------VYSIFQIWTVELFSKKMENNFVSMlqnyyfsesgak------------------yed 825  Tetrahymena t...
Q57ZY7        598 VEHAVLYHFMDV-----------EKMRHSLGVWEMFETEVG--------------------------------------- 627  Trypanosoma b...
CAM71841      594 VEHAIVYYYLDA-----------KKMRYCFGVWELFEDENS--------------------------------------- 623  Leishmania in...
EFC49614      698 DENTLVYQYTNA-----------KQMRHELTTVELFNNGTDFQKKGFgsilmeklfgsk------------------eag 748  Naegleria gru...
ESS33187     1076 YDNVVMAHYWNL-----------QQARYELHFVELQDAQKDEGP-----------------------LSIIFsaarhivp 1121 Toxoplasma go...
EED90102     1009 SENWVVYTYFNQ-----------RTRRTDVGVLTLHEGMIDKNGitafsap----------eqeltfSSLES-------- 1059 Thalassiosira...
XP_014171554  871 avattLEPAV--VSQTWVV--GARLRA---------------------------------LAVSQTRQGITVRQVLaYLP 913  Grosmannia cl...
Q5CTP8        787 eskiysekHVhvQETTFLYnyELPIDY---------------------------------SLLSKTSESLASKIIL-FGS 832  Cryptosporidi...
A0E6E8        171 tilfsnskyidfLQQVYGF--PLGIKY---------------------------------LGITRTRKSLTKKNLL-IIT 214  Paramecium te...
A0CJK9        714 tnyykadfEAffLQQVYGY--PLGIKY---------------------------------LGMSRTQKSLTKKNLL-IIT 757  Paramecium te...
Q245W3        826 fnylnenmDIiaLEQKYGY--SLGIKK---------------------------------MAVVTTKLSLTKRNLM-IIT 869  Tetrahymena t...
Q57ZY7        628 --------PVlfKDTGATP--PQVISSffsrhkrvfssratwppvvvgsvlgmhgggvakMSVTTSFGAIARKSLL-FVF 696  Trypanosoma b...
CAM71841      624 --------PVvfKTAGATI--PQIIASffvntkrefssratrppivvvstlgsfggpladMGVTTSYNAIARKSLV-LAY 692  Leishmania in...
EFC49614      749 vftsfgysKPtsRKNTYIL--PFGVRS---------------------------------IGVTKTTIGVTNKQFI-LSL 792  Naegleria gru...
ESS33187     1122 rltgfELPPPtgISQTYIL--PTGVRA---------------------------------FGVTATLQGITTRAILlATS 1166 Toxoplasma go...
EED90102     1060 -----AKPIV--LSKTYGL--AKPVTA---------------------------------LGVTTTKAGISSKQFM-FAT 1096 Thalassiosira...
XP_014171554  914 GTHGVLG-LPRvgAFLDARRPVg---------rDPTPAE------LE-EG---LTRYAPAFEVDPRLVVSHERDVVGIR- 972  Grosmannia cl...
Q5CTP8        833 EKSNVFEcIPE--RLFSTLRPN-----------------------KSkKK---NLIHNSNLPF-YQSILSE-----RIKf 878  Cryptosporidi...
A0E6E8        215 TFSQMYQ-LDR--NLVSARRREn----------SDLDHPf------------------vQLTYRLFNMNSLF-IF-KVC- 260  Paramecium te...
A0CJK9        758 TSGQLHS-LDR--NLVSTRRREk----------A--DQPile-ysLQsAE---LPPYQYQLPINFLNMLSYHQTF-DIE- 816  Paramecium te...
Q245W3        870 PNNQIHS-LDR--DILSTRRAVk----------LPKDNQlqnafsFEsTT---LPPYNYMVPIDRLSIISYHANLNDIK- 932  Tetrahymena t...
Q57ZY7        697 TSGRVAS-VGLnrLLAGGQVSL---------------GD------GAgQLthvIIP--------STAIVTHRYRAARPT- 745  Trypanosoma b...
