5DIY


Conserved Protein Domain Family
NAGidase

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pfam07555: NAGidase 
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beta-N-acetylglucosaminidase
This family has previously been described as a hyaluronidase. However, more recently it has been shown that this family has beta-N-acetylglucosaminidase activity.
Statistics
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PSSM-Id: 429533
Aligned: 76 rows
Threshold Bit Score: 314.894
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5DIY_B            7 RGIIEGFYGKPWEHQERLDMFEFMQANNLNAYIYAPKQDLYHRELWREPYKEEQL-QLFKELIEKAGSCGINFTFAISP- 84   Thermobacul...
P26831          187 RGFIEGYYGNPWSNEDRAELMKFGGDYKLNQYVFAPKDDPYHNSKWRDLYPEEKL-SEIKKLAQVGNETKNRYVYALHPf 265  Clostridium...
CDA64348        181 RGFIEGYYGNPWSLEDRIDLMKFGGEIKMNQYVFAPKDDPYHNSQWRELYPTENL-ENIKKLAQAGNENKCFFVYALHPf 259 
EDK24328        191 RGFIEGYYGNPWSTEDRVNLMKWGGYYKLNAYFYAPKDDPKHRTQWDQLYTEEELaNKIRPLAEAGNESKCRFVYALHPf 270 
WP_118516294    182 RGFIEGYYGNPWSTEDRKKLMEWGGYYKLNSYFYAPKDDPKHNSKWRELYTDEEIeTKIKPLAEAGNKSKCRFVFALHPy 261  Coprobacill...
WP_015287569    189 RGAIEGYYGNPWSLQDRINYMRWGSYYKLNGYFYAPKDDPKHSHKWRELYTESEIeNLIKPLAREGNRTKVRYIYTLHPf 268  Mycoplasmop...
kribb:BBB_1496  106 RGFIEGYYGNPWSTQDRINLMKWGGYYKLNSYFYAPKDDPKHNSQWRTLYTQDELdTKIKPLADAGNASKTRFVFALHPf 185 
Q8XKW3          192 RGFIEGYYGIPWSNENRKDLMKFGGDFKMNSYIFAPKDDQYHSLKWREPYPAEKL-AEIKEMVDVGIATKNKFIWTIHPf 270  Clostridium...
WP_004613466    185 RGFIEGYYGIPWSNEDRMSLMRFGGDFKMTSYIFAPKDDPYHSAKWREPYPADKL-EEIKEMTEVGNASKCRFVWTIHPf 263  Coprococcus...
WP_009242515    197 RGFIEGYYGLPWSNEDRMSLMRFGGDYKMTSYIFAPKDDEYHKGKWRDLYPEEEL-AKIKEMVKVGNDSKCRFVWTAHPf 275  Lachnospira...
5DIY_B           85 ------GLslvyS---SEEELETLIRKITPFLEMGVHSIGIFFDNVPFDliheedrnsySNLAEAQADFLTRVLQRLEST 155  Thermobacul...
P26831          266 mnnp----vrfdTeenYQNDLGVIKAKFTQLLENDVRQFAILADDASAP----------AQGASMYVKLLTDLTRWLEEQ 331  Clostridium...
CDA64348        260 mn-------spfNfnnYNADLATVKAKYLQVIESGVRQIALLEDDAT------------GSSAANLSRLLNDLTNWLTEL 320 
EDK24328        271 pqgn---hlrfdDn--YEADLAKLQAKFKQVIDQGVRQIAILADDFW------------NPGGPNGVRLLNDMTAWLEEV 333 
WP_118516294    262 myna----irynSeenYQADLKVLQAKFEQVIKAGVRQIAILADDAG------------NVGGANYTKTLTDMTAWLKEM 325  Coprobacill...
WP_015287569    269 fgtrldND--------YDQGVKDLKNKFLQVIQAGVRQIGILADDVA------------RADIGTQVRLLIDMVTWLKEL 328  Mycoplasmop...
kribb:BBB_1496  186 mnna----irfnSeanYQADLKVLQDKFAQTIGVGVRQIAILADDAA------------NVGGNNYTKLLTDMVAWLKEM 249 
Q8XKW3          271 l---kdGMnf-gSeesYKADLEKIIAKFEQLYSVGVRQFGVLADDA-------------EGEANNQVKLMEDLEKWRLQK 333  Clostridium...
WP_004613466    264 m---ngGI----TeatYDADIQKIKDKFNQLYNVGVRQFGVLGDDAG------------NLPRKVVIRVMNDLQKWADEK 324  Coprococcus...
WP_009242515    276 m----gGF----NqaqADQEIQALLRKFDQLYDAGVRQFGVLGDDVG------------SLPRTIVINMMTKVSEWAKKK 335  Lachnospira...
5DIY_B          156 IST------PQIIMCPTFYCNDP-------NLEYLRILGQRLPKNIDVFWTGPNVCsHEITTSHMQEVQK------SL-Q 215  Thermobacul...
P26831          332 QSTypd-lkTDLMFCPSDYYGNG-------SSAQLKELN-KAEDNVSIVMTGGRIW-GEVDENFANNFMNnistegHP-G 400  Clostridium...
