Conserved Protein Domain Family
A-2_8-polyST

?
pfam07388: A-2_8-polyST (488934 is an unknown moldel)
Alpha-2,8-polysialyltransferase (POLYST)
This family contains the bacterial enzyme alpha-2,8-polysialyltransferase (EC:2.4.99.-) (approximately 500 residues long). This catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid (PSA).
Statistics
?
PSSM-Id: 488934
Aligned: 19 rows
Threshold Bit Score: 136.904
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
WP_034632117   2 NLFIVSNLGQLIQAQNVIKQNDlidnvlv------vlwtkrnTVVRDNI---------INNVDN-------Q------FF 53   Halalkalibacte...
WP_079569926   3 TLHLVTGLYSA--VNSFASRYVgpeddhhvv------------------------vlfsdpadEpvlteriR------RL 50   Krasilnikoviel...
WP_103942705   3 QIFVSSRLFGAMSLAAAVDAGLfgppgrrri-----llvshdaeIPELT---------PPPNERpgyrpllS------RF 62   Thermomonospor...
WP_116023844   3 QIFVSSRLFGAMSLAAAIDAGHfgpsgrrri-----llishdaqIPELT---------PPPNERpgyapllS------RF 62   Thermomonospor...
WP_072402447   3 DLVAINGPWQVVTFLNFYMTEYgekspppctv-ifyeindelKRVCQLI---------LSSYDYvdqiydaK------DL 66   Flaviramulus b...
WP_015138221   4 RFAFVNGIWQLCMVVAAFEQER--------------------LHHPHTIykdylvvysLASANTelmdfveKnsykfwNW 63   Nostoc sp. PCC...
PSB20038       4 RLVFVNGIWQLCMVAAAFLQER--------------------AKHPEVKyqdylvlysRKTANTklvefvkTicdafwNW 63  
WP_046522834   3 ILYLCFTPYHI-KVSNYLSKTEyksdenhmil-------------------------------------sscsginenTL 44   Mesobacillus c...
WP_044664276  26 FIASSTSHWHALGIDAEINSNEelkqsggiifisphpkdgflIDSNDFI---------CSRSPK---------------- 80   Syntrophacetic...
CDC04958      24 VVAFCITPWHSVGIEVALEKLNslekqlnghlfickhpktglALSPTSVnlssygnfkTEIYNIpaasplkK------LF 97  
WP_034632117  54 SNVDTL-QLPNFPNKF-------HVNN------LMKIRKDYNHLIENY---PFTDVFVCN---YNSHYNFLYDIAKAKNI 113  Halalkalibacte...
WP_079569926  51 RGVKSVsFLADPPEYL-------------------EILADPERMTRLCagrAPDQLRMFL---SHSHWLLDALAGAFPDA 108  Krasilnikoviel...
WP_103942705  63 DEVISLnEVIAPQHPLswnprpeDLPM-------------LERLLRQVwglGADPVELAVe--AIQSSPAKTLAAIFHEA 127  Thermomonospor...
WP_116023844  63 DEVISLnELIDPLHPLawspaavDQPM-------------IERLLRRVwnlGDEPIELAVe--AIQSNPARSLASIFHDA 127  Thermomonospor...
WP_072402447  67 NNIIE--------------------------------RSFNNIWICKL-----------------FSFESKKLVDSFPLL 97   Flaviramulus b...
WP_015138221  64 QGVIQVkWVTSEWDRNlnkeqnsAVQEivkhfdLDSPDAVEEIWLCKI-----------------QFRDERFFADIFSQA 126  Nostoc sp. PCC...
PSB20038      64 DGVIQVdWTTADWNPQqnkadhlPVQQilqsfhLNSPATVDEVWLCKI-----------------QFRDERLCADIFSKA 126 
WP_046522834  45 KKFVKItQYKTLNYTDielslreGVKLga--syFKKYKSSIEHFIKTIkeqEYDKIVYFSdnpIAYQLLFNDIKQNSVNT 122  Mesobacillus c...
WP_044664276  81 IKIAMVnPIQTRPHELirltiklIINKiknktnTFYLLSPMTPKLLSL------------------RLFTETFLVNSCQL 142  Syntrophacetic...
