2I0Q


Conserved Protein Domain Family
TEBP_beta
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pfam07404: TEBP_beta (This model is not part of the current CDD release)
Telomere-binding protein beta subunit (TEBP beta)
This domain represents the OB fold from several telomere-binding protein beta subunits which appear to be specific to the family Oxytrichidae. Telomeres are specialised protein-DNA complexes that compose the ends of eukaryotic chromosomes. Telomeres protect chromosome termini from degradation and recombination and act together with telomerase to ensure complete genome replication. TEBP beta forms a complex with TEBP alpha and this complex is able to recognise and bind ssDNA to form a sequence-specific, telomeric nucleoprotein complex that caps the very 3' ends of chromosomes.
Links
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Statistics
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PSSM-Id: 517691
Aligned: 4 rows
Threshold Bit Score: 218.566
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2I0Q_B     23 NNEGDFSKVSSNLKKPLKCYVKESYPHFLVTDGYFFVAPYFTKEAVNEFHAKFPNVNIVDLTDKVIVINNWSLELRRVNS 102  Sterkiella nova
CDW85312   21 NLGGDFSKVSKDLKKPLKTYVKESYPHFLVTDGYFFVQPHFTKEAVAEFHQKFPNVNIVDLHDKVIVINTWSLELRRVNS 100 
CDW74302    3 SKNGEFSKIGDFKKAKIRCYVKETYPKFLISDGSYFISGYFTKDWLKNSE--KNKIRITDLNEGLILINKWSIELAKVNS 80  
CDW80594   21 NANFDFEAIPLQLKKSMRVGVQEHIAFFWVNDGYHFLEAVFTKEAVNEFRKNWPHLKFIGLKEKILLITKWSLRIREADS 100 

2I0Q_B    103 AEVFTSYANLEARLIVHSFKPNLQERLNPTRY--PVNLFRDDEFKTTIQHFRHTALQAAINK 162  Sterkiella nova
CDW85312  101 AEVFTSYANLEARLVVHSFKPNLQERLNPTRY--PVNLFRDDEFKTIIQHFRHQALQQSIAK 160 
CDW74302   81 AEDFTSYSGIEMRLIIHDFKVNKDEDLKMSKF--PTNLYRDDEVKSRVLEFIADQRSEKLAE 140 
CDW80594  101 RKLFTSYQNLQIQIVIEGFKPILHEKPNPKQHfqATNIYHDEEIQTYLRHKRHEMIRGFLSN 162
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