Conserved Protein Domain Family
DUF1619

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pfam07773: DUF1619 
Protein of unknown function (DUF1619)
This is a family of sequences derived from hypothetical eukaryotic proteins. The region in question is approximately 330 residues long and has a cysteine rich amino-terminus.
Statistics
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PSSM-Id: 400225
View PSSM: pfam07773
Aligned: 68 rows
Threshold Bit Score: 133.051
Threshold Setting Gi: 122100068
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002503963         75 CLCDLTEGTCDANCCCDPDCDSNEKAQFTECATCVYD-GAnaamngkvclpegrsppslEYCLPSSTVSRVNLlss---s 150 Micromon...
2_pfamImport          1 V------GECDINCCCDNDCSEDDKNVFTTCFPDSFHaHRt------------------GLCYSPKFLYKNNT------- 49 
OXU27470            281 CSCDLTTSVCDINCCCDLDCTEYHFKVFSHCIDREIDkEKd-----------------nWYCHEKPFFRHNDT------- 336 Trichoma...
EGI68878            212 CECDLIKSSCNINCCCDIDCNHSHLSAFSYCQNYHVElYDs------------------RYCYNRNFIQRNNT------- 266 Panamani...
WGS:AAQB:GK15385-PA 129 CSCDLREGICDLNCCCDRDCPSEILVVFN--------------------------------CLGLEAPAELQTrledfqy 176 Drosophi...
WGS:AAPU:GI17529-PA 149 CSCDLRQDLCEVNCCCDRDCSQESLQVFS--------------------------------CLPEQ---HTRLedfq--y 191 Drosophi...
XP_001988149        271 CACDLHSDVCELNCCCDRDCPPEALLVFS--------------------------------CAQPATEEQLRRrledfqy 318 Drosophi...
EDS36993              9 yyenrRINICDVNCCCDIDCSDQILRTFS--------------------------------CSEER------Ldvaeyhh 50  southern...
Q16V00              262 CKCDLKINICDVNCCCDIDCSESVLRTFA--------------------------------CDEEE------Ldieeyhh 303 yellow f...
EEC12108             74 CFCDLKRNSCDVECCCDSDCTEDDAKSFSFCVDRVPEaPDl------------------RYCTKRDAIFASRT------- 128 black-le...
XP_002503963        151 slGVVEQRKADMSFlsqqlCIKDD-NSASl-------gKYFLDP-GFATD-DILkSSVTLQS--ERFWNPVPAAASEt-- 216 Micromon...
2_pfamImport         50 --SYKVLKEDKGLL-----CIAQDnLPERlhyrnqkilSTFSAFnKIWKRrKHFlWTLLQSNemYIFRN----------- 111
OXU27470            337 --RFILEKIVDSLF-----CVASDnLPPV-----------YSATsHLQIEdEKSfKKVINNNkpSKFKWILEQKKLIvpe 398 Trichoma...
EGI68878            267 --PFIFEKLANNLF-----CILYDnLPSIy---------------STNNNlVLYeEELWKIIemNNYKWEIRHSKTLfky 324 Panamani...
WGS:AAQB:GK15385-PA 177 thGLPTCQLHDGWL-----CVFRSnTKPV----------------KMQPIfRDFdSSKYRKWpdLLEAYETDNVPST--- 232 Drosophi...
WGS:AAPU:GI17529-PA 192 nhGLPTCQISDGWL-----CVFRShTKPA----------------KKQTPsQIFdSKDYNRWpeQLDAFETALPAPPm-- 248 Drosophi...
XP_001988149        319 nhGLSTCQLNDGWL-----CVFRSnSKPP----------------KIKAQsNNFdAEQYKKWpeLLVAYESQLPLATq-- 375 Drosophi...
EDS36993             51 reGLQSCEVQGGLF-----CLVGEhRPPEeged--gggVFYDP--NLKESsSKY------KWseIFPVGDVPKRGP---- 111 southern...
Q16V00              304 qeGLQSCEVQGGLF-----CLVGErRDTTr-------gTVSKKFrNLNHAaSNYeIATKRKWidIFPVDTNSKDKI---- 367 yellow f...
EEC12108            129 ---LFEKRPVGDLL-----CVVVDnVRKK---------DVFGEPpSVSSP-ADV-HKLVEESrhGWMADGAEQTT----- 184 black-le...
XP_002503963        217 ---QPKYRHNDTIGVVKAASEpllpGNKFVLPGAtfSGVCGWTNVIGYnmplpasAASEDATCLVPIDDTlSKSCTTL-- 291 Micromon...
2_pfamImport        112 ---DHHYKFGVPIWRFNNPGS----LTTIAFPISiySRMCEDMRIIKY-------LENFESVCLVQSPAS-RKSCENNn- 175
OXU27470            399 fniSNSYRHGDILWKINKNS-----LQPLELPQTgfGKACDFKKTVKF-------LEDWKDSCH-------QNNLNNKnv 459 Trichoma...
EGI68878            325 -nlSKYYQHGDILWKLHDKS-----IEEIEFLQSgfTGICTFKKILRY-------LQNWKGACI-------QNKLTNInp 384 Panamani...
WGS:AAQB:GK15385-PA 233 ---QSHYKLGQALQLWHPESKe---SSVFMLPTSyeTAHCHIRQAIRH-------LQPTENNCL-------MNDINQLqe 292 Drosophi...
WGS:AAPU:GI17529-PA 249 ---TSHYKFGQALQLWQPESKs---LANWELPMAyeSASCQLKQTLLY-------LQPMESSCL-------LADATQLqm 308 Drosophi...