CDC04958      98 DHIYHFfHIIKSPNFSadkpscyVISP---------LNPDYKTISDAM------------------------KLRPDENI 144 
WP_034632117 114 NINIFEEGL-GTYkfkvvldkmqennkikfierftiaqnfaikdfkqaikqtdlfkwlvflllfiknnlfnplfillkgm 192  Halalkalibacte...
WP_079569926 109 GVSLFEEGMaGLY------------------------------------------------------------------- 121  Krasilnikoviel...
WP_103942705 128 TVTVYSDGL-ATY------------------------------------------------------------------- 139  Thermomonospor...
WP_116023844 128 TVTVYSDGL-ATY------------------------------------------------------------------- 139  Thermomonospor...
WP_072402447  98 PIILFEEGM-HSYvhkqyftlmnv---------------------------------------------------irstd 125  Flaviramulus b...
WP_015138221 127 KIVMYEDGL-HTYla----------------------------------------------------------------- 140  Nostoc sp. PCC...
PSB20038     127 AIVIYEDGL-HTYap----------------------------------------------------------------- 140 
WP_046522834 123 KLMFVEEGT-GIYlknyrypfr---------------------------------------------------ykilifl 150  Mesobacillus c...
WP_044664276 143 NYILIDEGI-GTYlsssiwkrvqkddksnydifgniiiqlkngifrvfnsfiiy-------------------------- 195  Syntrophacetic...
CDC04958     145 IAVVVDEGLggrs------------------------------------------------------------------- 157 
WP_034632117 193 arICLSFFPIefvnkikkiktPKEL-------R-------------SFDGTIPMFDKAYFTFP--------DQGSELfka 244  Halalkalibacte...
WP_079569926 122 -----------------------PDnllplqfL-------------DRVVRVEYHHYLGAFAPlsal-drpELFEEIdat 164  Krasilnikoviel...
WP_103942705 140 ---------------------GATRatpprgvG-------------SRLSRLVHLDLVPGLTP--------HLLSEYgap 177  Thermomonospor...
WP_116023844 140 ---------------------GATRatpptgvG-------------SRLSRLLYLDLMPGLVP--------HLLAEYdap 177  Thermomonospor...
WP_072402447 126 tinkklKVSLkyffkkedlirFFPElilpthqK-------------KCIRNYYLFSLLASGNPk------nKISSQYvf- 185  Flaviramulus b...
WP_015138221 141 nnYLISLPQVnwihprealarYKKFvrevishEvdwyhkgikrshlRRIVKFYSVLGTQIPIPavfrnirvEYVNKNilq 220  Nostoc sp. PCC...
PSB20038     141 tsYLIHSPPIdwsnlrktlsgYKHLfgevishRidwqhegvkrshlRRIKKVYSVLGTQIPIPstlqkvpiEFVEPDllr 220 
WP_046522834 151 akILFNNNNIrvfmhgkggfeDEVLlr------------------------------------------epELIESKgkk 188  Mesobacillus c...
WP_044664276     --------------------------------------------------------------------------------      Syntrophacetic...
CDC04958     158 -------------------------------------------rfsWFISRIHDGINPLKSFItflqeitlDKISYSqlv 194 
WP_034632117 245 kq------ynelKLDYQLKKEVEyylkns-----------qtlslLDRKSVIFLDQVYn-----VPPEKHTEIIMKylne 302  Halalkalibacte...
WP_079569926 165 aftgale-----------------------------racgrhdagLTPDTVVLVEQYFdrkgdaVSTAELVDVYRQaa-h 214  Krasilnikoviel...
WP_103942705 178 g--------qelPGEAFLKVLDEvcaeidpl------isrygtlgEHDNAALIVGQYFsel-giLEPDEEDQMHLEmlqg 242  Thermomonospor...
WP_116023844 178 a--------eelSGEAFLKVIEEvtaevepi--------laghgefgDNVALIVGQYFsel-eiLTDEEENRLHLEmlqg 240  Thermomonospor...
