Conserved Protein Domain Family
Herpes_UL37_2
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pfam07413: Herpes_UL37_2 
Betaherpesvirus immediate-early glycoprotein UL37
This family consists of several Betaherpesvirus immediate-early glycoprotein UL37 sequences. The human cytomegalovirus (HCMV) UL37 immediate-early regulatory protein is a type I integral membrane N-glycoprotein which traffics through the ER and the Golgi network.
Links
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Statistics
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PSSM-Id: 284761
Aligned: 2 rows
Threshold Bit Score: 419.014
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q6SW94 191 GYgvsvrctyhgtdinvTSNATsmnC----------RLNCTCNHTQIYNGPCAGAESKLPLNVTFRQSRrqwhsVMLTFG 260 Human herpesvirus 5 s...
Q69553  19 CF---------------TSNFT---CeqkivliqehKLRSICISTCYVNGVLAGNSSCVSVKTSYLINL-----AMLTNG 75  Human herpesvirus 6 (...

Q6SW94 261 FQ----------------------YHLEGWFpLRILNESRDINVTEVYGEVACFTNDTNiTMGQLTLNLTGRSYVLRAla 318 Human herpesvirus 5 s...
Q69553  76 FKamrvgnitsisektaflrviinYYFRGVM-LRALIAQRLPNAANLSSTVNCWLDDHS-AGGVMTLFYGTERIVLNS-- 151 Human herpesvirus 6 (...

Q6SW94 319 rtspfESSVN---WEETNVTDNATssenntvtvMSVLTVYAESDYIFLQDMCPRF----LKRSV------KLAKNNRRNT 385 Human herpesvirus 5 s...
Q69553 152 -----STEINasrWISDGQDANGT---------LNILNERVSLDIYFLSKICPQLsseiYKKKVahpkyfSLIKNDTKPK 217 Human herpesvirus 6 (...

Q6SW94 386 TFTGTNVTSlpewtlqqcqGWKYWTTlsimWKNRRSAL-----------LRAKSRALGHWALlsictvAAGSIALLSLFC 454 Human herpesvirus 5 s...
Q69553 218 KFLRNTWRS----------AWSNWYK----YKEIKEFLdfssdyenfseITYSMSAAGLFFL------AGGAFTMLLLLC 277 Human herpesvirus 6 (...

Q6SW94 455 ILLIGLRRDLLEDF 468 Human herpesvirus 5 strain Merlin
Q69553 278 CLSMITRKHIVKDL 291 Human herpesvirus 6 (strain Uganda-1102)
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