XP_001988149        376 --fTAHYKYGEALQLWQPDSKt---VSYFELPIGyeSASCQLKRTLLH-------LQPMHSSCL-------MSDASQLql 436 Drosophi...
EDS36993            112 ---VSTYRVNDRIKLYNETSEk---IETLTLPFSltNSECQLAQPVRY-------LRDQSTEC--------LRSLEDLel 170 southern...
Q16V00              368 ---ASSYRVNDIIKFYNETSEh---VEPFNLPRSltNSECQILQPIRF-------LQDQTTECL-------RTSLDELes 427 yellow f...
EEC12108            185 ---KVRFKAGDALLRLEDDGG----VGEWSECVGasFTACEATEAVTY-------LRDQVFECTRGVGVL-DNWCTSDp- 248 black-le...
XP_002503963        292 --L--NAKYLVNDLKLaktpgss-atpteaPTISSMKYRSRIGGKLTDLTGTVPaatftd---------gsggsgAAD-- 355 Micromon...
2_pfamImport        176 -aL--NAAKLINTTLIsn-----------pLLVNISNLEAISEEHLVTIQTILCvdgngc----------letkqIPEpi 231
OXU27470            460 flFptN----FSNFTI--------------VALPLKF------NSQFLLQNCPNsicrainvsycsdswtlckknITVqs 515 Trichoma...
EGI68878            385 ylFtvT----FSNFTV---------------------IKSLPSFNDTLTTNQMCqsniclpvrihyclksfsacnRTSis 439 Panamani...
WGS:AAQB:GK15385-PA 293 nlA--LILNITSNYQVlgkprdieetevegINMQ---------------------------------------------- 324 Drosophi...
WGS:AAPU:GI17529-PA 309 nlW--SLLNLTNSHQLlsrpre--leeqqvHGLNITICQQLLLQPKIQCLEhn--------------------------- 357 Drosophi...
XP_001988149        437 nlW--TLLNLTNSHQLlskprelddqdlqgINIQ---------------------------------------------- 468 Drosophi...
EDS36993            171 fnL--ALLEQQAFVRYlrspkaei-------------------------------------------------------m 193 southern...
Q16V00              428 ftT--TLMEQQSHLRYlrlpkaei-------------------------------------------------------m 450 yellow f...
EEC12108            249 -aL--SAQTYYRGFAI----------------------------------SSSAedrvqvlptlcsgdvcsdfppSAHva 291 black-le...
XP_002503963        356 ------TCNF------------------------------AVVEAHYVITHDGSGSISSFAVDLVFADVMTSTRwsavyn 399 Micromon...
2_pfamImport        232 ydhtsnLCRN------------------------------TIKSVQYVIRHNGTSGIKEAQCTITLHNIYLNV------- 274
OXU27470            516 ycteksVCYN------------------------------IVKKMRYMIYHNGSEGIQNIEVQIQLANISD--------- 556 Trichoma...
EGI68878            440 gfcmnsTCTN------------------------------IVKGLKYVIRHNGSAGINSIDAYFNIGNASH--------- 480 Panamani...
WGS:AAQB:GK15385-PA 325 ------ICQLwqsvnltrklac-------fdqandtqldmIVDKIELEFLHNYT-NILGVKLLLREAPTRQTESe----- 385 Drosophi...
WGS:AAPU:GI17529-PA 358 ----etQSEL------------------------------LVDRIELQLLHNYT-NILEAKLLLREASVEDDKT------ 396 Drosophi...
XP_001988149        469 ------VCQQlllkpkelcl-----------eanetevdiLVDSIELQLLHNYT-HILAAKLLLREANQQDENE------ 524 Drosophi...
EDS36993            194 ehcldeDCFNssvrfcdlsgqncqktnqssvndpegsyswYCPEVKIRFVHNYT-HLTAMETRLLCGSIDLEQD------ 266 southern...
Q16V00              451 ehcmdqDCFNssiqfcsfaglncrttnssesnddgsgepwYCPRINFEFQHNYT-HLEGLNIKLLCGRAELFDMkg---- 525 yellow f...
EEC12108            292 sytddgECRN------------------------------VVSQVTYRIVHNGVHGIINITARYETTTLQSGAT------ 335 black-le...
XP_002503963        400 angaladpgnpsSVRVKYTVSW--------KLSaetvvPRSGAPGYVVGAP 442 Micromonas commoda
2_pfamImport        275 ------------AFKQEYKVTFewaknesnIFE------RSGTPGYIDGKP 307
OXU27470            557 ------------SFKQEFEILHkwiglnqsLVF-----ERSGNPGYIAGKP 590 Trichomalopsis sarcophagae
EGI68878            481 ------------PFYQYFEVEYkwidsnntQIF-----IRSGNLGYEMGKP 514 Panamanian leafcutter ant
WGS:AAQB:GK15385-PA 386 ------------ELWLHYKVSFksvn-etaSKP------ISGPLGYLTGKP 417 Drosophila willistoni
WGS:AAPU:GI17529-PA 397 ------------MLWLTYALVYqsveelntKPS-------SGALGYELGAP 428 Drosophila mojavensis
XP_001988149        525 ------------EIWLTYQLSFesin-aikAKP------SSGPLGYVQGAP 556 Drosophila grimshawi
EDS36993            267 ------------TIWQRISVEFkrkdeekfSRK------VSGNLGYLVGKP 299 southern house mosquito
Q16V00              526 -----------dKIWTRLSVKFtrkneekfSRS------VSGNLGYLKGKP 559 yellow fever mosquito
EEC12108            336 ------------EFLQRFRTFYvwlsdgisPAA-----ERSGNPGYLPGLP 369 black-legged tick
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