WP_072402447 186 ----------nvLEQANRVLEPEsils------------------sgrpCVLVVGQYFsnl-dlLTFEYELNVYFRil-n 235  Flaviramulus b...
WP_015138221 221 ----------klFAELNHRFDCQlype---------------vthhHTKTALLIGSNFchl-dyFPRESEVAVFAHvi-q 273  Nostoc sp. PCC...
PSB20038     221 ----------sfFVDLNHRLQCEsrla---------------dtpsNSKTALLLGSNLshl-qsFPREREVEVFADti-r 273 
WP_046522834 189 iklskde-----------------------------freilinndCTENFVLEKGSLFcpsfiiNDPKVRNKAFNEif-l 238  Mesobacillus c...
WP_044664276 196 -----kcisvenrflfnnvknnlrvnatvrdnynklllananqypLQGPVALFVTNPYsey-nyVDVIDEYNNIVKkivq 269  Syntrophacetic...
CDC04958     195 kkgclidqtlfvKKHGNFFVQNKlaekyrsiletrnladdkqnfsIYENAIIINTQPFeet-gqLQNNADIYSLKKii-q 272 
WP_034632117 303 FYPQR--NIFIKMHPRSKTevrks-fedkiKK-----YNNIRLIe-lDVEMPFEAILVE--KKPKTIVSLTSTSLVYGPK 371  Halalkalibacte...
WP_079569926 215 DLLAKgyRVAYKPHPRHASevfea-vaadlPAelaggLSRMT-----DRDLPLEVLIAT--SRPAAVVAVNSTLLLTAPH 286  Krasilnikoviel...
WP_103942705 243 VVARGhsTVLFKPHPHSPPrlfel-ltdeaKRl----GARLVII---DDPVPAEAWFAR--ARPALVVGICSTAMMTARC 312  Thermomonospor...
WP_116023844 241 VVARGhdTVLFKPHPHSPPrlfel-lvdeaKRl----DARLVVI---DDPVPAETWCAR--VRPALIVGICSTAMMTAYR 310  Thermomonospor...
WP_072402447 236 YYIDKgfDVYWKGHPRNkmfd------qkiKEs---fGDNVKILk--NNSIPLEIFLIS--NPDIEVCGLSSSVLLYKAL 302  Flaviramulus b...
WP_015138221 274 KLTAQgyKIFWKEHPRNQIplfee-fkqiiTL------DNFVYLe-gEQKIPIEVIVSQ--NKIDLCVSTVSSSLFYLNY 343  Nostoc sp. PCC...
PSB20038     274 RLNEQgyTILWKEHPRNQKplfed-iqeivEL------DNFVYLs-nEQKLPIEVIVAE--SNIDLCGSTLSSSLFYMKQ 343 
WP_046522834 239 CYYQKreFLYVKLHPSEREvdslqklvesyDG---------YIIilnRDDLTSEDIIVN--PNIKEVISDVSSSLINAYY 307  Mesobacillus c...
WP_044664276 270 LLIKNgfKVIIKPHPREDPnkyqk-linknNN------GNIKIL---NKNKPIEKEIVL--IKPSVIVGFMSTALLTAKV 337  Syntrophacetic...
CDC04958     273 SLQNCgeKVIIKPHPREKNldrykdlgctiEK---------------RKGIAQEEILSTlkTKPKAVIGFCSTTLVTAKI 337 
WP_034632117 372 LISGTEVVSCA 382  Halalkalibacter okhensis
WP_079569926 287 LLGVPSFLLDV 297  Krasilnikoviella flava
WP_103942705 313 YFGIPTVTLGV 323  Thermomonospora echinospora
WP_116023844 311 YYGVPAATVGT 321  Thermomonospora umbrina
WP_072402447 303 LFNDKTKQCLY 313  Flaviramulus basaltis
WP_015138221 344 IYGIKTLTCAR 354  Nostoc sp. PCC 7524
PSB20038     344 IFGIKTVTCVR 354 
WP_046522834 308 LRDDIKIISYQ 318  Mesobacillus campisalis
WP_044664276 338 IFNIPAFTAVK 348  Syntrophaceticus schinkii
CDC04958     338 FWDIPTYSCIH 348 
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap