Conserved Protein Domain Family
Hc1

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pfam07432: Hc1 
Histone H1-like protein Hc1
This family consists of several bacterial histone H1-like Hc1 proteins. In Chlamydia, Hc1 is expressed in the late stages of the life cycle, concomitant with the reorganisation of chlamydial reticulate bodies into elementary bodies. This suggests that Hc1 protein plays a role in the condensation of chromatin during intracellular differentiation.
Statistics
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PSSM-Id: 488957
Aligned: 41 rows
Threshold Bit Score: 33.3493
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_009035683   1 MSRFEEVVAQVSALEADFKKFYEQGNKAAGTRVRNGMNNLKKMAQDIRKEVTEIKNS 57  Indibacter alkaliphilus
BAG83893      16 ENLLVTIQENFTSFKKDATAQIEKGNKAAGTRARKISLTIEKALKEFRKKSIKASNE 72 
ROT18048       2 KELIEQISALGDTFIRNAETQLDKGNKAAGLRARRASLELEPMLKRFRKLSLEAVFG 58 
4_pfamImport   1 NELLEQLQMKMEAFQKNAALQADKGNKAADQRARCVSLEMEPLLKQFRKLSLAASKR 57 
WP_138106779   4 KETIQRLLHQIADIRHDLEKA-MEGNKAAAQRARTNTIRFSKTSKVFRKESVAAARS 59  Candidatus Rhabdochlamydia sp. T3358
WP_013942729   4 KDTVKKMHTMLEEMVGDLKKA-ERGIKAASQRVRTGTIKFAKLAKLYRKESMIAERG 59  Simkania negevensis
3_pfamImport   1 KDTVKNLRDLLQNITNDLEKA-EKGNKAASQRVRTGTVKLEKVSKLYRKESIKSEKT 56 
1_pfamImport   1 KDTIKSMKDLLEQISADLPKA-ENGNKAASQRVRTGTVKLEKTAKKYRKESISSEKG 56 
WP_041016416   4 KDTIKSLRGLLDQITADLPKA-ENGNKAASQRVRTGTVRLEKVAKLYRKESIKNEKG 59  Criblamydia sequanensis
P0CE15         4 KDTAKKMTDLLESIQQNLLKA-EKGNKAAAQRVRTESIKLEKIAKVYRKESIKAEKM 59  Chlamydia trachomatis D/UW-3/CX
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