CDA64348        321 KNSkypdlkTDILYCPTDYMGNG-------SSAKLKGINASANRQVHMLMTGNAVW-GQVSANFADNFYNnvasngVA-G 391 
EDK24328        334 KKQypd-mkMTIPYVPYDYMGNG-------SSAELQELK-KAPANVQIVMTGGRVW-GEVTNNFTSTFTN------NV-G 396 
WP_118516294    326 QKTypd-lkLTLPFCTQEYMSNG------------QSYYRNFPANIQIVMTGGRVW-GEVTNNFTTTFTN------NA-G 384  Coprobacill...
WP_015287569    329 KQTkyhdlkVVLPFVVNEYAGYG------------QSYFKRFPNEVQIVMTGGKTW-GEVSPEFTNKFYS------NT-N 388  Mycoplasmop...
kribb:BBB_1496  250 KKTypd-lkTTLPFVTQEYMGNG------------MSYFANFPKEVQIVMTGGRVW-GEVSQNFTDTFTS------NV-G 308 
Q8XKW3          334 GDV------YEFIFVPKVYTKESagg--dvNNEYLKTIG-TMPETIDIMWTGDVIL-GYVTQETFEFFEE------AV-G 396  Clostridium...
WP_004613466    325 GDV------YDLVFCPQGYNHSWq-----gNYSELNELDEGFPEDVRIFWTGEAVC-QPIEQKTLDHFRRhnlpegKTeR 392  Coprococcus...
WP_009242515    336 GDV------YDTVFCPAGYNHSWqsggtggNYAELNEYDKGFPEDIKIFWTGEAVC-KPIEQVTLDHFRThrttdgQK-R 407  Lachnospira...
5DIY_B          216 RPATLWDNYPVNDGgmMPE-LHIGPYD-HRDPELHTh-VVGIYANPMALPEASKLPLYTFAQYLNSP--SQYNPQDSWRQ 290  Thermobacul...
P26831          401 RAPFFWINWPCSDN--SKQhLIMGGNDtFLHPGVDPskIDGIVLNPMQQAEANKSALFAIADYAWNIwdNKEEADENWND 478  Clostridium...
CDA64348        392 RYPYMWVNWPCNDN--YKTgLIMGGHNtILHTGIDGhkYEGIILNPMQHSEPSKVAIFTAADYCWKPwdAKEEGDQAWED 469 
EDK24328        397 RGPFMWINWPCTDN--SKKhLIMGGYDtFLHPGVEPskIQGIMLNPMQQSEPSKVAIFGNADYAWNIweTKEEADKSWND 474 
WP_118516294    385 RGPYMWINWPCTDN--SKKhLIMGGYTtFLHPGVDPnkIQGIVLNPMQQSEPSKVAIFGNACYSWNIwqSEEEAQKCWTA 462  Coprobacill...
WP_015287569    389 RGPLLWINWPCSDN--SKNhLILGGYReFLHKNVDPkkVQGIVLNPVQQSEPSKVALFGAADYTWNIwkDDAHIDQTYSD 466  Mycoplasmop...
kribb:BBB_1496  309 RGPYMWINWPCSDN--SKShLIMGGYDtFLHPGVDPskIQGIVLNPMQQSEPSKVGIFGNATYSWNIwrSKSEADQAWQD 386 
Q8XKW3          397 RQAFMWLNWPVNDI--NNKrLLMGKGE-MLDPTVTN--FKGIVTNPMQEAQASKVALFAIADYGWNR--ADFDMDKSWKD 469  Clostridium...
WP_004613466    393 RAPLFWLNWPVNDI--NHGrMLMGKGV-QLHTDINVndIYGAVTNPMQESEASKVAIFAVADYAWNV--KGFEVDKSWED 467  Coprococcus...
WP_009242515    408 RAPLFWLNWPVNDI--NHGrLMMGKGV-QLKPDVNPedLAGAVTNPMQESEVSKPAIFAVADYSWNI--AGFNMDKSWAD 482  Lachnospira...
5DIY_B          291 AVSTLl-----gEDNLSAMEKF 307  Thermobaculum terrenum
P26831          479 SFKYMdhgtaeeTNSSLALREI 500  Clostridium perfringens str. 13
CDA64348        470 SFKYIdhvtaleSDSSKALREV 491 
EDK24328        475 AFSFVdhnsaimNDASDALREL 496 
WP_118516294    463 SFKYVdhnsaieTQASAALREL 484  Coprobacillus sp. AF29-3BH
WP_015287569    467 AFNYVtnnsyqeTAESKAFRNL 488  Mycoplasmopsis cynos
kribb:BBB_1496  387 SFSFVdhnsavpTAASNALREL 408 
Q8XKW3          470 SFKYIe------PDASEELYTF 485  Clostridium perfringens
WP_004613466    468 SFKYIe------ADATEELHTL 483  Coprococcus phoceensis
WP_009242515    483 SFAYId------ENASEELHTL 498  Lachnospiraceae bacterium 1_1_57FAA
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