Conserved Protein Domain Family
HC2

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pfam07382: HC2 
Histone H1-like nucleoprotein HC2
This family contains the bacterial histone H1-like nucleoprotein HC2 (approximately 200 residues long), which seems to be found mostly in Chlamydia. HC2 functions in DNA condensation, although it has been suggested that it also has other roles.
Statistics
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PSSM-Id: 369339
View PSSM: pfam07382
Aligned: 8 rows
Threshold Bit Score: 90.9934
Threshold Setting Gi: 81312805
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AAA23130                  1 MLGVQK--KRSTRKTAARktVVRKPa------AKKTAAKKAP----VRKVAAKKTVARKTVAKKTVAARKPVAkkatakk 68  Chla...
CRI53323                  1 MIGAQK--KQSGKKTASR--AVRKP-------AKKVAAKRTVkkatVRKTAVKKPAVRKTAAKKTVAKKTTAK------- 62  Chla...
M.massiliensis:mma_2977   1 MATAAK--KPAAKKPAAKkaAAKKPaaakkpvAKKAAAKKPV----AKKAAAKKPVAKKAVAKKVVAKKKPVAkkaaakk 74  Jant...
Q7VUT9                    1 MATAKKaaKKAVKKPAAKkaAAKKAt-----pAKKAAVKKVA----VKKVAAKKPAVKK------VAAKKPAAkkvakka 65  Bord...
WP_004536238              1 MALAKK--KPAAKKAAAKkvVAKKAa-----pAKKAAVKKVA----AKKVAVKKVAAKKAAPAKKVAAKKVAAkkaaakk 69  Burk...
Q5L680                    1 MLGVQK--KRSSKKTATK--AVRKP-------ARKATAKKTA----TRKPAVKK-AVRKTAAKKATVRKTVSK------- 57  Chla...
Q254C1                    1 MLGVQK--KRSSKKTATK--AVRKP-------ARKAAAGKTV-----RKTVAKKTTARKTVRKTTTARKTVAKkaattrk 64  Chla...
Q823J8                    1 MLRVQK--KRSSKKTATK--AVRKP-------AKKAATRKPV----ARKTVAKKTTARKTVRKATTA------------- 52  Chla...
AAA23130                 69 apvrkavakk---------tvarktvakktvaarkPVAKKATAKKAPVRKVAAKKTVaRKTVAKKtvAARKPVAKKAT-A 138 Chla...
CRI53323                 63 -----------------------------------RTVRKTVAKKPAVKKVAAKRVV-KKTVAKK--TTAKRAVRKTV-A 103 Chla...
M.massiliensis:mma_2977  75 pvvkk-------------------avakkvvakkkPVAKKAAAKKPVAKKAVAKKVVaKKKPAAKkaAAKKPAAKKAV-A 134 Jant...
Q7VUT9                   66 v--------------------------akkavakkAVAKKAVAKKAVAKKAVAKKAVaKKAPAKKa-VAKKAVAKKAV-A 117 Bord...
WP_004536238             70 vavk--------------------kvaakkvaakkAPAKKAAAKKVAVKKVAAKKVAaKKVAAKKaaPAKKAAAKKAApA 129 Burk...
Q5L680                   58 -----------------------------------MTVRKTVAKKATAKKTATRKPAaRKTV-------RKTAAKTA--- 92  Chla...
Q254C1                   65 pavkkaaasrkpaakkattrkpvakkvatrkpavrKTVRKTVAKKTTARKTVRKTTTaRKTVAKKaaTTRKPAVKKA--- 141 Chla...
Q823J8                   53 --------------------------------------RKTVAKKTTARKTVRKATTaRKTVAKKt-VAKKPAVRKT--- 90  Chla...
AAA23130                139 KKAPVRKAV-AKKTVAKRVASTkkssva-vkagvCMKKHKHTAACGRVAASGVKVcASAAKRKMNPnrsrtAHSWRQQLM 216 Chla...
CRI53323                104 KKPVARKTT-VAKGSPKKAAACal---------aCHKNHKHTSSCKRVCSSTATR-KHGSKSRVRT-----AHGWRHQLI 167 Chla...
M.massiliensis:mma_2977 135 KKAVAKKPA-AKKAAAKKPAAKpaakkaaakkpvAKKPAAKKAAPKKPAAKPAAVaAPAVKTVLNP-----AAAWP---F 205 Jant...
Q7VUT9                  118 KKAVAKKAV-AKKAVAKKAP-------------------AKKAAPKKPATPPSTAaAPGAKTALNP-----AASWP---F 169 Bord...
WP_004536238            130 KKAAAKKAApAKKAAAKKAA--------------PKKAVVKKAAPATTASTASVApASGVKTALNP-----AAAWP---F 187 Burk...
Q5L680                   93 ---ATRKPA-ARKAVAKPAMS-------------CHKHHKHTASCQRVCASSAKR-RCGSKSRVRT-----AHGWRQQLM 149 Chla...
Q254C1                  142 --AASRKPA-ARKAVAKPALST------------CHKHHKHTAACKRVCSSSATR-RCGSKSRVRT-----AHGWRQQLM 200 Chla...
Q823J8                   91 ---TARKPA-ARKAIAKPAIS-------------CHKNHRHSAACKRVCSSSAKR-RCGSKSRVRT-----AHGWRQQLM 147 Chla...
AAA23130                217 KLVAR 221 Chlamydia trachomatis
CRI53323                168 KMMSR 172 Chlamydia pneumoniae
M.massiliensis:mma_2977 206 PTGTR 210 Janthinobacterium sp. Marseille
Q7VUT9                  170 PTGGR 174 Bordetella pertussis
WP_004536238            188 PTGSR 192 Burkholderia pseudomallei
Q5L680                  150 KLVSR 154 Chlamydia abortus
Q254C1                  201 KLVAR 205 Chlamydia felis Fe/C-56
Q823J8                  148 KLVSR 152 Chlamydia caviae
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