4UNM,4UNM,4UNM


Conserved Protein Domain Family
Kelch_2
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pfam07646: Kelch_2 (This model is not part of the current CDD release)
Kelch motif
The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Drosophila melanogaster Kel is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.
Links
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Statistics
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PSSM-Id: 517800
Aligned: 44 rows
Threshold Bit Score: 28.4625
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4UNM_A  257 RWYPTLTT-LG-------DGKILSVSGLddig------qlvPGKNEVYDPKTKAWTYTDKV 303  Streptomyces lividans
Q9CAE9  166 GLMTNVSK-VI-------DEKIYIVGRVw-----------aSATIVEFDLRTEKWADGTKP 207  thale cress
Q9SZZ9  179 ELFRVSVS-VL-------DQKIYVAGLHqedg-----sdslKNSVTVLDTETQVSDRVAIP 226  thale cress
Q9FFV5   80 KLMSCTAC-VL-------DEKIYVSGRCkd---------gdSMTFQVFDTNTQTWDPLSVP 123  thale cress
Q7Z6M1   30 ARVGHSCS-YLppvgnakRGKVFIVGGAnpn--------rsFSDVHTMDLGKHQWDLDTCK 81   human
Q39610  241 NVCDGIES-VP-------YHKVFSFGGRkgm-------mqyLNTVEVMDCGTQMWSTPPVD 286  Chlamydomonas reinhardtii
Q9UF94  114 PRSGFSVAmAP-------NHQTLFFGGVcdeeeeeslsgefFNDLYFYDATRNRWFEGQLK 167  human
Q9SJM2  264 PRAYHTMT-CI-------GARHLLIGGFdgk--------ltFGDLWWLVPEDDPIAKRSSV 308  thale cress
P87061  187 GRYGHTIS-CL-------GSKICLFGGRlldyy---fndlvCFDLNNLNTSDSRWELASVV 236  Schizosaccharomyces pombe 972h-
Q9P3K9  565 TRMCHSLT-DF-------GTAQLLVGGRaspstp--lkdcwLLEKTNGSESEWAWKRTNDL 615  Neurospora crassa OR74A
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