CAM71841      693 ATGRVVV-VELrhLLAGNQMPL--------------PGA------KDrQMshlLLP--------SFLFASHKYRVAFPR- 742  Leishmania in...
EFC49614      793 TNDQIYL-VDK--KIIDARRPR-----------NPTAASde-----iaEG---LMPYNPYIPFVSLNVPTYNKPVSRVK- 849  Naegleria gru...
ESS33187     1167 SSHQIYT-MST--RLANARRPRlvderglplkeAGPAQQ------QQeEG---VLPYHPLLPLLPHDCISYYNQVFHVR- 1233 Toxoplasma go...
EED90102     1097 KNDQVVS-MDR--RMLDPRRPNg----------ELKESE------KM-EG---LMRYSPILPIIPLRTPSHVYEVSSVQ- 1152 Thalassiosira...
XP_014171554  973 -------AIVAAPT---------HVESTSVVLAF-GrVDVFGTR-VAPSLTFDLLDKSFGKASMLATVAALAVGVAVLRP 1034 Grosmannia cl...
Q5CTP8        879 stkfnskKIFSFPHe--------TYESKSKLLSV-G-FNSLEVFeIYPNTSFDLLPYDFNYYNIINTVFLILTITAISIY 948  Cryptosporidi...
A0E6E8        261 -------QLTIKHSiskgfqqnlQIQNPMPFLSF-----MVLTI-ITPYKSYDMVQKNFNYDAVILTTVLITLTIQVSQK 327  Paramecium te...
A0CJK9        817 -------KFSIEST---------NLESSALLLVY-G-SDIFFTR-IAPDKTYDMLLDNFNYNALIVTTVLIVVATKVLSK 877  Paramecium te...
Q245W3        933 -------EIYFSGS---------NLESTILFVAY-G-NDVFMSS-IAPDRTYDMINEDFNYILVTLSIIICFVGVFIAKK 993  Tetrahymena t...
Q57ZY7        746 -------LIATRPT---------NLESSCHVLVS-G-MDLFYVR-TSSGKEFDLLNSDFNKTLLIALTCSFGVLSLVARY 806  Trypanosoma b...
CAM71841      743 -------KITTEPT---------LLESSCHVVVS-G-LDLFYVR-SSSGKPFDLLNSDFNKPLLITLVCGFAALSVMARY 803  Leishmania in...
EFC49614      850 -------HIQTSPS---------ILESTTLMASS-G-LDVFFTR-LSPSKKFDILNEDFSYAMLIISTSALFISVFVAKY 910  Naegleria gru...
ESS33187     1234 -------GIAAHHT---------LRESTSSTFAF-G-LDLFFSP-VQPAKGYDVLSSQFNYGLLAAAMVTLLVLVVLTRW 1294 Toxoplasma go...
EED90102     1153 -------SIASTSA---------NVESQSLMLAYgG-PDVFFFR-LAPSKGFDLLPDDFNRGLLSVVLVGLLVLLISIQT 1214 Thalassiosira...
XP_014171554 1035 MVTKKQIDMRW 1045 Grosmannia clavigera kw1407
Q5CTP8        949 FSKRNQLK-KW 958  Cryptosporidium parvum
A0E6E8        328 LIKSSKQVKQF 338  Paramecium tetraurelia
A0CJK9        878 LVKSSKQVKQF 888  Paramecium tetraurelia
Q245W3        994 YASQSNLH-RL 1003 Tetrahymena thermophila SB210
Q57ZY7        807 FAMRKGVRQLW 817  Trypanosoma brucei
CAM71841      804 FVNRKALNSAW 814  Leishmania infantum JPCM5
EFC49614      911 LANKKEVQLKW 921  Naegleria gruberi
ESS33187     1295 RAKEADLAAKW 1305 Toxoplasma gondii VEG
EED90102     1215 MNKKKMATTVW 1225 Thalassiosira pseudonana CCMP1335
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