4KJM,2JNK


Conserved Protein Domain Family
FIVAR

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pfam07554: FIVAR 
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FIVAR domain
This domain is found in a wide variety of contexts, but mostly occurring in cell wall associated proteins. A lack of conserved catalytic residues suggests that it is a binding domain. From context, possible substrates are hyaluronate or fibronectin (personal obs: C Yeats). This is further evidenced by. Possibly the exact substrate is N-acetyl glucosamine. Finding it in the same protein as pfam05089 further supports this proposal. It is found in the C-terminal part of Bacillus sp. Gellan lyase, which is removed during maturation. Some of the proteins it is found in are involved in methicillin resistance. The name FIVAR derives from Found In Various Architectures.
Statistics
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PSSM-Id: 400096
View PSSM: pfam07554
Aligned: 204 rows
Threshold Bit Score: 29.5947
Threshold Setting Gi: 81420795
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4KJM_A    5 GNLQTAINDKSGTL--AsQNFLDADEQKRNAYNQAVSAA-------ETILNKQTGPNTAKTAVEQALNNVNNAKHALN 73   Staphylococcus aureus...
Q8NWQ6 2782 TKLDEEINKSVTTDgmTqSSIQAYENAK-RAGQTESTNA-------QNVI---NNGDATDQQIAEEKTKVEEKYNSLK 2848 Staphylococcus aureus...
Q8CP76 2583 NRLESKINETVQTDgmTqQSVENYKQAK-IKAQNESSIA-------QTLI---NNGDASDQEVSTEIEKLNQKLSELT 2649 Staphylococcus epider...
Q8CP76 3430 LNLENKINQTVQTDgmTqQSIEAYQNAK-RVAQNESNTA-------LALI---NNGDADEQQITTETDRVNQQTTNLT 3496 Staphylococcus epider...
Q8CP76 3597 RQLQDEIDQGTNTDg--------mTQDSVDNYNDSLSAAiiekgkvNKLLKRN----PTVEQVKESVANAQQVIQDLQ 3662 Staphylococcus epider...
Q8CP76 3680 NRLENSINQQTDTDgmTqDSLNNYNDKL-AKARQNLEKI-------SKVL----GGQPTVAEIRQNTDEANAHKQALD 3745 Staphylococcus epider...
Q8NWQ6 2866 TQLQNDIDQPTSTTgmT-STSIAAFNEKLSAARTKIQEI-------DRVLASH----PDVATIRQNVTAANAAKTALD 2931 Staphylococcus aureus...
Q8CP76 2667 NQLQANIDQKPSTDgmT-QQSVQSYERKLQEAKDKINSI-------NNVLANN----PDVNAIRTNKVETEQINNELT 2732 Staphylococcus epider...
Q8NWQ6 2949 NQLQHSIDTQTSTTgmT-QDSINAYNAKLTAARNKIQQI-------NQVLAGS----PTVEQINTNTSAANQAKSDLD 3014 Staphylococcus aureus...
Q8NWQ6 3032 TQLEQSINQPTDTTgmT-TASLNAYNQKLQAARQKLTEI-------NQVLNGN----PTVQNINDKVTEANQAKDQLN 3097 Staphylococcus aureus...
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