8Y1U,2IZV,8OKX


Conserved Protein Domain Family
SOCS_box

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pfam07525: SOCS_box (This model is not part of the current CDD release)
SOCS box
The SOCS box acts as a bridge between specific substrate- binding domains and more generic proteins that comprise a large family of E3 ubiquitin protein ligases.
Statistics
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PSSM-Id: 517750
Aligned: 305 rows
Threshold Bit Score: 25.8924
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
8Y1U_A       265 QPRNLQDLCRIKIRQCI--GlqnLKLLDELPIAKVMKDYLK 303 human
NP_001107273 444 QPFSLQRICRAVISSRSsyD----G-IGTLPLPAALKEHLK 479
XP_007231032 475 FPFGLQSLARATICRGTt-Y---DG-IAALPLPQALQDYLR 510
XP_007255839 503 FPFSLQHLARAAICSQTt-Y---DG-IGALPLPPAMQDFLK 538
Q08D28       377 FPFTLQHICRAAICTSTnyD----G-IDALPVPSSMKLYLK 412 tropical clawed frog
XP_006160630 385 FPFSLQHICRTVICNCTtyD----G-IDALPIPPSMKLYLK 420
XP_009008733 165 KPFSLQFICRAIVCSRVkyD----G-VNLLPIPKCLMEYLQ 200
EEC06157     168 FAFSLQHLARAAICARIayD----G-ASRLPLPRSLRAYLR 203
2IZV_A       135 FPFSLQHICRTVICNCT--T---YDGIDALPIPSSMKLYLK 170 human
XP_014348742 382 VPFRLQHLCRSVISSCTtyD----G-IDVLPIPNSLKEYLK 417 coelacanth
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