Conserved Protein Domain Family
RSD-2

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pfam07547: RSD-2 
RSD-2 N-terminal domain
This domain is found in three copies in the N-terminus of the C. elegans RSD-2 protein. RSD-2 (RNAi spreading defective) is involved in systemic RNAi. Mutations in the rsd-2 gene do not effect somatic genes but only germline expressed genes.
Statistics
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PSSM-Id: 400093
View PSSM: pfam07547
Aligned: 17 rows
Threshold Bit Score: 90.442
Threshold Setting Gi: 0
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EGT57735       91 FSDNPKHLTYKRKIGFTDWYGLVDCSQF-------QIQSGGVFTADIEINDF-KLDGHANCLFK-VSRQPFPRIRDDN-- 159  Caenorhabditi...
2_pfamImport    1 FSDDPAHKTFDLNLAFADWYGSVDSSAFkdqillySSGKKRVFNSLIIVNDL-KYKENGTQLFK-VHELGFPIVGKDAev 78  
O62256         96 FSSDPSHLTYDRNIGYADWYGPVNCSQFk-----aKNTKVAFFKYLIAVNDL-DYKNTGECLMK-AVQLVGVIDNRDA-- 166  Caenorhabditi...
Q9XUE3        227 CSSIETHITYPQSVAFADTFGKVNVAAE-------SMERGVTYRVELAINII-DSEANNVPLFK-ISDIGEKLTGEEN-- 295  Caenorhabditi...
XP_002634186  127 FSVESNHPTYSKKKAYAGVFGHVEVDENva----lRMERNQVYKAELTFNNStELSQKSTYGFK-VWSICGDASPEES-- 199  Caenorhabditi...
EFO92846       92 FSFLDTHPTYSKKKVYAGGFGHVEIEDHls----eKMDRGIVYKVELSLNVL-EIKDNQKPVFK-VTKVYELLESEDG-- 163  Caenorhabditi...
Q9XUE3        499 FSSNPKHKSYNKEVGVSDRYGFVEIPRIt-----gDFEFGTVYSTQITMV---QYGDPLKACFKaVAPLKRQFIDDLD-- 568  Caenorhabditi...
1_pfamImport    1 FSSDRDHLSHNKSVAVSDQYGYIQLPPDcdk-drqYWEEQTIYKVEIVIS---QFTDPVQPIFKvVSPLVTKFQRTQAad 76  
Q9XUE3         44 FGDNPNYLTYNRDLGYADWYGIVDCSDS-------PPTGPGVYKAFIYVNDL-NYQESGNPLFKvTGRLKFLANKDTS-- 113  Caenorhabditi...
XP_002634186  404 FSNNNGYKTYNRSCGFSNRFGLVEIADPa-----dGLLGNTVYSTNIEIK---QWLDPLEPVFRsVSKLK---EEDVEfs 472  Caenorhabditi...
EGT57735      160 VEFLEKMNSYED 171  Caenorhabditis brenneri
2_pfamImport   79 DEFLQNMNSHEK 90  
O62256        167 AEVRLKMMEFER 178  Caenorhabditis elegans
Q9XUE3        296 EAFLRKLNDFEE 307  Caenorhabditis elegans
XP_002634186  200 EAFMTSLYLYED 211  Caenorhabditis briggsae
EFO92846      164 EAFLNELYEFDE 175  Caenorhabditis remanei
Q9XUE3        569 -HYLQVMGKYED 579  Caenorhabditis elegans
1_pfamImport   77 EMFFSTIRKFEN 88  
Q9XUE3        114 -DTMMKLEIFEQ 124  Caenorhabditis elegans
XP_002634186  473 DDFANSMVQFEE 484  Caenorhabditis briggsae
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